Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo

Normal Table of Xenopus Laevis (Daudin)

1958 • 4,561 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

1998 • 1,048 citations

A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway

1997 • 861 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

Midbrain development induced by FGF8 in the chick embryo

1996 • 734 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesisy

1998 • 693 citations

Xenopus embryos regulate the nuclear localization of XMyoD.

1994 • 648 citations

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1994 • 484 citations

Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase.

1989 • 442 citations

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

1992 • 438 citations

The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions

1995 • 435 citations

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

1992 • 414 citations

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

1995 • 390 citations

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.

1993 • 348 citations

eFGF regulates Xbra expression during Xenopus gastrulation.

1994 • 340 citations

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain

1997 • 326 citations

Caudalization of neural fate by tissue recombination and bFGF

1995 • 290 citations

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus

1996 • 285 citations

Mesoderm formation in response to Brachyury requires FGF signalling

1995 • 276 citations

Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication

1994 • 267 citations

Phospholipase C-γ as a Signal-Transducing Element

1999 • 242 citations

Mesoderm induction in Xenopus caused by activation of MAP kinase

1995 • 223 citations

Fibroblast growth factor receptors have different signaling and mitogenic potentials

1994 • 214 citations

Involvement of p21ras in Xenopus mesoderm induction

1992 • 207 citations

bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus

1995 • 203 citations

Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF

1993 • 199 citations

TGF-β signals and a prepattern in Xenopus laevis endodermal development

1996 • 196 citations

Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3

1998 • 190 citations

Efficient Hormone-Inducible Protein Function in Xenopus laevis

1995 • 190 citations

TheXenopus Brachyurypromoter is activated by FGF and low concentrations ofactivinandsuppressed by high concentrationsof activin and by paired-type homeodomain proteins

1997 • 183 citations

Spatial response to fibroblast growth factor signalling inXenopusembryos

1999 • 165 citations

VERTEBRATE NEURAL INDUCTION

1997 • 162 citations

Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.

1994 • 156 citations

Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development

1995 • 155 citations

Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg

1992 • 154 citations

Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1

1994 • 142 citations

Promiscuity of fibroblast growth factor receptors

1996 • 140 citations

Signal Transduction Pathway of Human Fibroblast Growth Factor Receptor 3

1997 • 139 citations

Fibroblast growth factor receptors have different signaling and mitogenic potentials.

1994 • 136 citations

Involvement of the MAP kinase cascade in Xenopus mesoderm induction.

1995 • 136 citations

Regulation of the fibroblast growth factor receptor in early Xenopus embryos.

1990 • 135 citations

A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis

1997 • 134 citations

Fibroblast growth factor receptors display both common and distinct signaling pathways.

1995 • 125 citations

Analysis of competence and of Brachyury autoinduction by use of hormoneinducible Xbra

1997 • 121 citations

Shc and a Novel 89-kDa Component Couple to the Grb2-Sos Complex in Fibroblast Growth Factor-2-stimulated Cells

1995 • 114 citations

Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras.

1996 • 102 citations

Localization of MAP Kinase Activity in EarlyXenopusEmbryos: Implications for Endogenous FGF Signaling

1997 • 93 citations

cDNA cloning and developmental expression of fibroblast growth factor receptors from Xenopus laevis.

1991 • 87 citations

Conditional Transformation of Cells and Rapid Activation of the Mitogen-Activated Protein Kinase Cascade by An Estradiol-Dependent Human Raf-1 Protein Kinase

1993 • 86 citations

Prepattern in the developing Drosophila eye revealed by an activated torso--sevenless chimeric receptor.

1992 • 80 citations

Dorsal-Ventral Differences in Xcad-3 Expression in Response to FGF-Mediated Induction in Xenopus

1994 • 78 citations

Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells

1999 • 78 citations

Spatially restricted expression of fibroblast growth factor receptor-2 during Xenopus development

1992 • 57 citations

Direct Activation of Phospholipase C-γ by Fibroblast Growth Factor Receptor Is Not Required for Mesoderm Induction in Xenopus Animal Caps

1994 • 37 citations

Amino acid residues which distinguish the mitogenic potentials of two FGF receptors

1997 • 32 citations

Mesoderm Induction by Heterodimeric AP-1 (c-Jun and c-Fos) and Its Involvement in Mesoderm Formation through the Embryonic Fibroblast Growth Factor/Xbra Autocatalytic Loop during the Early Development of Xenopus Embryos

1998 • 27 citations

Expression of tenascin mRNA in mesoderm during Xenopus lævis embryogenesis: the potential role of mesoderm patterning in tenascin regionalization

1992 • 19 citations

Cloning of cDNA and genomic DNA encoding fibroblast growth factor receptor-4 of xenopus laevis

1995 • 15 citations

Early Regionalized Expression of a NovelXenopusFibroblast Growth Factor Receptor in Neuroepithelium

1996 • 14 citations

Upstream and downstream from Brachyury, a gene required for vertebrate mesoderm formation.

1997 • 14 citations

Role of fibroblast growth factor during early midbrain development in Xenopus

1998 • 11 citations

Control of somitic expression of tenascin in Xenopus embryos by myogenic factors and Brachyury

1994 • 6 citations