α-Conotoxin EpI, a Novel Sulfated Peptide from Conus episcopatusThat Selectively Targets Neuronal Nicotinic Acetylcholine Receptors

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Rapid analysis of amino acids using pre-column derivatization

1984 • 2,491 citations

Presynaptic nicotinic ACh receptors

1997 • 1,313 citations

Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction

1981 • 1,044 citations

Low access resistance perforated patch recordings using amphotericin B

1991 • 935 citations

Observations on the isolated phrenic nerve diaphragm preparation of the rat

1997 • 618 citations

OBSERVATIONS ON THE ISOLATED PHRENIC NERVE DIAPHRAGM PREPARATION OF THE RAT

1946 • 581 citations

A New α-Conotoxin Which Targets α3β2 Nicotinic Acetylcholine Receptors

1996 • 479 citations

Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function.

1997 • 431 citations

Peptide toxins from Conus geographus venom.

1981 • 238 citations

Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes.

1997 • 210 citations

Isolation and structure of a peptide toxin from the marine snail Conus magus

1982 • 194 citations

α-Conotoxin MII Blocks Nicotine-Stimulated Dopamine Release in Rat Striatal Synaptosomes

1997 • 189 citations

Conus peptides as chemical probes for receptors and ion channels

1993 • 183 citations

A nicotinic acetylcholine receptor ligand of unique specificity, alpha-conotoxin ImI

1994 • 183 citations

alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors.

1995 • 151 citations

Novel .alpha.- and .omega.-conotoxins and Conus striatus venom

1992 • 138 citations

Biological mass spectrometry

1991 • 136 citations

Protein tyrosine sulfation

1987 • 135 citations

Acetylcholine‐evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia.

1991 • 130 citations

Neuronal Nicotinic Acetylcholine Receptors on Bovine Chromaffin Cells: Cloning, Expression, and Genomic Organization of Receptor Subunits

1997 • 130 citations

A New Family of Conus Peptides Targeted to the Nicotinic Acetylcholine Receptor

1995 • 123 citations

Heterogeneity of Nicotinic Receptor Class and Subunit mRNA Expression among Individual Parasympathetic Neurons from Rat Intracardiac Ganglia

1997 • 122 citations

A new neurotoxin receptor site on sodium channels is identified by a conotoxin that affects sodium channel inactivation in molluscs and acts as an antagonist in rat brain.

1994 • 122 citations

Bromocontryphan: Post-Translational Bromination of Tryptophan

1997 • 118 citations

In Vitro Methods For Studying Secretion

1987 • 117 citations

Determinants of Specificity for α-Conotoxin MII on α3β2 Neuronal Nicotinic Receptors

1997 • 115 citations

New Consensus Features for Tyrosine O-Sulfation Determined by Mutational Analysis

1997 • 112 citations

New Mollusk-Specific .alpha.-Conotoxins Block Aplysia Neuronal Acetylcholine Receptors

1994 • 106 citations

A Novel Post-translational Modification Involving Bromination of Tryptophan

1997 • 99 citations

Phylogenetic specificity of cholinergic ligands: .alpha.-conotoxin SI

1988 • 98 citations

.alpha.-Conotoxin EI, A New Nicotinic Acetylcholine Receptor Antagonist with Novel Selectivity

1995 • 96 citations

The 1.1 å crystal structure of the neuronal acetylcholine receptor antagonist, α-conotoxin PnIA from Conus pennaceus

1996 • 86 citations

Mechanisms of Activation of Muscle Nicotinic Acetylcholine Receptors and the Time Course of Endplate Currents

1995 • 82 citations

Crystal Structure at 1.1 Å Resolution of α-Conotoxin PnIB: Comparison with α-Conotoxins PnIA and GI

1997 • 76 citations

Direct recording of nicotinic responses in presynaptic nerve terminals.

1997 • 76 citations

Color test for terminal prolyl residues in the solid-phase synthesis of peptides

1980 • 71 citations

Analysis of sequence requirements for protein tyrosine sulfation

1993 • 70 citations

Natural and synthetic neurotoxins

1993 • 70 citations

Differential expression of alpha-bungarotoxin-sensitive neuronal nicotinic receptors in adrenergic chromaffin cells: a role for transcription factor Egr-1.

1997 • 67 citations

Direct Recording of Nicotinic Responses in Presynaptic Nerve Terminals

1997 • 67 citations

alpha-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors.

1995 • 66 citations

Determinants Involved in the Affinity of α-Conotoxins GI and SI for the Muscle Subtype of Nicotinic Acetylcholine Receptors

1997 • 59 citations

Differential Expression of α-Bungarotoxin-Sensitive Neuronal Nicotinic Receptors in Adrenergic Chromaffin Cells: A Role for Transcription Factor Egr-1

1997 • 58 citations

Regions of β4·β2 subunit chimeras that contribute to the agonist selectivity of neuronal nicotinic receptors

1992 • 54 citations

Local anaesthetic blockade of neuronal nicotinic ACh receptor‐channels in rat parasympathetic ganglion cells

1994 • 38 citations

Evaluation of the Final Deprotection System for the Solid-Phase Synthesis of Tyr(SO3H)-Containing Peptides with 9-Fluorenylmethyloxycarbonyl (Fmoc)-Strategy and Its Application to the Synthesis of Cholecystokinin (CCK)-12.

1993 • 36 citations

Vasoactive intestinal polypeptide modulation of nicotinic ACh receptor channels in rat intracardiac neurones.

1996 • 31 citations

Degradation of human gastrin and CCK by endopeptides 24.11: differential behaviour of the sulphated and unsulphated peptides

1989 • 19 citations

α-Conotoxin GI produces tetanic fade at the rat neuromuscular junction

1992 • 16 citations

Qualitative analysis in peptide synthesis: an improved method for proline residues

1986 • 3 citations