Hyperplasia of Smooth Muscle in Mild to Moderate Asthma without Changes in Cell Size or Gene Expression

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The unbiased estimation of number and sizes of arbitrary particles using the disector

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The Mechanics of Airway Narrowing in Asthma

1989 • 805 citations

Airway Structural Alterations Selectively Associated with Severe Asthma

2003 • 784 citations

Cellular Hypertrophy and Hyperplasia of Airway Smooth Muscles Underlying Bronchial Asthma: A 3-D Morphometric Study

1993 • 625 citations

Airway Smooth Muscle Cell Proliferation Is Increased in Asthma

2001 • 508 citations

Functional significance of increased airway smooth muscle in asthma and COPD

1993 • 494 citations

The isector: a simple and direct method for generating isotropic, uniform random sections from small specimens

1992 • 296 citations

Spectroscopy of defects in germanium-doped silica glass

1993 • 276 citations

A theoretical analysis of the effect of airway smooth muscle load on airway narrowing.

1996 • 264 citations

Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects.

1995 • 251 citations

Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects

2002 • 251 citations

Markers of airway smooth muscle cell phenotype

1996 • 232 citations

Lung morphometry: a new generation of tools and experiments for organ, tissue, cell, and molecular biology

1993 • 226 citations

Guidelines for the Diagnosis and Management of Asthma: Update on Selected Topics 2002

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Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes

1999 • 176 citations

Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects

1994 • 158 citations

The contribution of airway smooth muscle to airway narrowing and airway hyperresponsiveness in disease

2000 • 141 citations

Structural and Functional Changes in the Airway Smooth Muscle of Asthmatic Subjects

1998 • 131 citations

Serum deprivation induces a unique hypercontractile phenotype of cultured smooth muscle cells

1998 • 131 citations

Airway muscle stereology: implications for increased shortening in asthma.

1996 • 124 citations

Hypothesis: excessive bronchoconstriction in asthma is due to decreased airway elastance

1994 • 121 citations

Phenotypic diversity and molecular mechanisms of airway smooth muscle proliferation in asthma

2000 • 119 citations

Airway smooth muscle in health and disease; methods of measurement and relation to function

2000 • 95 citations

A Novel Method of Gene Transcript Profiling in Airway Biopsy Homogenates Reveals Increased Expression of a Na⁺-K⁺-Cl⁻ Cotransporter (NKCC1) in Asthmatic Subjects

2001 • 92 citations

WW-781, a potent reversible inhibitor of red cell Cl- flux, binds to band 3 by a two-step mechanism

1993 • 76 citations

Repeated allergen inhalation induces phenotypic modulation of smooth muscle in bronchioles of sensitized rats

2003 • 67 citations

Airway Smooth Muscle in Health and Disease

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Increased amount of airway smooth muscle does not account for excessive bronchoconstriction in asthma.

1998 • 24 citations

Allergen challenge causes inflammation but not goblet cell degranulation in asthmatic subjects

2001 • 22 citations