Direct Interaction in T-cells between θPKC and the Tyrosine Kinase p59fyn

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.

1994 • 715 citations

T CELL ANTIGEN RECEPTOR SIGNAL TRANSDUCTION PATHWAYS

1996 • 692 citations

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

1998 • 630 citations

Anchoring proteins for protein kinase C: a means for isozyme selectivity

1998 • 584 citations

Selective modulation of protein kinase C-Θ during T-cell activation

1997 • 558 citations

Protein kinase C isozymes and substrates

1996 • 440 citations

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn)

1991 • 395 citations

A Protein Kinase C Translocation Inhibitor as an Isozyme-selective Antagonist of Cardiac Function

1996 • 371 citations

Signal transduction from multiple Ras effectors

1997 • 308 citations

Protein Kinase C-θ Isoenzyme Selective Stimulation of the Transcription Factor Complex AP-1 in T Lymphocytes

1996 • 251 citations

The Coatomer Protein β′-COP, a Selective Binding Protein (RACK) for Protein Kinase Cε

1997 • 251 citations

Interaction of protein kinase C ζ with ZIP, a novel protein kinase C-binding protein

1997 • 214 citations

Regulation of the Inositol 1,4,5-Trisphosphate Receptor by Tyrosine Phosphorylation

1996 • 212 citations

Regulation of Lymphocyte Function by Protein Phosphorylation

1993 • 203 citations

Anchoring proteins for protein kinase C: a means for isozyme selectivity

1998 • 194 citations

Analysis of the Role of Protein Kinase C-α, -ε, and -ζ in T Cell Activation

1995 • 184 citations

Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif

1994 • 179 citations

Direct Interaction between Protein Kinase Cθ (PKCθ) and 14-3-3τ in T Cells: 14-3-3 Overexpression Results in Inhibition of PKCθ Translocation and Function†

1996 • 158 citations

Wiskott–Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

1996 • 154 citations

LEUKOCYTE PROTEIN TYROSINE KINASES:Potential Targets for Drug Discovery

1997 • 144 citations

Activators of Protein Kinase C Induce Dissociation of CD4, But Not CD8, from p56 ^lck

1989 • 111 citations

Modulating Protein Kinase C Signal Transduction

1998 • 105 citations

Structure and expression of Ick transcripts in human lymphoid cells

1988 • 104 citations

The HIV Nef Protein Associates with Protein Kinase C Theta

1996 • 100 citations

Interactions between Protein Kinase C and Pleckstrin Homology Domains

1997 • 97 citations

Interleukin-4 and its receptor: Essential mediators of the allergic response

1997 • 95 citations

Structural and Thermodynamic Characterization of the Interaction of the SH3 Domain from Fyn with the Proline-Rich Binding Site on the p85 Subunit of PI3-Kinase

1996 • 94 citations

T-Cell Antigen Receptor-Induced Signal-Transduction Pathways. Activation and Function of Protein Kinases C in T Lymphocytes

1995 • 83 citations

Specific Association of Tyrosine-phosphorylated c-Cbl with Fyn Tyrosine Kinase in T Cells

1996 • 75 citations

A Physical Interaction between the Cell Death Protein Fas and the Tyrosine Kinase p59

1996 • 73 citations

CD43-specific Activation of T Cells Induces Association of CD43 to Fyn Kinase

1996 • 72 citations

Camptothecin Sensitivity Is Mediated by the Pleiotropic Drug Resistance Network in Yeast

1997 • 69 citations

Differential requirement of protein tyrosine kinases and protein kinase C in the regulation of T cell locomotion in three-dimensional collagen matrices.

1997 • 69 citations

Different Protein Kinase C Isoenzymes Regulate IL-2 Receptor Expression or IL-2 Synthesis in Human Lymphocytes Stimulated via the TCR

1998 • 68 citations

Interleukin‐7 activates p56^lck and p59^fyn, two tyrosine kinases associated with the p90 interleukin‐7 receptor in primary human T cells

1995 • 62 citations

New Perspectives on PKCθ, a Member of the Novel Subfamily of Protein Kinase C

1998 • 59 citations

An SH3-binding Site Conserved in Bruton's Tyrosine Kinase and Related Tyrosine Kinases Mediates Specific Protein Interactions in Vitro and in Vivo

1995 • 55 citations

Human T lymphocyte activation induces tyrosine phosphorylation of α‐tubulin and its association with the SH2 domain of the p59^fyn protein tyrosine kinase

1995 • 50 citations

Physical and functional interactions of protein tyrosine kinases, p59fyn and ZAP-70, in T cell signaling.

1996 • 46 citations

Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells.

1996 • 45 citations

Unique Catalytic Properties Dictate the Enhanced Function of p59^fynT, the Hemopoietic Cell-Specific Isoform of the Fyn Tyrosine Protein Kinase, in T cells

1994 • 34 citations

Protein affinity map of chemical space

1998 • 28 citations

Human p59fyn(T) regulates OKT3-induced calcium influx by a mechanism distinct from PIP2 hydrolysis in Jurkat T cells.

1995 • 23 citations