Functional anatomy of germinal centers

THE FUNCTIONS OF THE THYMUS SYSTEM AND THE BURSA SYSTEM IN THE CHICKEN

1966 • 779 citations

Surface Antigen Expression and Immunoglobulin Gene Rearrangement During Mouse pre‐B Cell Development

1983 • 490 citations

The Follicular Dendritic Cell: Its Role in Antigen Presentation in the Generation of Immunological Memory

1980 • 490 citations

Immunohistologic analysis of the organization of normal lymphoid tissue and non-Hodgkin's lymphomas.

1980 • 432 citations

Distribution of T cell subsets in human lymph nodes.

1981 • 420 citations

The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.

1981 • 389 citations

Antigens in Immunity

1966 • 372 citations

Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation.

1982 • 320 citations

Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. I. T cells derived from Peyer's patches that switch sIgM B Cells to sIgA B cells in vitro

1983 • 287 citations

The distribution, ontogeny and origin in the rat of Ia‐positive cells with dendritic morphology and of Ia antigen in epithelia, with special reference to the intestine

1983 • 274 citations

Peanut lectin binding properties of germinal centers of mouse lymphoid tissue

1980 • 259 citations

Stages of B cell differentiation in human lymphoid tissue.

1981 • 241 citations

The generation of memory cells. I. The role of C3 in the generation of B memory cells.

1977 • 235 citations

Germinal centre B cells: antigen specificity and changes in heavy chain class expression

1982 • 220 citations

Complement Dependence of Localisation of Aggregated IgG in Germinal Centres

1975 • 210 citations

Lymphoid tissue architecture. Experimental analysis of the origin and distribution of T-cells and B-cells.

1972 • 203 citations

CELL PROLIFERATION IN GERMINAL CENTERS OF THE RAT SPLEEN*

1964 • 192 citations

ANTIGENS IN IMMUNITY

1964 • 174 citations

Effect of thymus cell injections on germinal center formation in lymphoid tissues of nude (thymusless) mice

1974 • 168 citations

Marginal zones: the major B cell compartment of rat spleens

1981 • 163 citations

Migrant μ⁺δ⁺ and static μ⁺δ⁻ B lymphocyte subsets

1982 • 159 citations

Germinal center B cells lack homing receptors necessary for normal lymphocyte recirculation.

1983 • 157 citations

The lymphocytes of splenic marginal zones: a distinct B-cell lineage

1982 • 143 citations

AN AUTORADIOGRAPHIC STUDY OF THE GERMINAL CENTER IN SPLEEN WHITE PULP DURING EARLY INTERVALS OF THE IMMUNE RESPONSE.

1964 • 141 citations

Fluorescence analysis and anatomic distribution of mouse T lymphocyte subsets defined by monoclonal antibodies to the antigens Thy-1, Lyt-1, Lyt-2, and T-200.

1981 • 141 citations

SOME HISTOLOGICAL AND FUNCTIONAL ASPECTS OF LYMPHOID TISSUE IN GERMFREE ANIMALS: I. MORPHOLOGICAL STUDIES*

1959 • 138 citations

Studien über Regeneration der Gewebe

1884 • 135 citations

SPECIFIC ANTIBODY WITHIN LYMPHOID GERMINAL CENTER CELLS OF MICE AFTER PRIMARY IMMUNIZATION WITH HORSERADISH PEROXIDASE: A LIGHT AND ELECTRON MICROSCOPIC STUDY

1970 • 117 citations

ANATOMICAL DISTRIBUTION OF T AND B LYMPHOCYTES IN THE RAT

1973 • 113 citations

Über die Bildung der Lymphocyten in Lymphdrüsen und Milz

1912 • 111 citations

Germinal centres and the origin of the B-cell system. II. Germinal centres in the rabbit spleen and popliteal lymph nodes.

1974 • 107 citations

The localization of non-microbial antigens in the draining lymph nodes of tolerant, normal and primed rabbits.

1967 • 104 citations

Mouse lymph node germinal centers contain a selected subset of T cells--the helper phenotype.

1982 • 88 citations

Binding of peanut lectin to thymic cortex and germinal centres of lymphoid tissue.

1981 • 77 citations

Long-term antigen retention by dendritic cells in the popliteal lymph node of immunized mice.

1981 • 72 citations

Early and Enhanced Germinal Center Formation and Antibody Responses in Mice after Primary Stimulation with Antigen-Isologous Antibody Complexes as Compared with Antigen Alone

1971 • 64 citations

Monoclonal antibodies to B cells

1983 • 62 citations

Immunohistochemical identification of T- and B-lymphocytes delineated by the unlabeled antibody enzyme method. I. Anatomical distribution of Ω-positive and Ig-positive cells in lymphoid organs of mice

1976 • 61 citations

Antigens, lymphoid cells, and the immune response

1971 • 60 citations

Localization of Afferent Lymph Cells within the Draining Node during a Primary Immune Response

1970 • 58 citations

THE RETICULO-ENDOTHELIAL SYSTEM

1926 • 57 citations

Reactivity of presumed anti-natural killer cell antibody Leu 7 with intrafollicular T lymphocytes.

1983 • 51 citations

Effect of Antigen Dose on Lymphatic Tissue Germinal Center Changes.

1966 • 51 citations

Physiology of IgD. I. Compensatory phenomena in B lymphocyte activation in mice treated with anti-IgD antibodies.

1981 • 50 citations

Germinal centres and the origin of the B-cell system. I. Germinal centres in the rabbit appendix.

1974 • 50 citations

Lymphoid Tissue Architecture. III. Germinal Centers, T Cells, and Thymus-Dependent vs Thymus-Independent Antigens

1976 • 48 citations

Complement Receptor Subtypes C3b and C3d in Lymphatic Tissue and Follicular Lymphoma

1978 • 48 citations

Cell Production and Cell Migration in the Tonsil

1967 • 47 citations

RELATIONSHIP OF GERMINAL CENTERS IN LYMPHOID TISSUE TO IMMUNOLOGICAL MEMORY

1968 • 46 citations

An immunohistochemical study of cells with surface and cytoplasmic immunoglobulins in situ in Peyer’s patches and lamina propria of rat small intestine

1982 • 45 citations

The cellular basis of immunological recovery in nude mice after thymus grafting.

1974 • 45 citations

Bursa of Fabricius as Site of Origin of Germinal Centre Cells

1972 • 44 citations

Antigens in the spleen. The non-specificity of the follicles in the process of antigen trapping and the role of antibody.

1972 • 42 citations

B-cell differentiation in vivo

1981 • 42 citations

Electron Microscopic Studies of Germinal Centers in Man

1967 • 40 citations

Die Gefässversorgung der Malpighischen Körperchen in der Milz

1928 • 37 citations

Site of initiation of the plasma cell reaction in the rabbit lymph node

1978 • 36 citations

RELATIONSHIP OF GERMINAL CENTERS IN LYMPHOID TISSUE TO IMMUNOLOGICAL MEMORY

1968 • 35 citations

Kinetics of Cellular Death in Germinal Centers of Mouse Spleen

1967 • 35 citations

Germinal centres and the B-cell system. V

1981 • 33 citations

B lymphocyte differentiation in lethally irradiated and reconstituted mice

1978 • 31 citations

The Role of Germinal Centres in the Generation of Immunological Memory

1981 • 30 citations

Identification of cells expressing T and p28,33 (Ia-like) antigens in sections of human lymphoid tissue.

1980 • 29 citations

Role of C3 in the regulation of a splenic PFC response in rabbits.

1980 • 28 citations

The distribution of cells expressing a natural killer cell marker (HNK-1) in normal human lymphoid organs and malignant lymphomas

1983 • 28 citations

The development of specific antibody‐containing cells and the localization of extracellular antibody in the follicles of the spleen of rabbits after administration of free or liposome‐associated albumin antigen

1983 • 28 citations

Lymph macrophages enter the germinal center of lymph nodes of guinea pigs

1977 • 27 citations

The Integrity of the Germinal Center: An Investigation of the Differential Localization of Labeled Cells in Lymphoid Organs

1967 • 26 citations

AN ULTRASTRUCTURAL STUDY ON ANTIBODY PRODUCTION OF THE LYMPH NODES OF RATS WITH SPECIAL REFERENCE TO THE ROLE OF GERMINAL CENTERS

1977 • 26 citations

HOMING OF BONE MARROW LYMPHOID CELLS

1978 • 25 citations

Migratory patterns of B lymphocytes

1975 • 25 citations

The Still Unsolved Germinal Centre Mystery (Invited Lecture)

1976 • 24 citations

Germinal centre proliferation in response to mitogenic lymphokines.

1974 • 24 citations

Immunohistochemical identification of T- and B-lymphocytes delineated by the unlabelled antibody enzyme method

1981 • 24 citations

INNUNOCYTOLOGICAL STUDIES ON THE CONSTITUENT CELLS OF THE SECONDARY NODULES IN HUMAN TONSILS

1980 • 22 citations

ASSOCIATION OF T CELLS WITH PROLIFERATING CELLS IN LYMPHOID FOLLICLES

1981 • 22 citations

Effects of neonatal anti-delta antibody treatment on the murine immune system. I. Suppression of development of surface IgD+ B cells and expansion of a surface IgM+ IgD- B lymphocyte population.

1983 • 20 citations

Germinal centers and the B-cell system

1981 • 20 citations

Differentiation Pathway within Germinal Centers of Human Tonsils

1969 • 20 citations

Involvement of thymus cells in the formation of germinal centers

1974 • 18 citations

Germinal centres and the B cell system

1980 • 17 citations

Reassortment of Cell Populations within the Lymphoid Apparatus of the Sheep

1980 • 17 citations

Cell population kinetics of the germinal centres of lymph nodes of BALB/c mice.

1980 • 16 citations

Histophysiology of Follicular Structures and Germinal Centres in Relation to B Cell Differentiation

1981 • 16 citations

Germinal Centres and the B-Cell System: A Search for the Germinal Centre Precursor Cell in the Rat

1979 • 16 citations

The Concept of the ‘Centron’

1965 • 15 citations

Terminal galactosyl residues of cell-surface glycoconjugates exposed on both human and murine immature T- and B-cells

1981 • 15 citations

Binding of peanut lectin to lymphocytes: a marker of immaturity?

1982 • 15 citations

Surface Phenotype and Migratory Capability of Peyer’s Patch Germinal Center Cells

1982 • 15 citations

Histophysiology of Normal Lymphoid Tissue and Immune Reactions

1980 • 14 citations

Radiosensitivity of the Antigen-Trapping Mechanism and its Relation to the Suppression of Immune Response

1969 • 14 citations

Histological Changes of Lymphoid Tissues in Relation to the Ontogeny of the Immune Response in Germfree Piglets

1971 • 14 citations

A Comparative Study of the Immune Reaction in Germfree and Conventional Mice

1969 • 13 citations

Antigen modulation of the immune response

1980 • 13 citations

Homing of germinal-center cells into germinal centers of lymph node via afferent lymphatics

1984 • 13 citations

Distribution of IgM- and IgG-containing cells during the primary immune response in the rat spleen

1982 • 13 citations

Effects of antigen dosage on early localization of specific antibodies in rat splenic germinal centers

1980 • 12 citations

Expression of T Cell Antigens by Cells in Mouse and Human Primary and Secondary Follicles

1982 • 12 citations

Germinal centers and the B-cell system

1982 • 10 citations

Germinal Centers and the B Cell System VIII. Functional Characteristics and Cell Surface Markers of Germinal Center Cell Subsets Differing in Density and in Sedimentation Velocity

1983 • 10 citations

Maturity of Precursor Cells for Germinal Centers

1982 • 9 citations

Migratory Patterns of the Ly Subsets of T Lymphocytes in the Mouse

1979 • 9 citations

Separation and Characterization of Tonsillar Germinal Centre Lymphocytes Using Peanut Lectin

1982 • 6 citations

IgG-Fc and C3 receptors in the chicken: distribution, tissue localization and functional significance

1982 • 5 citations

Immunoperoxidase Analysis of B and T Cell Populations in Human Lymphoid Follicles

1982 • 5 citations

Histologic Localization of Hemolysin-Containing Cells

1969 • 4 citations

MICROSCOPIC AND ELECTRON MICROSCOPIC DISTRIBUTION OF ANTIGEN IN LYMPHOID ORGANS

1971 • 4 citations