CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α (PPARα) in mice

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

Molecular Bases for Circadian Clocks

1999 • 2,823 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

2002 • 2,248 citations

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

1998 • 1,954 citations

Resetting of Circadian Time in Peripheral Tissues by Glucocorticoid Signaling

2000 • 1,733 citations

Mutagenesis and Mapping of a Mouse Gene, Clock , Essential for Circadian Behavior

1994 • 1,570 citations

mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

1999 • 1,558 citations

Extensive and divergent circadian gene expression in liver and heart

2002 • 1,498 citations

Molecular Analysis of Mammalian Circadian Rhythms

2001 • 1,428 citations

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

1999 • 1,260 citations

A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock

1999 • 894 citations

A transcription factor response element for gene expression during circadian night

2002 • 852 citations

Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

2002 • 785 citations

The basic-helix–loop–helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors

1998 • 761 citations

Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus

2002 • 701 citations

Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2

1999 • 668 citations

NPAS2: An Analog of Clock Operative in the Mammalian Forebrain

2001 • 555 citations

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity

2002 • 529 citations

Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts

2000 • 478 citations

Molecular Mechanisms of the Biological Clock in Cultured Fibroblasts

2001 • 465 citations

Regulation of CLOCK and MOP4 by Nuclear Hormone Receptors in the Vasculature

2001 • 442 citations

CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP

2000 • 418 citations

Altered Patterns of Sleep and Behavioral Adaptability in NPAS2-Deficient Mice

2003 • 413 citations

Genome-wide Expression Analysis of Mouse Liver Reveals CLOCK-regulated Circadian Output Genes

2003 • 347 citations

Expression of the Peroxisome Proliferator-activated Receptor α Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

1996 • 317 citations

Rad23 Promotes the Targeting of Proteolytic Substrates to the Proteasome

2002 • 293 citations

Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock

2000 • 270 citations

Histone Acetyltransferase-dependent Chromatin Remodeling and the Vascular Clock

2004 • 203 citations

Molecular analysis of zebrafish photolyase/cryptochrome family: two types of cryptochromes present in zebrafish

2000 • 200 citations

CLIF, a Novel Cycle-like Factor, Regulates the Circadian Oscillation of Plasminogen Activator Inhibitor-1 Gene Expression

2000 • 200 citations

Angiotensin II Induces Circadian Gene Expression of Clock Genes in Cultured Vascular Smooth Muscle Cells

2001 • 182 citations

Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2

2003 • 155 citations

Dexamethasone and Insulin Demonstrate Marked and Opposite Regulation of the Steady‐State mRNA Level of the Peroxisomal Proliferator‐Activated Receptor (PPAR) in Hepatic Cells

1994 • 143 citations

Rhythmic Expression of BMAL1 mRNA Is Altered in Clock Mutant Mice: Differential Regulation in the Suprachiasmatic Nucleus and Peripheral Tissues

2000 • 143 citations

Disturbances in the normal regulation of SREBP-sensitive genes in PPARα-deficient mice

2001 • 140 citations

Peroxisome Proliferator-activated Receptor α (PPARα) Turnover by the Ubiquitin-Proteasome System Controls the Ligand-induced Expression Level of Its Target Genes

2002 • 138 citations

Rhythmic expression of NocturninmRNA in multiple tissues of the mouse

2001 • 113 citations

Identification of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Target Genes in Mouse Liver Using cDNA Microarray Analysis

2001 • 111 citations

Microarray Analysis of Gene Expression Changes in Mouse Liver Induced by Peroxisome Proliferator- Activated Receptor α Agonists

2002 • 110 citations

Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding

2004 • 102 citations

Functional CLOCK is not involved in the entrainment of peripheral clocks to the restricted feeding: entrainable expression of mPer2 and BMAL1 mRNAs in the heart of Clock mutant mice on Jcl:ICR background

2002 • 93 citations

Circadian clock and microarrays: mammalian genome gets rhythm

2002 • 91 citations

Circadian Transcription

2002 • 84 citations

Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts

2004 • 61 citations

Signaling to the Mammalian Circadian Clocks: In Pursuit of the Primary Mammalian Circadian Photoreceptor

2001 • 46 citations

The Circadian E-Box: When Perfect Is Not Good Enough

2003 • 46 citations

CIRCADIAN CLOCKS: WHAT MAKES THEM TICK?

2000 • 39 citations

Tissue-specific augmentation of circadian PAI-1 expression in mice with streptozotocin-induced diabetes

2004 • 36 citations

Circadian Rhythm Biochemistry: From Protein Degradation to Sleep and Mating

2001 • 24 citations

Sex difference in circadian period of body temperature in Clock mutant mice with Jcl/ICR background

2003 • 22 citations