Methylphenidate elevates resting dopamine which lowers the impulse-triggered release of dopamine: a hypothesis

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Dopamine (3-hydroxytyramine) and brain function.

1966 • 1,401 citations

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

1995 • 857 citations

Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry

1988 • 663 citations

Relationship between subjective effects of cocaine and dopamine transporter occupancy

1997 • 653 citations

Is Methylphenidate Like Cocaine?

1995 • 575 citations

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain

1994 • 473 citations

A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis

1987 • 404 citations

Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis

1989 • 402 citations

Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys.

1989 • 389 citations

Cloning and functional characterization of a cocaine‐sensitive dopamine transporter

1991 • 362 citations

SPECT imaging of striatal dopamine release after amphetamine challenge.

1995 • 330 citations

Endogenous dopamine lowers the dopamine D₂ receptor density as measured by [³H]raclopride: Implications for positron emission tomography of the human brain

1989 • 298 citations

Extracellular Concentration and In Vivo Recovery of Dopamine in the Nucleus Accumbens Using Microdialysis

1992 • 278 citations

Regulation of transient dopamine concentration gradients in the microenvironment surrounding nerve terminals in the rat striatum

1992 • 258 citations

Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen.

1989 • 236 citations

Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux.

1995 • 182 citations

PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjects

1997 • 151 citations

Effects of cocaine and related drugs in nonhuman primates. II. Stimulant effects on schedule-controlled behavior.

1989 • 149 citations

In vivo neurochemical profile of dopamine uptake inhibitors and releasers in rat caudate-putamen

1989 • 139 citations

Dopamine D2 receptor binding sites for agonists. A tetrahedral model.

1985 • 132 citations

Effects of d-amphetamine and dopamine synthesis inhibitors on dopamine and acetylcholine neurotransmission in the striatum. I. Release in the absence of vesicular transmitter stores.

1986 • 132 citations

ENHANCEMENT BY RESERPINE AND ALPHA-METHYL DOPA OF THE EFFECTS OF D-AMPHETAMINE UPON THE LOCOMOTOR ACTIVITY OF MICE.

1963 • 122 citations

Central monoamines and hyperkinesis of childhood

1976 • 106 citations

Chronic cocaine alters limbic extracellular dopamine. Neurochemical basis for addiction

1992 • 99 citations

Attenuation of hyperactivity in the spontaneously hypertensive rat by amphetamine

1982 • 96 citations

Effects ofd-amphetamine and methylphenidate on hyperactivity produced by neonatal 6-hydroxydopamine treatment

1989 • 96 citations

Characterisation of methylphenidate and nomifensine induced dopamine release in rat striatum using in vivo brain microdialysis

1991 • 87 citations

2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters

1997 • 77 citations

Assessment of endogenous dopamine release by methylphenidate challenge using iodine-123 iodobenzamide single-photon emission tomography

1997 • 76 citations

Does amphetamine preferentially increase the extracellular concentration of dopamine in the mesolimbic system of freely moving rats?

1990 • 75 citations

Stereoselective disposition of methylphenidate in children with attention-deficit disorder.

1987 • 68 citations

Role of vesicular dopamine in the in vivo stimulation of striatal dopamine transmission by amphetamine: Evidence from microdialysis and Fos immunohistochemistry

1995 • 62 citations

Nitrogen-based drugs are not essential for blockade of monoamine transporters

1996 • 61 citations

The Dopamine Transporter Carboxyl-terminal Tail

1996 • 57 citations

Intranigral administration of D2 dopamine receptor antisense oligodeoxynucleotides establishes a role for nigrostriatal D2 autoreceptors in the motor actions of cocaine.

1994 • 56 citations

Interaction between Ethanol and Dextroamphetamine: Effects on Psychomotor Performance

1992 • 49 citations

Amphetamine-induced hypolocomotion in mice with more brain D2 dopamine receptors

1982 • 44 citations

Pharmacology of electrically evoked dopamine release studied in the rat olfactory tubercle by in vivo electrochemistry

1989 • 38 citations

Amphetamine inhibits the electrically evoked release of [3H]dopamine from slices of the rabbit caudate.

1983 • 35 citations

Exogenous tyrosine potentiates the methylphenidate-induced increase in extracellular dopamine in the nucleus accumbens: a microdialysis study

1991 • 32 citations

De la potentialisation des effets de la DOPA par les inhibiteurs de la monoamineoxydase

1966 • 30 citations

Differences between (+)- and (?)-amphetamine in effects on locomotor activity and l-dopa potentiating action in mice

1975 • 23 citations

Dopamine Agonist‐Induced Inhibition of Neurotransmitter Release from the Awake Squirrel Monkey Putamen as Measured by Microdialysis

1997 • 16 citations

Effects of drugs, age and illumination on response speed of squirrel monkeys

1986 • 5 citations