Delineation of antigen contact residues on an MHC class II molecule.

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

1989 • 664 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

1987 • 297 citations

Murine Major Histocompatibility Complex Class-I Mutants: Molecular Analysis and Structure-Function Implications

1986 • 286 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

Three-Dimensional Structure of Antibodies

1988 • 256 citations

Immune Response(Ir)Genes of the Murine Major Histocompatibility Complex

1986 • 217 citations

Antigenic competition at the level of peptide-Ia binding.

1986 • 216 citations

Compartmentalization of MHC class II gene expression in transgenic mice

1988 • 201 citations

Implications of a Fab-like structure for the T-cell receptor

1989 • 193 citations

Peptide-dependent recognition of H–2Kb by alloreactive cytotoxic T lymphocytes

1989 • 168 citations

Evidence that multiple residues on both the α-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor

1988 • 151 citations

The T cell repertoire may be biased in favor of MHC recognition

1986 • 121 citations

An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself.

1990 • 110 citations

Structure of Class I Major Histocompatibility Antigens

1983 • 107 citations

Genetics and Expression of Mouse Ia Antigens

1985 • 99 citations

Specificity of the T cell receptor: two different determinants are generated by the same peptide and the I-Ak molecule.

1985 • 98 citations

Allorecognition of DR1 by T cells from a DR4/DRw13 responder mimics self-restricted recognition of endogenous peptides.

1989 • 87 citations

Direct evidence that a class II molecule and a simple globular protein generate multiple determinants.

1985 • 84 citations

The assignment of chain specificities for anti-Ia monoclonal antibodies using L cell transfectants.

1986 • 83 citations

Identical Vβ T-cell receptor genes used in alloreactive cytotoxic and antigen plus I–A specific helper T cells

1985 • 79 citations

Structural analysis of a peptide-HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor

1989 • 78 citations

Co-recognition of endogenous antigens with HLA-DR1 by alloreactive human T cell clones.

1989 • 76 citations

Structural requirements for the interaction between peptide antigens and I-Ed molecules.

1989 • 65 citations

Identical peptides recognized by MHC class I- and II-restricted T cells.

1989 • 63 citations

Comparison of the secondary structures of human class I and class II major histocompatibility complex antigens by Fourier transform infrared and circular dichroism spectroscopy.

1989 • 61 citations

Peptide-mediated modulation of T-cell allorecognition.

1988 • 59 citations

Predominant role of amino-terminal sequences in dictating efficiency of class II major histocompatibility complex alpha beta dimer expression.

1987 • 57 citations

T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas.

1989 • 48 citations

T cell recognition of bovine ribonuclease. Self/non-self discrimination at the level of binding to the I-Ak molecule.

1988 • 47 citations

A panel of unique HLA-A2 mutant molecules define epitopes recognized by HLA-A2-specific antibodies and cytotoxic T lymphocytes.

1989 • 45 citations

Alloreactivity studied with mutants of HLA-A2.

1989 • 43 citations

Characterization of cell lines expressing mutant I-Ab and I-Ak molecules allows the definition of distinct serologic epitopes on A alpha and A beta polypeptides.

1986 • 42 citations

A molecular basis for the Ia.2 and Ia.19 antigenic determinants.

1985 • 40 citations

Identification of an immunodominant region on the I-A beta chain using site-directed mutagenesis and DNA-mediated gene transfer.

1988 • 39 citations

Molecular characterization of the C3HfB/HeN H-2Kkm2 mutation. Implications for the molecular basis of alloreactivity.

1988 • 31 citations

Peptides recognized by class I restricted T cells also bind to MHC class II molecules

1990 • 31 citations

I-A alpha polymorphic residues that determine alloreactive T cell recognition.

1989 • 30 citations

Enhanced immunogenicity of a T cell immunogenic peptide by modifications of its N and C termini

1989 • 29 citations

Reconstruction of the immunogenic peptide RNase(43-56) by identification and transfer of the critical residues into an unrelated peptide backbone.

1989 • 29 citations

Functional sites on la molecules: A molecular dissection of Aα immunogenicity

1986 • 26 citations

Fine specificity of murine class II-restricted T cell clones for synthetic peptides of influenza virus hemagglutinin. Heterogeneity of antigen interaction with the T cell and the Ia molecule.

1988 • 24 citations

A beta polymorphic residues responsible for class II molecule recognition by alloreactive T cells.

1989 • 22 citations

Regulation of murine MHC class II molecule expression. Identification of A beta residues responsible for allele-specific cell surface expression.

1988 • 21 citations

Polymorphic residues on the I-A beta chain modulate the stimulation of T cell clones specific for the N-terminal peptide of the autoantigen myelin basic protein.

1989 • 18 citations

Epitopic analysis by anti-I-Ak monoclonal antibodies of I-Ak-restricted presentation of lysozyme peptides.

1989 • 16 citations

I-Ak polymorphisms define a functionally dominant region for the presentation of hen egg lysozyme peptides

1989 • 15 citations

Slot-machine mutagenesis of a polymorphic residue on the A kappa alpha-chain.

1988 • 9 citations

Functional sites on the A alpha-chain. Polymorphic residues involved in antigen presentation to insulin-specific, Ab alpha:Ak beta-restricted T cells.

1989 • 8 citations