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Delayed-type hypersensitivity skin testing. A review.

Data up to Jan 2025

Published1983
Citations56
References200

Total Citations Per Year

Abstract

References (200)

Impaired immunologic reactivity and recurrence following cancer surgery

1970 • 668 citations

“Lymphokines”: Non-Antibody Mediators of Cellular Immunity generated by Lymphocyte Activation

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Thymus-Derived Rosette-Forming Cells in Various Human Disease States: Cancer, Lymphoma, Bacterial and Viral Infections, and Other Diseases

1973 • 561 citations

THYMOLYMPHATIC DEFICIENCY AND DEPRESSION OF CELL-MEDIATED IMMUNITY IN PROTEIN-CALORIE MALNUTRITION

1971 • 533 citations

Measurement of Delayed Skin-Test Responses

1975 • 516 citations

Delayed Hypersensitivity

1977 • 485 citations

An atlas of sensitivity to tuberculin, PPD-B, and histoplasmin in the United States.

1969 • 412 citations

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IMMUNOSUPPRESSIVE EFFECT OF SURGERY

1971 • 314 citations

STUDIES ON DELAYED HYPERSENSITIVITY IN HODGKIN'S DISEASE*

1962 • 285 citations

Thymosin Activity in Patients with Cellular Immunodeficiency

1975 • 283 citations

In Vitro Approaches to the Mechanism of Cell-Mediated Immune Reactions

1971 • 258 citations

Chemotherapy, Immunocompetence, Immunosuppression and Prognosis in Acute Leukemia

1971 • 248 citations

Suppression of Immunologic Responsiveness in Uremia

1965 • 248 citations

Delayed hypersensitivity in Hodgkin's disease

1972 • 244 citations

Morphology of delayed type hypersensitivity reactions in man. I. Quantitative description of the inflammatory response.

1974 • 241 citations

Hodgkin's Disease

1967 • 240 citations

Induction of a Fibrin-Gel Investment: An Early Event in Line 10 Hepatocarcinoma Growth Mediated by Tumor-Secreted Products

1979 • 230 citations

Salt Extraction of Soluble HL-A Antigens

1971 • 227 citations

Reactions in vivo and in vitro produced by a soluble substance associated with delayed-type hypersensitivity.

1968 • 225 citations

The booster phenomenon in serial tuberculin testing.

1979 • 217 citations

A Method for Dinitrochlorobenzene Contact Sensitization

1972 • 215 citations

The use of coccidioidin.

1948 • 202 citations

Frequency of Negative Intermediate-Strength Tuberculin Sensitivity in Patients with Active Tuberculosis

1971 • 196 citations

Immunologic alterations in bronchogenic cancer.Sequential Study

1968 • 190 citations

A Comparative Study of the Incidence of Anergy in Patients with Carcinoma, Leukemia, Hodgkin's Disease and Other Lymphomas

1962 • 189 citations

ELICITATION OF DELAYED ALLERGIC SKIN REACTIONS WITH HAPTENS: THE DEPENDENCE OF ELICITATION ON HAPTEN COMBINATION WITH PROTEIN

1952 • 188 citations

The delayed hypersensitivity response: application in clinical surgery.

1977 • 187 citations

Impaired Delayed Hypersensitivity in an Aging Population

1968 • 183 citations

Hodgkin's disease and immunity

1956 • 182 citations

Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells.

1976 • 177 citations

Effect of Intravenous Hyperalimentation on Established Delayed Hypersensitivity in the Cancer Patient

1976 • 163 citations

Morphology Of Delayed-Type Hypersensitivity Reactions In Man

1976 • 161 citations

MECHANISMS OF DEFECTIVE DELAYED CUTANEOUS HYPERSENSITIVITY IN CHILDREN WITH PROTEIN-CALORIE MALNUTRITION

1973 • 152 citations

Basic and Clinical Immunology

1977 • 152 citations

Effect of transfer factor on lymphocyte function in anergic patients

1972 • 149 citations

Role of the clotting system in cell-mediated hypersensitivity. II. Kinetics of fibrinogen/fibrin accumulation and vascular permeability changes in tuberculin and cutaneous basophil hypersensitivity reactions.

1975 • 147 citations

Immunological defect in aged population and its relationship to cancer

1965 • 145 citations

Impaired delayed hypersensitivity in systemic lupus erythematosus

1972 • 140 citations

IMPAIRED DELAYED HYPERSENSITIVITY IN PATIENTS WITH LEPROMATOUS LEPROSY

1966 • 138 citations

STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS

1969 • 138 citations

Delayed-type hypersensitivity and the immunology of Hodgkin's disease, with a parallel examination of sarcoidosis.

1966 • 127 citations

The delayed skin test response in Hodgkin's disease and lymphosarcoma.Effect of disease activity

1961 • 126 citations

Impaired Lymphocyte Transformation and Delayed Hypersensitivity in Sjögren's Syndrome*

1967 • 117 citations

Coccidioidomycosis and its treatment with amphotericin B

1958 • 114 citations

Interaction between 'sensitized lymphocytes' and antigen in vitro. I. The release of a skin reactive factor.

1969 • 114 citations

Inhibition of Leukocyte Migration: An Evaluation of this in Vitro Assay of Delayed Hypersensitivity in Man to a Soluble Antigen

1970 • 113 citations

TUBERCULIN REACTIONS IN MALNOURISHED CHILDREN

1965 • 113 citations

An Evaluation of Transfer Factor as Immunotherapy for Patients with Lepromatous Leprosy

1972 • 112 citations

The role of adrenocortical steroids in infection, immunity and hypersensitivity.

1956 • 112 citations

Development of delayed hypersensitivity to dinitrochlorobenzene in patients with Crohn's disease.

1969 • 111 citations

The multi-test system: a standardized approach to evaluation of delayed hypersensitivity and cell-mediated immunity.

1979 • 110 citations

Role of delayed hypersensitivity in predicting postoperative morbidity and mortality

1979 • 109 citations

Prevalence of Sensitivity to Coccidioidin, With Special Reference to Specific and Nonspecific Reactions to Coccidioidin and to Histoplasmin

1957 • 109 citations

Immunologic status of Hodgkin's disease

1966 • 108 citations

Story of the tuberculin test from an epidemiologic viewpoint.

1960 • 108 citations

Relationship of Pyridoxine to Immunological Phenomena

1964 • 104 citations

CUTANEOUS HYPERSENSITIVITY REACTIONS TO AUTOLOGOUS EXTRACTS OF MALIGNANT MELANOMA CELLS

1970 • 102 citations

Manifestations of immunologic unresponsiveness in Hodgkin's disease.

1966 • 101 citations

Delayed Cutaneous Hypersensitivity Reactions to Autologous Extracts of Burkitt-Lymphoma Cells

1970 • 101 citations

Cutaneous basophil hypersensitivity

1976 • 100 citations

Mucocutaneous candidiasis, anergy and a plasma inhibitor of cellular immunity: reversal after amphotericin B therapy.

1971 • 98 citations

Immunology of the mycoses. I. Depressed lymphocyte transformation in chronic histoplasmosis.

1968 • 97 citations

Effect of Anticoagulants on Delayed Hypersensitivity Reactions

1967 • 97 citations

Immunologic aspects of Graves' and Hashimoto's diseases

1980 • 97 citations

The fine structure of the vascular response in hapten-specific delayed hypersensitivity and contact dermatitis.

1967 • 95 citations

Cutaneous basophil hypersensitivity. 3. Participation of the basophil in hypersensitivity to antigen-antibody complexes, delayed hypersensitivity and contact allergy. Passive transfer.

1971 • 93 citations

Immune reactivity of leukemia patients to autologous blast cells.

1972 • 88 citations

Delayed-Type Hypersensitivity Skin Reactions in Congenital Afibrinogenemia Lack Fibrin Deposition and Induration

1979 • 87 citations

The effects of anticoagulants and other drugs on cellular and cutaneous reactions to antigen in guinea-pigs with delayed-type hypersensitivity.

1965 • 85 citations

The effect of aging and acute illness on delayed hypersensitivity

1975 • 83 citations

Depression of immunologic reactivity of patients with acute leukemia

1971 • 82 citations

Cellular immune response in coccidioidomycosis

1975 • 81 citations

TUBERCULIN ANERGY AND INFECTIOUS MONONUCLEOSIS

1973 • 81 citations

The histology of the tuberculin reaction and its modification by cortisone.

1951 • 80 citations

The Effect of Carrageenan on Delayed Hypersensitivity Reactions

1969 • 78 citations

Disorders of the Immune System

1967 • 78 citations

Delayed-Hypersensitivity Reactions in Patients with Cancer

1974 • 77 citations

Delayed hypersensitivity in alcoholic cirrhosis

1971 • 76 citations

ELICITATION OF ALLERGIC CONTACT DERMATITIS IN THE GUINEA PIG

1958 • 75 citations

DELAYED HYPERSENSITIVITY RESPONSE TO DNFB IN SICK AND HEALTHY PERSONS*

1964 • 74 citations

Active pulmonary tuberculosis with negative tuberculin skin reactions.

1967 • 73 citations

Decreased Skin-Test Reactivity Associated with Influenza

1972 • 72 citations

Delayed Hypersensitivity Skin Testing. I. Response Rates in a Hospitalized Population

1974 • 72 citations

EPIDEMIOLOGIC STUDIES OF TUBERCULIN SENSITIVITY

1958 • 72 citations

The Current Status of Serologic, Immunologic and Skin Tests in the Diagnosis of Pulmonary Mycoses

1973 • 70 citations

The Effect of Dietary Protein Depletion on Immunocompetence

1974 • 68 citations

Histoplasmin Sensitivity and Coccidioidal Infection

1949 • 64 citations

Spectrum of in vivo and in vitro cell-mediated immune responses in coccidioidomycosis

1977 • 63 citations

Cellular Immunity in Rheumatic Diseases I. Rheumatoid Arthritis

1973 • 62 citations

REGULATION OF DELAYED HYPERSENSITIVITY

1973 • 61 citations

Anergy and skin homograft survival in Hodgkin's disease.

1958 • 60 citations

The pattern of rejection in rat skin homografts, and its relation to the vascular network.

1963 • 60 citations

An electron microscopic study of leukocyte emigration and vascular permeability in tuberculin sensitivity.

1967 • 58 citations

IMMUNITY IN MUMPS

1946 • 58 citations

Immunological skin testing and interpretation. A plea for uniformity

1979 • 58 citations

Cellular Immunity to Nuclear Antigens in Systemic Lupus Erythematosus

1972 • 56 citations

Histology of the tuberculin reaction in guinea‐pigs

1963 • 55 citations

Skin test antigens: an evaluation whose time has come.

1978 • 55 citations

Delayed hypersensitivity in systemic lupus erythematosus.

1968 • 54 citations

The role of cell-mediated immunity in the induction of inflammatory responses. Parke-Davis Award Lecture, 1977.

1977 • 51 citations

The function of macrophages in T-lymphocyte antigen recognition.

1976 • 48 citations

A Histochemical Analysis of Mononuclear Cell Infiltrates of the Skin with Particular Reference to Delayed Hypersensitivity in the Guinea Pig

1966 • 48 citations

Diagnosis of pulmonary coccidioidal infections.

1951 • 46 citations

Correlation of Lymphocyte Transformation with Tuberculin Skin-Test Sensitivity1–3

1973 • 46 citations

A METHOD FOR ESTIMATING THE PREVALENCE OF TUBERCULOUS INFECTION

1975 • 46 citations

Cutaneous Testing in the Elderly Patient with Tuberculosis

1980 • 46 citations

SIMILARITIES BETWEEN HOMOGRAFT REJECTION AND TUBERCULIN-TYPE ALLERGY: A REVIEW OF RECENT EXPERIMENTAL FINDINGS

1957 • 45 citations

Human cell-mediated immunity to tuberculin as assayed by the agarose micro-droplet leukocyte migration inhibition technique: Comparison with the capillary tube assay

1977 • 45 citations

LYMPHOCYTOPENIA IN HODGKIN'S DISEASE.

1965 • 44 citations

Diagnostic and Prognostic Significance of the Quantitative Tuberculin Tests

1967 • 43 citations

Dermal sensitivity to Coccidioides immitis. A comparison of responses elicited in man by spherulin and coccidioidin.

1973 • 43 citations

Mechanisms of reactions in leprosy.

1972 • 43 citations

Dermal Sensitivity to Different Doses of Spherulin and Coccidioidin

1974 • 42 citations

The Effect of Physical and Chemical Properties of the Sensitizing Substance on the Induction and Elicitation of Delayed Contact Sensitivity

1971 • 41 citations

Immunologic Studies in the Lymphoblastomas

1956 • 40 citations

Clinical immunologic responsiveness in malignant disease.I. Delayed hypersensitivity reaction and the effect of cytotoxic drugs

1970 • 40 citations

Anergy in patients with leukocytosis

1974 • 39 citations

The role of cell-mediated immunity in the induction of inflammatory responses

1977 • 37 citations

The Loss of Tuberculin Sensitivity in Certain Patients with Active Pulmonary Tuberculosis

1970 • 36 citations

Role of Immunologic Disturbance in Human Oncogenesis: Some Facts and Fancies

1971 • 35 citations

Recent Advances in Oncology

1972 • 35 citations

Anergy and infection.

1976 • 35 citations

Studies in Myasthenia Gravis

1965 • 35 citations

STUDIES IN IMMUNITY

1935 • 34 citations

SPHERULIN AND COCCIDIOIDIN: CROSS-REACTIONS IN DERMAL SENSITIVITY TO HISTOPLASMIN AND PARACOCCIDIOIDIN

1975 • 34 citations

Effect of BCG on delayed hypersensitivity responses of patients with neoplastic disease

1973 • 34 citations

Delayed hypersensitivity responses of experimental animals to histoplasmin from the yeast and mycelial phases of Histoplasma capsulatum

1978 • 33 citations

Studies in Eczematous Sensitizations

1941 • 33 citations

Depression of established delayed hepersensitivity by mumps virus.

1972 • 33 citations

The Significance of the Lepromin Reaction in Man

2015 • 31 citations

Immune evaluation of lung cancer patients undergoing radiation therapy

1976 • 31 citations

Contact-type delayed hypersensitivity in patients with rheumatoid arthritis

1959 • 30 citations

Histoplasmin-CYL, a yeast phase reagent in skin test studies with humans.

1979 • 30 citations

Reactions Obtained With Transferred Lymphocytes in Patients With Advanced Cancer<xref ref-type="fn" rid="FN2">2</xref>

1965 • 30 citations

Tuberculin Reaction in Cancer Patients, “Mantoux Release,” and Lymphosuppressive-Stimulatory Factors2

1973 • 29 citations

Relationship of Dermal and Pulmonary Sensitivity to Extracts ofCandida albicans1

1971 • 29 citations

Development of sensitivity oto dinitrochlorobenzene in patients with sarcoidosis.

1967 • 29 citations

In vivo and in vitro cell-mediated immunity to tetanus toxoid in adults

1980 • 27 citations

Cellular and molecular events in the delayed-onset hypersensitivities

1978 • 27 citations

Cell-mediated Immunity in Acute Nonlymphocytic Leukemia: Relationship to Host Factors, Therapy, and Prognosis

1974 • 27 citations

The Disk-Tine Tuberculin Test

1961 • 26 citations

Tuberculin sensitivity in elderly patients.

1971 • 25 citations

Suppression of tuberculin skin reactivity by prior tuberculin skin testing.

1975 • 24 citations

Multifaceted Evaluation of Human Tumor Immunity Using a Salt Extracted Colon Carcinoma Antigen

1972 • 24 citations

IMMUNOLOGIC STUDIES OF THYMECTOMIZED AND NONTHYMECTOMIZED PATIENTS WITH MYASTHENIA GRAVIS

1966 • 23 citations

Immune response of patients with rheumatoid arthritis during cyclophosphamide treatment

1973 • 23 citations

Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions.

1975 • 22 citations

The role of cellular immunity in control of neoplasia

1973 • 20 citations

Immunosuppressive factors released by transforming lymphocytes in the delayed hypersensitivity skin response to tuberculin.

1973 • 20 citations

Cell-mediated immunity in systemic lupus erythematosus.

1977 • 19 citations

Cellular hypersensitivity to tuberculin in BCG-revaccinated persons studied by skin reactivity, leucocyte migration inhibition and lymphocyte proliferation.

1980 • 19 citations

Lepromin and Tuberculin Reactivity in Adults not Exposed to Leprosy

1967 • 18 citations

Early recognition and therapy of disseminated coccidioidomycosis

1961 • 18 citations

Experience with the Tuberculin Tine Test in a Sanatorium

1962 • 18 citations

The Effect of Ellagic Acid on Delayed Hypersensitivity Reactions in Guinea Pigs

1971 • 18 citations

BOOSTER EFFECT OF HISTOPLASMIN SKIN TESTING IN AN ELDERLY POPULATION1

1972 • 17 citations

Simultaneous measurements of the accumulation of isotope-labelled protein and erythrocytes in skin reactions of allergic inflammation in the guinea-pig.

1972 • 17 citations

Delayed hypersensitivity and antibody response in rheumatoid arthritis

1964 • 16 citations

PASSIVE TRANSFER OF CONTACT SENSITIVITY BY TRITIATED THYMIDINE-LABELED LYMPHOID CELLS

1963 • 15 citations

TECHNICAL FACTORS AFFECTING THE TUBERCULIN TEST

1937 • 14 citations

Delayed cutaneous hypersensitivity reactions to extracts of human tumors.

1973 • 14 citations

Superficial fungus infections.

1974 • 14 citations

Delayed Hypersensitivity in Graves' Disease1

1974 • 14 citations

The Effect of Fumaropimaric Acid on Delayed Hypersensitivity and Cutaneous Forssman Reactions in the Guinea Pig

1970 • 13 citations

Delayed Hypersensitivity Skin Testing for Assessing Anergy in the Mid-South

1976 • 13 citations

DNCB sensitivity in cancer patients. A review based on sequential testing in 430 patients.

1975 • 13 citations

An evaluation of the peripheral leukocyte migration inhibition test as a correlate of delayed cutaneous hypersensitivity

1976 • 13 citations

A comparison of the heaf and the ‘tine’ disposable multiple puncture tuberculin tests

1964 • 12 citations

Serologic status after positive coccidioidin skin reactions.

1967 • 12 citations

CONTACT HYPERSENSITIVITY, CIRCULATING ANTIBODY, AND IMMUNOLOGIC UNRESPONSIVENESS.

1965 • 12 citations

Cat-scratch skin test antigen: purification by heating.

1977 • 12 citations

Studies in Contact-Dermatitis. IV. The Spontaneous Flare-up of Negative Test-Sites in Experimental Sensitization in Man.

1941 • 12 citations

Secondary delayed type hypersensitivity to sheep red blood cells in mice: Dependence on long-lived memory cells

1979 • 11 citations

Tuberculin Skin Testing in a Chronically Sick Aged Population

1972 • 10 citations

Suppression og the tuberculin reaction by high concentrations of tuberculin and the relationship of this phenomenon to the potency assay of tuberculin.

1967 • 10 citations

Cross reactivity in skin testing with histoplasmin.

1971 • 10 citations

Immune Response in Aged and Young Subjects, following Administration of Large Doses of Tuberculin

1975 • 9 citations

FAILURE OF SKIN TESTING TO DETECT ANTIGEN-ANTIBODY PROPERTIES IN THE TISSUES OF RHEUMATOID ARTHRITIS

1955 • 9 citations

Size of mumps skin test reactions.

1958 • 9 citations

Cutaneous Reactivity in Rheumatic and Nonrheumatic Disease

1967 • 8 citations

Immunological skin testing and interpretation

1980 • 8 citations

Cell mediated immunity to recall antigens in vivo and in vitro

1977 • 7 citations

Leucocyte Migration Inhibition in Behçet’s Disease

1979 • 7 citations

Tuberculin sensitivity in tuberculosis

1971 • 7 citations

THE DISK-TINE TUBERCULIN TEST.

1963 • 7 citations

The tuberculin reaction in hunger cachexia.

1951 • 6 citations

Tuberculin sensitivity in rheumatoid arthritis.

1951 • 6 citations

A micro macrophage migration inhibition test for the detection of cellular immunity in vitro

1979 • 6 citations

Separation of the Major Histocompatibility Antigens from other Antigens Presenton Human Leukemic and White Blood Cell Membranes

2015 • 6 citations

Localization of Complement-fixing Antigens in Cells: Epstein-Barr Virus-induced Membrane and Interior Cell Antigens

1971 • 5 citations

Delayed hypersensitivity reactions in patients with breast cancer.

1978 • 4 citations

Delayed hypersensitivity tests with Mycobacterium leprae purified protein derivative.

1976 • 4 citations

Delayed hypersensitivity skin reactions in the induction phase of remission in acute non lymphoid leukemias.

1978 • 3 citations

SOME CHARACTERISTICS OF A GROUP OF SENIOR CITIZEN VOLUNTEERS FOR PHYSIOLOGICAL STUDIES

1967 • 3 citations

Cat-scratch disease.

1980 • 2 citations

Altered skin reactivity in patients with cancer.

1968 • 2 citations

Lymphocyte Cytotoxicity in Human Acute Leukemia

1974 • 1 citations

Humoral and cell-mediated immune response in systemic lupus erythematosus.

1977 • 1 citations

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