Prenatal exposure to morphine enhances cocaine and heroin self-administration in drug-naive rats

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Opiate Receptor: Demonstration in Nervous Tissue

1973 • 2,364 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

[Drug addiction and drug abuse].

1969 • 1,466 citations

Factors That Predict Individual Vulnerability to Amphetamine Self-Administration

1989 • 1,354 citations

The pharmacology of cocaine related to its abuse.

1989 • 685 citations

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

1984 • 644 citations

Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration

1990 • 574 citations

Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems

1982 • 560 citations

Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

1977 • 490 citations

Characteristics of the “Receptor” for Narcotic Analgesics in Synaptic Plasma Membrane Fraction from Rat Brain

1973 • 426 citations

Response to novelty predicts the locomotor and nucleus accumbens dopamine response to cocaine

1991 • 292 citations

The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat

1987 • 281 citations

Anatomically Distinct Opiate Receptor Fields Mediate Reward and Physical Dependence

1984 • 265 citations

Individual reactivity to novelty predicts probability of amphetamine self-administration

1990 • 255 citations

Reinforcing properties of ejaculation in the male rat: Role of opioids and dopamine.

1990 • 239 citations

Theory in Psychopharmacology

1982 • 229 citations

Effect of early and later colony housing on oral ingestion of morphine in rats

1981 • 227 citations

The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat

1990 • 223 citations

Involvement of opioid and dopaminergic systems in isolation-induced pinning and social grooming of young rats

1989 • 217 citations

Mesolimbicocortical dopamine terminal fields are necessary for normal locomotor and investigatory exploration in rats

1980 • 212 citations

Neuroanatomical focus for morphine and enkaphalin-induced hypermotility

1977 • 209 citations

Ontological development of opiate receptors in rodent brain

1976 • 193 citations

The role of dopamine in intracranial self-stimulation of the ventral tegmental area

1987 • 189 citations

Experimental approach to individual vulnerability to psychostimulant addiction

1989 • 180 citations

Methadone Maintenance Treatment

1985 • 177 citations

β-Endorphin and male sexual behavior

1977 • 171 citations

Effect of naltrexone on alcohol consumption during chronic alcohol drinking and after a period of imposed abstinence in free-choice drinking rhesus monkeys

1991 • 170 citations

Intravenous self-administration of drugs in rats.

1978 • 165 citations

Individual differences in amphetamine sensitization: Dose-dependent effects

1992 • 141 citations

Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol.

1989 • 134 citations

Emotional but not physical stress enhances intravenous cocaine self-administration in drug-naive rats

1993 • 133 citations

Children of substance abusers: A review of the literature

1986 • 121 citations

Life events-induced decrease of corticosteroid type I receptors is associated with reduced corticosterone feedback and enhanced vulnerability to amphetamine self-administration

1991 • 91 citations

Endorphins, opiates, and behavioural processes

1988 • 82 citations

Chronic neuroleptic treatment and mesolimbic dopamine denervation induce behavioural supersensitivity to opiates

1985 • 80 citations

Reward and Abuse of Opiates

1992 • 79 citations

Low doses of methylnaloxonium in the nucleus accumbens antagonize hyperactivity induced by heroin in the rat

1985 • 78 citations

Effects of naltrexone on intravenous cocaine self-administration in rats during food satiation and deprivation.

1986 • 77 citations

The dopamine hypothesis of opiate reward challenged

1987 • 77 citations

Relationships between Mesolimbic Dopamine Function and Eating Behaviora

1988 • 75 citations

Reinforcing stimulus properties of drugs

1979 • 70 citations

β-endorphin in brain limbic structures as neurochemical correlate of psychic dependence on drugs

1989 • 65 citations

Endogenous opiates and behavioral responses to environmental novelty

1978 • 59 citations

Opiate antagonists and rewarding brain stimulation

1988 • 59 citations

Intracerebroventricular naltrexone treatment attenuates acquisition of intravenous cocaine self-administration in rats

1991 • 56 citations

Perinatal methadone exposure and its influence on the behavioral ontogeny of rats

1978 • 54 citations

Effects of naloxone on heroin-, amphetamine- and caffeine-stimulated locomotor activity in the rat

1985 • 53 citations

Changes in morphine self-administration in rats induced by prostaglandin E1 and naloxone

1976 • 53 citations

Neurochemical predisposition to self-administer morphine in rats

1992 • 50 citations

Stimulant self-administration by animals: some comparisons with opiate self-administration.

1970 • 48 citations

Naloxone decreases ethanol consumption within a free choice paradigm in rats

1988 • 42 citations

The effect of prenatal exposure to methadone on neurotransmitters in neonatal rats

1990 • 36 citations

The Effects of Maternally-administered Morphine on Rat Foetal Development and Resultant Tolerance to the Analgesic Effect of Morphine

1972 • 35 citations

Chronic pretreatment with naltrexone facilitates acquisition of intravenous cocaine self-administration in rats

1990 • 33 citations

Interactions between naltrexone and non-opiate drugs evaluated by schedule-controlled behavior

1980 • 31 citations

Effects of prenatal morphine treatment of rats on mortality, bodyweight and analgesic response in the offspring

1989 • 29 citations

Opioids and development: a perspective on experimental models and methods.

1984 • 26 citations

Opiate self-administration in adult offspring of methadone-treated female rats

1985 • 23 citations

Effect of in utero administration of morphine on the subsequent development of self-administration behavior

1977 • 20 citations

Perinatal exposure to methadone: how do early biochemical alterations cause neurofunctional disturbances?

1988 • 16 citations

Changes in [3H]naloxone binding in spinal cord of rats treated prenatally with morphine

1983 • 14 citations

Increased amphetamine potency following chronic naltrexone administration in rats

1979 • 13 citations