Progesterone as a Bone-Trophic Hormone

Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells

1988 • 1,246 citations

Tetracycline-based histological analysis of bone remodeling

1969 • 1,107 citations

Estrogen Binding, Receptor mRNA, and Biologic Response in Osteoblast-Like Osteosarcoma Cells

1988 • 836 citations

POSTMENOPAUSAL OSTEOPOROSIS

1941 • 822 citations

Decreased Risk of Fractures of the Hip and Lower Forearm with Postmenopausal Use of Estrogen

1980 • 789 citations

Hip Fracture and the Use of Estrogens in Postmenopausal Women

1988 • 627 citations

Growth factors and the regulation of bone remodeling.

1988 • 614 citations

BONE MASS IN POSTMENOPAUSAL WOMEN AFTER WITHDRAWAL OF OESTROGEN/GESTAGEN REPLACEMENT THERAPY

1981 • 593 citations

Postmenopausal Bone Loss Is Prevented by Treatment with Low-Dosage Estrogen with Calcium

1987 • 531 citations

Purification and partial sequence of human osteoclast-activating factor: identity with interleukin 1 beta.

1985 • 505 citations

The menstrual cycle.

1977 • 484 citations

POST-MENOPAUSAL $OElig;STROGENS PROTECT AGAINST FRACTURES OF HIP AND DISTAL RADIUS A Case-control Study

1979 • 459 citations

The cellular basis of bone remodeling: The quantum concept reexamined in light of recent advances in the cell biology of bone

1984 • 404 citations

Altered mineral metabolism in glucocorticoid-induced osteopenia. Effect of 25-hydroxyvitamin D administration.

1979 • 396 citations

Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts.

1986 • 392 citations

Increased Plasma Interleukin-1 Activity in Women After Ovulation

1985 • 349 citations

AN EPIDEMIOLOGIC STUDY OF HIP FRACTURE IN POSTMENOPAUSAL WOMEN

1982 • 341 citations

BONE RESPONSE TO TERMINATION OF ŒSTROGEN TREATMENT

1978 • 329 citations

Progesterone Modulation of Pulsatile Luteinizing Hormone Secretion in Normal Women*

1984 • 316 citations

Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis.

1987 • 303 citations

Concurrent Assays of Circulating Bone Gla-Protein and Bone Alkaline Phosphatase: Effects of Sex, Age, and Metabolic Bone Disease*

1988 • 253 citations

Effect of sex hormones on bone in primary osteoporosis

1969 • 223 citations

Interaction of glucocorticoids with macrophages. Identification of glucocorticoid receptors in monocytes and macrophages.

1978 • 202 citations

Diminished Rates of Bone Formation in Normal Black Adults

1988 • 195 citations

17 beta-estradiol acts directly on the clonal osteoblastic cell line UMR106.

1987 • 180 citations

Stimulation of the proliferation of human bone cells in vitro by human monocyte products with interleukin-1 activity.

1985 • 174 citations

UNCOUPLING OF BONE FORMATION AND RESORPTION BY COMBINED OESTROGEN AND PROGESTAGEN THERAPY IN POSTMENOPAUSAL OSTEOPOROSIS

1985 • 174 citations

Ethinyl Estradiol and Norethindrone in the Treatment of Primary Hyperparathyroidism in Postmenopausal Women

1986 • 172 citations

Glucocorticoid Receptors and Inhibition of Bone Cell Growth in Primary Culture¹²

1977 • 167 citations

Effect of oral 1,25‐dihydroxyvitamin D and calcium on glucocorticoid‐induced osteopenia in patients with rheumatic diseases

1984 • 157 citations

OSTEOPOROSIS AFTER OOPHORECTOMY IN THE MATURE FEMALE RAT AND THE EFFECT OF OESTROGEN AND/OR PROGESTOGEN REPLACEMENT THERAPY IN ITS PREVENTION

1972 • 150 citations

Early effects of ethinyloestradiol and norethisterone treatment in post-menopausal women on bone resorption and calcium regulating hormones

1985 • 150 citations

Prevention of bone mineral loss in postmenopausal women by norethisterone.

1985 • 148 citations

Recovery from Steroid-Induced Osteoporosis

1987 • 141 citations

LOSS OF COMPACT BONE DUE TO MENOPAUSE

1966 • 107 citations

Calcium-Regulating Hormones during the Menstrual Cycle*

1978 • 101 citations

Depo-medroxyprogesterone acetate compared with conjugated estrogens for the treatment of postmenopausal women.

1984 • 95 citations

Vitamin d toxicity complicating the treatment of senile, postmenopausal, and glucocorticoid-induced osteoporosis

1987 • 95 citations

Impaired osteoblast function in osteoporosis: comparison between calcium balance and dynamic histomorphometry.

1984 • 90 citations

Determination of luteal phase length by quantitative basal temperature methods: validation against the midcycle LH peak.

1990 • 77 citations

Effects of Oestrogen and Progestogen Therapy on Calcium Metabolism in Post-Menopausal Women

2015 • 77 citations

Effects of EstrogenIn VivoandIn Vitroon Spontaneous Interleukin-1 Release by Monocytes From Postmenopausal Women*

1989 • 75 citations

Cytoplasmic Glucocorticoid Binding Proteins in Bone Cells

1975 • 71 citations

Effective therapy of glucocorticoid-induced osteoporosis with medroxyprogesterone acetate

1990 • 67 citations

Effect of sex steroids on bone collagen synthesis in vitro

1978 • 62 citations

Influence of estrogen and progesterone on matrix-induced endochondral bone formation

1983 • 62 citations

Oestrogen binding proteins in bone cell cytosol

1978 • 61 citations

Serum Osteocalcin Levels and Bone Alkaline Phosphatase Isoenzyme after Oophorectomy and in Primary Hyperparathyroidism*

1987 • 60 citations

A randomized double‐blind cross‐over trial into the effect of norethisterone on climacteric symptoms and biochemical profiles

1982 • 58 citations

Menstrual cycle changes with marathon training: anovulation and short luteal phase.

1982 • 54 citations

Fluctuation of serum concentration of 1,25-dihydroxyvitamin D3 during the menstrual cycle

1982 • 54 citations

Calcium-Regulating Hormones across the Menstrual Cycle*

1986 • 52 citations

The effects of 17β-estradiol and progestagen on trabecular bone remodeling in oophorectomized dogs

1986 • 51 citations

Effect of the Menstrual Cycle on Calcium-Regulating Hormones in the Normal Young Woman*

1980 • 51 citations

Unchanged biochemical indices of bone turnover despite fluctuations in 1,25-dihydroxyvitamin D during the menstrual cycle

1983 • 49 citations

Steroid Receptors in Osteoblasts

1980 • 48 citations

Effect of megestrol acetate on flushing and bone metabolism in post-menopausal women

1981 • 46 citations

DETECTION OF HIGH-AFFINITY GLUCOCORTICOID BINDING IN RAT BONE

1978 • 46 citations

Glucocorticoids modulate macrophage surface oligosaccharides and their bone binding activity.

1984 • 35 citations

Treatment of Postmenopausal Hyperparathyroidism With Norethindrone

1987 • 34 citations

The comparative effect of ovarian hormone administration on bone mineral status in oophorectomized rats

1989 • 33 citations

Serum bone Gla protein variations during estrogen and calcium prophylaxis of postmenopausal women

1984 • 31 citations

Studies on the antiglucocorticoid action of progesterone in rat thymocytes: Early in vitro effects

1979 • 29 citations

The effect of ovarian sex steroids on bone mineral status in the oöphorectomized rat and in the human.

1978 • 28 citations

Effects of continuous 17β-estradiol administration on the periosteal and corticoendosteal envelope activity in spayed beagles

1987 • 24 citations

Surface activity on the periosteal and corticoendosteal envelopes following continuous progestogen supplementation in spayed Beagles

1986 • 18 citations

The effect of long-term lynestrenol treatment on bone mass in cycling women

1977 • 18 citations

Differences in periosteal and corticoendosteal bone envelope activities in spayed and intact beagles: A histomorphometric study

1985 • 15 citations

Postoophorectomy bone loss is associated with reduced bone Gla protein serum levels: A possible effect of osteoblastic insufficiency

1987 • 14 citations

Studies on osteoporosis X. Effect of estrogen-progestin combination on heparin-induced osteoporosis

1983 • 12 citations

The effect of oestradiol valerate and cyclic oestradiol valerate/DL-norgestrel on calcium metabolism.

1978 • 11 citations

Changes in the bone and liver isoenzymes of alkaline phosphatase in postmenopausal women being treated with norethisterone

1988 • 7 citations