Transgene Expression of bcl-xL Permits Anti-immunoglobulin (Ig)–induced Proliferation in xid B Cells

Cancer Cell Cycles

1996 • 5,379 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

1993 • 1,438 citations

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

1993 • 1,338 citations

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

1995 • 1,167 citations

Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice

1993 • 868 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

1992 • 766 citations

Defective B cell development and function in Btk-deficient mice

1995 • 729 citations

Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis

1996 • 661 citations

Colocalization of X-Linked Agammaglobulinemia and X-Linked Immunodeficiency Genes

1993 • 631 citations

Apoptosis and the cell cycle

1995 • 334 citations

Impaired expansion of mouse B cell progenitors lacking Btk

1995 • 314 citations

Peritoneal Ly‐1 B cells: Genetic control, autoantibody production, increased lambda light chain expression

1986 • 306 citations

The CBA/N Mouse Strain: An Experimental Model Illustration the Influence of the X-Chromosome on Immunity

1982 • 305 citations

Cyclin dependent kinase regulation

1995 • 286 citations

Mutations in the Mu Heavy-Chain Gene in Patients with Agammaglobulinemia

1996 • 258 citations

bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.

1996 • 178 citations

Monoclonal antibodies to murine CD40 define two distinct functional epitopes

1994 • 152 citations

An embryonic source of Ly1 but not conventional B cells

1991 • 145 citations

Cells en route to apoptosis are characterized by the upregulation of c‐fos, c‐myc, c‐jun, cdc2, and RB phosphorylation, resembling events of early cell‐cycle traverse

1995 • 144 citations

Demonstration of B-cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescence

1983 • 133 citations

Roles of IGH and L Chains and of Surrogate H and L Chains in the Development of Cells of the B Lymphocyte Lineage

1994 • 124 citations

Frequent Aberrant Immunoglobulin Gene Rearrangements in Pro-B Cells Revealed by a bcl-x Transgene

1996 • 120 citations

Identification of DNA-replicating lymphocyte subsets using a new method to label the bromo-deoxyuridine incorporated into the DNA

1992 • 118 citations

An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis.

1996 • 117 citations

Regulation of Growth and Proliferation in B Cell Subpopulations

1982 • 112 citations

Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes.

1996 • 110 citations

Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset of B lymphocytes.

1978 • 100 citations

X‐Linked Agammaglobulinemia: New Approaches to Old Questions based on the Identification of the Defective Gene

1994 • 86 citations

Human B‐Cell Development

1995 • 73 citations

Regulation of B cell survival in xid mice by the proto-oncogene bcl-2.

1996 • 65 citations

Profound reduction of mature B cell numbers, reactivities and serum lg levels in mice which simultaneously carry the XID and CD40 deficiency gense

1996 • 44 citations

Surface Markers, Heavy Chain Sequences and B Cell Lineages

1992 • 40 citations

Expression of bcl‐x during mouse B cell differentiation and following activation by various stimuli

1996 • 39 citations

Genetic Analysis of Tyrosine Kinase Function in B Cell Development

1996 • 34 citations

CD40 signaling induces interleukin‐4‐independent IgE switching in vivo

1996 • 31 citations

Biochemical analysis of the immune B cell defect in xid mice.

1991 • 26 citations

Apoptosis in hematopoietic cells is associated with an extensive decrease in cellular phosphotyrosine content that can be inhibited by the tyrosine phosphatase antagonist pervanadate

1996 • 15 citations

Are xid B lymphocytes representative of any normal B cell population. A commentary.

1985 • 6 citations