Genetic Time-series Analysis Identifies a Major QTL for in vivo Alcohol Metabolism not Predicted by in vitro Studies of Structural Protein Polymorphism at the ADH1B or ADH1C Loci

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1990 • 463 citations

Combined Linkage and Association Sib-Pair Analysis for Quantitative Traits

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Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an american indian population

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Heterochromatin Effects on the Frequency and Duration of LCR-Mediated Gene Transcription

1996 • 328 citations

Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism

1995 • 314 citations

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A Global Perspective on Genetic Variation at the ADH Genes Reveals Unusual Patterns of Linkage Disequilibrium and Diversity

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Genetic polymorphism of alcohol dehydrogenase in europeans: TheADH2*2 allele decreases the risk for alcoholism and is associated withADH3*1

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Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism

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Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family

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Polymorphism of ADH and ALDH Genes among Four Ethnic Groups in China and Effects upon the Risk for Alcoholism

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An improved multipoint sib-pair analysis of quantitative traits

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Alcohol Dehydrogenase Polymorphisms Influence Alcohol‐Elimination Rates in a Male Jewish Population

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1985 • 141 citations

Kinetic and electrophoretic properties of native and recombined isoenzymes of human liver alcohol dehydrogenase

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Association of GABRG3 With Alcohol Dependence

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Developmental regulation of human β-globin gene transcription: a switch of loyalties?

1993 • 100 citations

chi-ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: implications and inferences.

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Studies on the subunit structure and molecular size of the human alcohol dehydrogenase isozymes determined by the different loci, ADH₁ADH₂, and ADH₃

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Polymorphism of the human alcohol dehydrogenase 4 (ADH4) promoter affects gene expression

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Exploring Positional Candidate Genes: Linkage Conditional on Measured Genotype

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Factor and simplex models for repeated Measures: Application to two psychomotor measures of alcohol sensitivity in twins

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The human class I alcohol dehydrogenase gene cluster: Three genes are tandemly organized in an 80-kb-long segment of the genome

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Alcohol Consumption and Alcohol Pharmacokinetics: Interactions Within the Normal Population

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Bias toward the Null Hypothesis in Model-Free Linkage Analysis Is Highly Dependent on the Test Statistic Used

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Genomic Structure and Expression of the ADH7 Gene Encoding Human Class IV Alcohol Dehydrogenase, the Form Most Efficient for Retinol Metabolism in Vitro

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Possible epistatic role of ADH7 in the protection against alcoholism

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Untitled

1999 • 34 citations

Variation in Alcohol Pharmacokinetics as a Risk Factor for Alcohol Dependence

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The use of 5-hydroxytryptophol as an alcohol intake marker.

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Chromosomal assignment of the alcohol dehydrogenase cluster locus to human chromosome 4q21–23 by in situ hybridization

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Inherent Bias toward the Null Hypothesis in Conventional Multipoint Nonparametric Linkage Analysis

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A Retroviral Repetitive Element Confers Tissue-Specificity to the Human Alcohol Dehydrogenase 1C (ADH1C) Gene

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Multivariate QTL analysis using structural equation modeling: A look at power under simple conditions

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Tissue-Specific Regulatory Elements in the Human Alcohol Dehydrogenase 6 Gene

2000 • 12 citations