Endothelin-1 Secretion by Alveolar Macrophages in Systemic Sclerosis

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

1980 • 4,703 citations

Polar secretion of endothelin-1 by cultured endothelial cells.

1992 • 650 citations

Endothelins, peptides with potent vasoactive properties, are produced by human macrophages.

1990 • 462 citations

Transforming growth factor-β stimulates the expression of endothelin mRNA by vascular endothelial cells

1989 • 420 citations

Evidence for Chronic Inflammation as a Component of the Interstitial Lung Disease Associated with Progressive Systemic Sclerosis

1985 • 310 citations

Expression of endothelin-1 in lungs of patients with cryptogenic fibrosing alveolitis

1993 • 284 citations

Circulating endothelin-1 levels in systemic sclerosis subsets--a marker of fibrosis or vascular dysfunction?

1994 • 240 citations

Evaluation and management of scleroderma lung disease using bronchoalveolar lavage

1990 • 236 citations

Endothelin, an endothelial‐dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action

1991 • 228 citations

Endothelins and the lung.

1996 • 196 citations

Significance of plasma endothelin-1 levels in patients with systemic sclerosis.

1992 • 158 citations

Potent stimulation of monocytic endothelin-1 production by HIV-1 glycoprotein 120.

1993 • 150 citations

Specific Binding of Endothelin on Human Bronchial Smooth Muscle Cells in Culture and Secretion of Endothelin-like Material from Bronchial Epithelial Cells

1990 • 140 citations

Distribution of Endothelin-like Immunoreactivity and mRNA in the Developing and Adult Human Lung

1991 • 136 citations

Increased levels of endothelin-1 in bronchoalveolar lavage fluid from patients with systemic sclerosis contribute to fibroblast mitogenic activity in vitro.

1994 • 133 citations

Plasma endothelin-1 levels, pulmonary hypertension, and lung fibrosis in patients with systemic sclerosis

1995 • 104 citations

Increased endothelin-1 production in fibroblasts derived from patients with systemic sclerosis.

1994 • 100 citations

Endothelin-1 in idiopathic pulmonary fibrosis.

1995 • 100 citations

Increased Endothelin-Like Immunoreactive Material on Bronchoalveolar Lavage Fluid from Patients with Bronchial Asthma and Patients with Interstitial Lung Disease

1993 • 59 citations

Human Cultured Endothelial Cells Do Secrete Endothelin-1

1989 • 57 citations

SPONTANEOUS PRODUCTION OF FIBRONECTIN BY ALVEOLAR MACROPHAGES IN PATIENTS WITH SCLERODERMA

1989 • 50 citations

Interleukin 6 secretion by monocytes and alveolar macrophages in systemic sclerosis with lung involvement.

1994 • 47 citations

Elevated plasma endothelin levels in systemic sclerosis

1995 • 44 citations

Subcutaneous administration of hyaluronan reduces the number of infectious exacerbations in patients with chronic bronchitis.

1996 • 40 citations

Interleukin-8 and neutrophils in systemic sclerosis with lung involvement.

1994 • 38 citations

Involvement of endothelin in mononuclear phagocyte inflammation in asthma

1996 • 35 citations

Sandwich-Enzyme Immunoassays for Endothelin Family Peptides

1991 • 30 citations

Enzyme immunometric assay for endothelin using tandem monoclonal antibodies

1993 • 26 citations

Radioimmunoassay of immunoreactive C-terminal big-endothelin(22-38).

1991 • 21 citations

Impaired Growth Response to Endothelin-1 in Scleroderma Fibroblasts

1995 • 18 citations

Increased plasma endothelin-1 immunoreactive levels in vasculitis

1993 • 16 citations

Sandwich-type enzyme immunoassay for big endothelin-1 in plasma: concentrations in healthy human subjects unaffected by sex or posture

1997 • 15 citations

Critical evaluation of endothelins assay.

1994 • 9 citations