Nuclear Receptors and the Initiation of Thyroid Hormone Action

Familial Syndrome Combining Deaf-Mutism, Stippled Epiphyses, Goiter and Abnormally High PBI: Possible Target Organ Refractoriness to Thyroid Hormone¹²

1967 • 553 citations

The action of thyroid hormones at the cell level

1963 • 526 citations

Tissue Differences in the Concentration of Triiodothyronine Nuclear Binding Sites in the Rat: Liver, Kidney, Pituitary, Heart, Brain, Spleen and Testis

1974 • 469 citations

Ribonucleic acid synthesis during the early action of thyroid hormones

1966 • 400 citations

Thyroid Hormone Action in Cell Culture: Demonstration of Nuclear Receptors in Intact Cells and Isolated Nuclei

1973 • 337 citations

SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY¹

1972 • 336 citations

Role of Plasma Proteins in the Binding, Distribution and Metabolism of the Thyroid Hormones

1968 • 266 citations

Propylthiouracil inhibits the conversion of l-thyroxine to l-triiodothyronine

1972 • 255 citations

Mechanisms of Interaction of a Hormone—Receptor Complex with the Genome of a Eukaryotic Target Cell

1972 • 245 citations

Metabolism of Tissues Excised From Thyroxine-Injected Rats

1952 • 240 citations

Thyroid Hormone Action IN VITRO CHARACTERIZATION OF SOLUBILIZED NUCLEAR RECEPTORS FROM RAT LIVER AND CULTURED GH1 CELLS

1974 • 229 citations

Triiodothyronine Binding to Isolated Liver Cell Nuclei

1975 • 207 citations

A New Radioimmunoassay for Plasma l-Triiodothyronine: Measurements in Thyroid Disease and in Patients Maintained on Hormonal Replacement

1972 • 192 citations

Limited Capacity Binding Sites for l-Triiodothyronine in Rat Liver Nuclei

1973 • 185 citations

Rapid Effects of Single Small Doses of L-Thyroxine and Triiodo-L-thyronine on Growth Hormone, as Studied in the Rat by Radioimmunoassay¹

1975 • 177 citations

Binding of selected iodothyronine analogues to receptor sites of isolated rat hepatic nuclei. High correlation between structural requirements for nuclear binding and biological activity

1975 • 167 citations

Limited Binding Capacity Sites for l-Triiodothyronine in Rat Liver Nuclei

1974 • 160 citations

Determination of Common Parameters of Iodothyronine Metabolism and Distribution in Man by Noncompartmental Analysis

1975 • 138 citations

Thyroid hormone action. Demonstration of similar receptors in isolated nuclei of rat liver and cultured GH1 cells.

1974 • 129 citations

Additive effects of thyroid hormone, growth hormone and testosterone on deoxyribonucleic acid-dependent ribonucleic acid polymerase in rat-liver nuclei

1966 • 119 citations

In vitro binding of L-triiodothyronine to receptors in rat liver nuclei. Kinectics of binding, extraction properties, and lack of requirement for cytosol proteins.

1975 • 115 citations

Quantitative Aspects of Iodothyronine Binding by Cytosol Proteins of Rat Liver and Kidney

1974 • 109 citations

Thyroid hormone action: Stimulation of growth hormone and inhibition of prolactin secretion in cultured GH1 cells

1974 • 106 citations

Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: Possible relationship to hormonal activity

1973 • 100 citations

Specific Triiodothyronine Binding Sites in the Anterior Pituitary of the Rat

1972 • 97 citations

Binding of T₃in Rat Liver Nuclei

1974 • 91 citations

IN VITRODEMONSTRATION OF SPECIFIC TRIIODOTHYRONINE BINDING SITES IN RAT LIVER NUCLEI¹²

1974 • 89 citations

Nuclear Binding Capacity Appears to Limit the Hepatic Response to L-Triiodothyronine (T₃)

1975 • 84 citations

Thyroid Hormone Metabolism

1976 • 72 citations

Comparison of the Metabolism and Distribution of L-Triiodothyronine and Triiodothyroaeetic Acid in the Rat: A Possible Explanation of Differential Hormonal Potency

1976 • 72 citations

Nuclear Triiodothyronine-Binding Protein: Partial Characterization and Binding to Chromatin

1974 • 63 citations

COMPARATIVE EFFECTS OF THYROXINE ANALOGUES IN EXPERIMENTAL ANIMALS*

1960 • 63 citations

Nuclear receptors for thyroid hormone: evidence for nonrandom distribution within chromatin.

1975 • 54 citations

Nicotinamide adenine dinucleotide phosphate-malic enzyme of rat liver. Purification, properties, and immunochemical studies.

1975 • 49 citations

Stimulation by Thyroxine of Amino Acid Incorporation Into Mitochondria

1966 • 39 citations

The Metabolic Significance of Exchangeable Cellular Thyroxine

1969 • 38 citations

THYROXINE STIMULATION OF AMINO ACID INCORPORATION INTO MITOCHONDRIAL PROTEIN: DIFFERENCES BETWEEN IN VIVO AND IN VITRO EFFECTS

1973 • 28 citations

Relative activities of several 3'- and 3':5'-alkyl and aryl thyromimetic agents

1963 • 27 citations