Overexpression of Collagen XVIII Is Associated with Poor Outcome and Elevated Levels of Circulating Serum Endostatin in Non–Small Cell Lung Cancer

Revisions in the International System for Staging Lung Cancer

1997 • 4,582 citations

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Clinical Applications of Research on Angiogenesis

1995 • 2,300 citations

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

1997 • 1,705 citations

Secreted cathepsin L generates endostatin from collagen XVIII

2000 • 459 citations

Collagen XVIII Is a Basement Membrane Heparan Sulfate Proteoglycan

1998 • 335 citations

Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene

1999 • 301 citations

The generation of endostatin is mediated by elastase.

1999 • 295 citations

The Short and Long Forms of Type XVIII Collagen Show Clear Tissue Specificities in Their Expression and Location in Basement Membrane Zones in Humans

1998 • 252 citations

Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases

2000 • 226 citations

Isolation and sequencing of cDNAs for proteins with multiple domains of Gly-Xaa-Yaa repeats identify a distinct family of collagenous proteins.

1994 • 190 citations

Mouse endostatin inhibits the formation of lung and liver metastases.

1999 • 152 citations

Elevated levels of circulating plasma matrix metalloproteinase 9 in non-small cell lung cancer patients.

1999 • 114 citations

Serum endostatin levels are elevated in patients with soft tissue sarcoma

2001 • 97 citations

Tumor progression is associated with a significant decrease in the expression of the endostatin precursor collagen XVIII in human hepatocellular carcinomas.

2001 • 81 citations

Serum endostatin correlates with progression and prognosis of non-small cell lung cancer

2002 • 78 citations

Prospective analysis of circulating endostatin levels in patients with renal cell carcinoma

2002 • 69 citations

Serum levels of endostatin and matrix metalloproteinase-9 associated with high stage and grade primary transitional cell carcinoma of the bladder

2003 • 63 citations

A Prospective Analysis of Plasma Endostatin Levels in Colorectal Cancer Patients With Liver Metastases

2001 • 62 citations

Effect of endostatin on spontaneous tumorigenesis of mammary adenocarcinoma in a transgenic mouse model.

2000 • 58 citations

Serum endostatin predicts tumor vascularity in hepatocellular carcinoma

2002 • 56 citations

Correlation between serum vascular endothelial growth factor and endostatin levels in patients with breast cancer

2003 • 50 citations

Circulating angiogenic cytokines as tumour markers and prognostic factors in head and neck squamous cell carcinoma

2002 • 45 citations

Biomarkers of Intrinsic Angiogenic and Anti-angiogenic Activity in Patients with Endometrial Hyperplasia and Endometrial Cancer

2001 • 39 citations

Human endostatin inhibits growth of human non-small-cell lung cancer in a murine xenotransplant model

2001 • 30 citations

Increased expression of collagen XVIII and its prognostic value in nonsmall cell lung carcinoma

2004 • 27 citations

Collagen type XVIII/endostatin is differentially expressed in primary and metastatic colorectal cancers and ovarian carcinomas

2001 • 20 citations

Expression of the Endostatin gene in epithelial ovarian cancer.

2001 • 20 citations