Metabolism and Distribution of [2,3-¹⁴C]Acrolein in Sprague-Dawley Rats

Cyclophosphamide cystitis—Identification of acrolein as the causative agent

1979 • 568 citations

Cyclophosphamide Toxicity

1991 • 401 citations

Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide.

1979 • 189 citations

The role of acrolein in allyl alcohol-induced lipid peroxidation and liver cell damage in mice

1987 • 122 citations

The biotransformation of allyl alcohol and acrolein in rat liver and lung preparations.

1980 • 107 citations

Conversion of allyl alcohol into acrolein by rat liver

1972 • 95 citations

Biosynthesis of mercapturic acids from allyl alcohol, allyl esters and acrolein

1973 • 88 citations

Urinary metabolites of [1,2,3-13C]acrylonitrile in rats and mice detected by carbon-13 nuclear magnetic resonance spectroscopy

1991 • 75 citations

Acrolein Mercapturates: Synthesis, Characterization, and Assessment of Their Role in the Bladder Toxicity of Cyclophosphamide

1995 • 63 citations

Hepatotoxicity of cyclophosphamide in man: pharmacokinetic analysis.

1988 • 55 citations

3‐Hydroxypropylmercapturic acid: A biologic marker of exposure to allylic and related compounds

1989 • 54 citations

Nephrotoxicity of the 1:1 acrolein-glutathione adduct in the rat

1992 • 52 citations

Identification of urinary mercapturic acids formed from acrylate, methacrylate and crotonate in the rat

1981 • 50 citations

Studies on the in vivo formation of acrolein: 3-hydroxy-propylmercapturic acid as an index of cyclophosphamide (NSC-26271) activation.

1976 • 50 citations

Some aspects of the persistence and fate of acrolein herbicide in water

1977 • 50 citations

Studies on the Basis for the Toxicity of Acrolein Mercapturates

1996 • 48 citations

The disposition and metabolism of acrylic acid and ethyl acrylate in male Sprague-Dawley rats*1

1987 • 48 citations

Biotransformation of Acrolein in Rat: Excretion of Mercapturic Acids after Inhalation and Intraperitoneal Injection

1996 • 45 citations

Metabolism and Distribution of [2,3-14C]Acrolein in Sprague-Dawley Rats

1996 • 45 citations

A new pathway of acrolein metabolism in rats

1983 • 45 citations

Allyl alcohol- and acrolein-induced toxicity in isolated rat hepatocytes

1989 • 44 citations

Two‐year toxicity and carcinogenicity study of acrolein in rats

1992 • 42 citations

Ethyl acrylate distribution, macromolecular binding, excretion, and metabolism in male Fisher 344 rats

1987 • 38 citations

Acute toxicity of fluorinated ether anesthetics: Role of 2,2,2-trifluoroethanol and other metabolites

1983 • 37 citations

Bioactivation mechanism of S-(3-oxopropyl)-N-acetyl-L-cysteine, the mercapturic acid of acrolein

1992 • 35 citations

Identification and comparison of the urinary metabolites of [1,2,3-13C3]acrylic acid and [1,2,3-13C3]propionic acid in the rat by homonuclear 13C nuclear magnetic resonance spectroscopy.

1992 • 34 citations

Rat urinary bladder epithelial lesions induced by acrolein.

1989 • 32 citations

The Metabolism of Crotyl Phosphate, Crotyl Alcohol and Crotonaldehyde

1971 • 32 citations

ANALYSIS OF BEER CARBONYLS AT THE PART PER BILLION LEVEL BY COMBINED LIQUID CHROMATOGRAPHY AND HIGH PRESSURE LIQUID CHROMATOGRAPHY

1981 • 31 citations

Loss of acrolein from water by volatilization and degradation

1974 • 26 citations

Mutagenic Activity of Acrolein inS. typhimurium andE. coli

1996 • 25 citations

Volatile components of raw chicken breast muscle

1967 • 24 citations

Analysis of acrolein in aged aqueous media. Comparison of various analytical methods with bioassays

1978 • 23 citations

Oncogenicity Study of Acrolein in Mice

1991 • 22 citations

Determination of acrolein in urine by liquid chromatography and fluorescence detection of its quinoline derivative.

1993 • 22 citations

Developmental Toxicity of Acrolein in New Zealand White Rabbits

1993 • 22 citations

Gene mutation assay of acrolein in the CHO/HGPRT test system

1991 • 22 citations

The Biosynthesis of 3-Hydroxypropylmercapturic Acid from Cyclophosphamide

1979 • 21 citations

One‐year toxicity of orally administered acrolein to the beagle dog

1992 • 20 citations

Reproductive study of acrolein on two generations of rats

1992 • 20 citations

The mobility and degradation of acrolein in agricultural canals treated with magnacide® H herbicide

1996 • 20 citations

Identification and quantitative determination of four different mercapturic acids formed from 1,3-dibromopropane and its 1,1,3,3-tetradeutero analogue by the rat

1986 • 19 citations

Interaction of cyclophosphamide metabolites with membrane proteins: An in vitro study with rabbit liver microsomes and human red blood cells

1982 • 16 citations

Acrolein for the Control of Water Weeds and Disease-Carrying Water Snails

1959 • 16 citations

FIELD TRIALS IN EGYPT WITH ACROLEIN HERBICIDE-MOLLUSCICIDE.

1965 • 16 citations

Acrolein as a Possible Metabolite of Cyclophosphamide in Man

1974 • 15 citations

Effect of Magnacide ® H Herbicide Residuals on Water Quality Within Wildlife Refuges of the Klamath Basin, CA

1996 • 13 citations

Possible role of acrolein in 4-hydroperoxycyclophosphamide-induced cell damage in vitro.

1991 • 12 citations