Evidence synthesis combining individual patient data and aggregate data: a systematic review identified current practice and possible methods

Meta-analysis in clinical trials

1986 • 36,193 citations

Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease

1959 • 14,850 citations

Beta blockade during and after myocardial infarction: An overview of the randomized trials

1985 • 3,248 citations

Systematic Reviews in Health Care : Meta-Analysis in Context

2000 • 2,282 citations

Methods for Meta-Analysis in Medical Research

2000 • 1,803 citations

Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials

2000 • 1,789 citations

QUANTITATIVE METHODS IN THE REVIEW OF EPIDEMIOLOGIC LITERATURE1

1987 • 1,619 citations

Systematic Reviews in Health Care. Meta-analysis in Context.

2002 • 1,441 citations

Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis

2000 • 943 citations

MTHFR 677C→T Polymorphism and Risk of Coronary Heart Disease

2002 • 934 citations

Meta‐Analysis Of Controlled Clinical Trials

2002 • 811 citations

Meta-analysis of the literature or of individual patient data: is there a difference?

1993 • 752 citations

Effect of lipid reduction on the progression of renal disease: A meta-analysis

2001 • 669 citations

Neoadjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis

2003 • 623 citations

Patient age and outcome following severe traumatic brain injury: an analysis of 5600 patients

2003 • 612 citations

Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials

1997 • 580 citations

Laparoscopic surgery for inguinal hernia repair: systematic review of effectiveness and economic evaluation

2005 • 572 citations

Meta-analysis of individual patient data from randomized trials: a review of methods used in practice

2005 • 522 citations

To IPD or not to IPD?

2002 • 511 citations

Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status

2003 • 499 citations

Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: An overview of 6,633 patients from 27 randomized trials

1998 • 486 citations

Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. Myeloma Trialists' Collaborative Group.

1998 • 429 citations

Repair of Groin Hernia With Synthetic Mesh

2002 • 393 citations

A comparison of summary patient-level covariates in meta-regression with individual patient data meta-analysis

2002 • 378 citations

Meta-analysis of randomised adjuvant therapy trials for pancreatic cancer

2005 • 355 citations

Follow-up strategies for women treated for early breast cancer

2016 • 332 citations

Infrared ear thermometry compared with rectal thermometry in children: a systematic review

2002 • 314 citations

Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis

2001 • 293 citations

Open Mesh versus non-Mesh for groin hernia repair

2001 • 278 citations

Early supported discharge services for stroke patients: a meta-analysis of individual patients' data

2005 • 268 citations

A multilevel model framework for meta-analysis of clinical trials with binary outcomes

2000 • 259 citations

Individual Patient Cohort Analysis of the Efficacy of Hypertonic Saline/Dextran in Patients with Traumatic Brain Injury and Hypotension

1997 • 240 citations

Prognosis of vertebrobasilar transient ischaemic attack and minor stroke

2003 • 217 citations

Primary coronary angioplasty compared with intravenous thrombolytic therapy for acute myocardial infarction: Six-month follow up and analysis of individual patient data from randomized trials

2003 • 198 citations

Duration and intensity of maintenance chemotherapy in acute lymphoblastic leukaemia: overview of 42 trials involving 12 000 randomised children

1996 • 183 citations

Individual participant data meta-analyses compared with meta-analyses based on aggregate data

2016 • 164 citations

Factors affecting uptake of childhood immunisation: a Bayesian synthesis of qualitative and quantitative evidence

2002 • 164 citations

Laparoscopic versus open groin hernia repair: meta-analysis of randomised trials based on individual patient data

2002 • 162 citations

Improving ecological inference using individual‐level data

2005 • 161 citations

Reporting of prognostic markers: current problems and development of guidelines for evidence-based practice in the future

2003 • 159 citations

Investigating heterogeneity in an individual patient data meta-analysis of time to event outcomes

2005 • 158 citations

The therapy of amblyopia: an analysis of the results of amblyopia therapy utilizing the pooled data of published studies.

1998 • 158 citations

Selegiline for Alzheimer's disease

2003 • 157 citations

Systematic reviews of the effectiveness of day care for people with severe mental disorders: (1) Acute day hospital versus admission; (2) Vocational rehabilitation; (3) Day hospital versus outpatient care

2001 • 157 citations

Impact of shared epitope genotype and ethnicity on erosive disease: A meta‐analysis of 3,240 rheumatoid arthritis patients

2004 • 149 citations

Dipyridamole for Preventing Recurrent Ischemic Stroke and Other Vascular Events

2004 • 140 citations

Meta-Analysis Using Multilevel Models with an Application to the Study of Class Size Effects

2000 • 130 citations

Prognostic models based on literature and individual patient data in logistic regression analysis

2000 • 91 citations

Meta‐analysis of ordinal outcomes using individual patient data

2001 • 89 citations

Multilevel models for meta-analysis, and their application to absolute risk differences

2001 • 85 citations

Recursive Cumulative Meta-analysis

1999 • 82 citations

Efficacy of acupuncture in asthma: systematic review and meta-analysis of published data from 11 randomised controlled trials

2002 • 81 citations

Particular HLA–DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis

2004 • 78 citations

Observations in anticoagulant and thrombolytic therapy in pulmonary embolism

1975 • 73 citations

Effect of active compression–decompression resuscitation (ACD-CPR) on survival: a combined analysis using individual patient data

1999 • 55 citations

The Value of the Aggregate Data Approach in Meta-Analysis with Time-to-Event Outcomes

2001 • 51 citations

Predictive modeling and heterogeneity of baseline risk in meta-analysis of individual patient data

2001 • 48 citations

Lack of association of the HLA–DRB1 shared epitope with rheumatoid nodules: An individual patient data meta‐analysis of 3,272 Caucasian patients with rheumatoid arthritis

2004 • 30 citations

Multilevel models for meta-analysis, and their application to absolute risk differences

2001 • 29 citations

Bayesian Methods for the Cross-Design Synthesis of Epidemiological and Toxicological Evidence

2004 • 27 citations

Estimates of the effect on hepatic iron of oral deferiprone compared with subcutaneous desferrioxamine for treatment of iron overload in thalassemia major: a systematic review

2002 • 26 citations

From science to practice. Meta-analyses using individual patient data are needed

1995 • 24 citations

[Unresected colorectal liver metastases: prognostic value of laboratory variables].

2001 • 6 citations

Are trials with individual patient data available different from trials without individual patient data available?

2001 • 4 citations

P126 Including literature data in individual patient data meta-analyses for time-to-event endpoints

1997 • 3 citations