Divergent evolution in M6P/IGF2R imprinting from the Jurassic to the Quaternary

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

1991 • 904 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture

2001 • 832 citations

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

1993 • 602 citations

Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.

1994 • 593 citations

Imprinted expression of the Igf2r gene depends on an intronic CpG island

1997 • 578 citations

Genomic imprinting and the strange case of the insulin-like growth factor II receptor

1991 • 494 citations

Mouse Mutants Lacking the Type 2 IGF Receptor (IGF2R) Are Rescued from Perinatal Lethality inIgf2andIgf1rNull Backgrounds

1996 • 479 citations

Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene

1994 • 471 citations

Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis

2000 • 393 citations

A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate

1988 • 363 citations

M6P/IGF2R Imprinting Evolution in Mammals

2000 • 266 citations

The insulin–like growth factor type–2 receptor gene is imprinted in the mouse but not in humans

1993 • 238 citations

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

1993 • 228 citations

Genomic imprinting is disrupted in interspecific Peromyscus hybrids

1998 • 186 citations

Allelic expression of IGF2 in marsupials and birds

2000 • 177 citations

Obstetric outcome of singleton pregnancies after IVF: a matched control study in four Dutch university hospitals

2000 • 174 citations

Encyclopedia of Molecular Biology

2002 • 152 citations

Chicken and Xenopus Mannose 6-Phosphate Receptors Fail to Bind Insulin-like Growth Factor II

1989 • 137 citations

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice

2001 • 130 citations

Monotreme IGF2 expression and ancestral origin of genomic imprinting

2001 • 129 citations

Genomic Imprinting and Cancer

2006 • 128 citations

The imprinting box of the mouse Igf2r gene

1999 • 121 citations

Conservation of a maternal-specific methylation signal at the human IGF2R locus

1995 • 116 citations

Marsupials and Eutherians reunited: genetic evidence for the Theria hypothesis of mammalian evolution

2001 • 96 citations

Imprint status of M6P/IGF2R and IGF2 in chickens

2001 • 84 citations

Human insulin-like growth factor type I and type II receptors are not imprinted

1993 • 78 citations

Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor

1997 • 70 citations

Tissue-Specific Imprinting of the Mouse Insulin-Like Growth Factor II Receptor Gene Correlates with Differential Allele-Specific DNA Methylation

1998 • 57 citations

Allelic IGF2R Repression Does Not Correlate with Expression of Antisense RNA in Human Extraembryonic Tissues

2001 • 51 citations

Imprinted M6p/Igf2 receptor is mutated in rat liver tumors

1998 • 47 citations

Imprinted genes as potential genetic and epigenetic toxicologic targets.

2000 • 41 citations

Genomic structure of the human M6P/IGF2 receptor

1999 • 41 citations

Insulin-like growth factor II receptor, transforming growth factor-β, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis

1998 • 36 citations

Improving the polymorphism content of the 3′ UTR of the human IGF2R gene

1992 • 34 citations

Characterization of mannose 6-phosphate receptors (MPRs) from opossum liver: opossum cation-independent MPR binds insulin-like growth factor-II.

1993 • 33 citations

Polymorphisms, genomic imprinting and cancer susceptibility

1999 • 31 citations

Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations

2001 • 31 citations

The Kangaroo Cation-independent Mannose 6-Phosphate Receptor Binds Insulin-like Growth Factor II with Low Affinity

1999 • 28 citations

Liver regeneration and carcinogenesis : molecular and cellular mechanisms

1995 • 21 citations

Analysis and Identification of Imprinted Genes

1998 • 20 citations

Making Sense of Imprinting the Mouse and Human IGF2R Loci

2007 • 18 citations

Dinucleotide repeat polymorphism at the IGF2R locus

1992 • 18 citations

Mechanisms of liver tumor promotion

1995 • 18 citations