Development and Characterization of Monoclonal Antibodies Specific to the Serotonin 5-HT_2AReceptor

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors

1985 • 1,855 citations

Antibodies to major histocompatibility antigens produced by hybrid cell lines

1977 • 1,727 citations

Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve

1979 • 1,034 citations

Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors

1994 • 861 citations

Neurotransmitters as growth regulatory signals: role of receptors and second messengers

1993 • 806 citations

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors

1985 • 803 citations

5-Hydroxytryptamine2 and 5-hydroxytryptamine1A receptors mediate opposing responses on membrane excitability in rat association cortex

1991 • 599 citations

A proposed new nomenclature for 5-HT receptors

1993 • 551 citations

Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro.

1987 • 550 citations

Comparative localization of serotonin_{1A, 1C}, and ₂ receptor subtype mRNAs in rat brain

1995 • 549 citations

Myelin: Biology and Chemistry

1992 • 436 citations

5-HT Receptor Classification and Nomenclature: Towards a Harmonization with the Human Genome

1997 • 413 citations

Ontogeny of the Serotonergic System in the Rat: Serotonin as a Developmental Signal^a

1990 • 403 citations

Immunocytochemical localization of serotonin1A receptors in the rat central nervous system

1996 • 370 citations

5-Hydroxytryptamine Receptor Subtypes

1988 • 361 citations

Stimulation of aortic smooth muscle cell mitogenesis by serotonin.

1986 • 327 citations

Serotonin 5-HT2A receptors are expressed on pyramidal cells and interneurons in the rat cortex

1997 • 324 citations

Immuno-localization of serotonin 5-HT6 receptor-like material in the rat central nervous system

1997 • 317 citations

The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.

1990 • 280 citations

The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain

1995 • 272 citations

Localization of the 5-hydroxytryptamine2C receptor protein in human and rat brain using specific antisera

1995 • 240 citations

Localization of the mRNA for the 5-HT2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites

1990 • 234 citations

Role of serotonin and other neurotransmitter receptors in brain development: basis for developmental pharmacology.

1991 • 230 citations

Immunocytochemical localization and description of neurons expressing serotonin2 receptors in the rat brain

1993 • 228 citations

Serotonin receptors: Subtypes, functional responses and therapeutic relevance

1995 • 224 citations

Biology of serotonergic transmission

1983 • 214 citations

5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells

1997 • 196 citations

Cloning and functional characterization of the rat stomach fundus serotonin receptor.

1992 • 192 citations

Biochemical and immunocytochemical characterization of antipeptide antibodies to a cloned GluR1 glutamate receptor subunit: Cellular and subcellular distribution in the rat forebrain

1993 • 190 citations

Molecular cloning, functional expression, and pharmacological characterization of a novel serotonin receptor (5-hydroxytryptamine2F) from rat stomach fundus.

1992 • 181 citations

Functional characteristics of heterologously expressed 5-HT receptors

1997 • 169 citations

Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypes

1991 • 168 citations

Identification and Localization of a Skeletal Muscle Secrotonin 5-HT2A Receptor Coupled to the Jak/STAT Pathway

1997 • 158 citations

Ultrastructural localization of 5-hydroxytryptamine1A receptors in the rat brain

1996 • 153 citations

Cloning and functional characterization of the human 5‐HT_2B serotonin receptor

1994 • 150 citations

Serotonin Modulation of Inferior Olivary Oscillations and Synchronicity: A Multiple‐electrode Study in the Rat Cerebellum

1995 • 148 citations

Immunohistochemical localisation of the serotonin 5‐HT2B receptor in mouse gut, cardiovascular system, and brain

1996 • 142 citations

Site-directed mutagenesis of the serotonin 5-hydroxytrypamine2 receptor: identification of amino acids necessary for ligand binding and receptor activation.

1993 • 138 citations

Ras Involvement in Signal Transduction by the Serotonin 5-HT2B Receptor

1996 • 132 citations

Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system

1996 • 114 citations

A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1α metabotropic glutamate receptors

1997 • 107 citations

Localization of 5-HT3 receptors in the rat spinal cord

1995 • 101 citations

Effect of the selective lesion of serotoninergic neurons on the regional distribution of 5-HT1A receptor mRNA in the rat brain

1992 • 100 citations

Production of specific anti-rat 5-HT1A receptor antibodies in rabbits injected with a synthetic peptide

1990 • 98 citations

5-Hydroxytryptamine2A (5-HT2A) receptor desensitization can occur without down-regulation.

1995 • 89 citations

Serotonin-glutamate interaction in rat cerebellum: involvement of 5-HT1 and 5-HT2 receptors

1988 • 77 citations

Neurons Expressing 5-HT2 Receptors in the Rat Brain: Neurochemical Identification of Cell Types by Immunocytochemistry

1994 • 68 citations

GluR1-immunopositive interneurons in rat neocortex

1996 • 61 citations

Assessment of binding indices and physiological responsiveness of the 5-HT2 receptor on human platelets

1987 • 60 citations

Direct immunocytochemical localization of 5‐hydroxytryptamine receptors in the adult rat spinal cord: A light and electron microscopic study using an anti‐idiotypic antiserum

1994 • 59 citations

Immunohistochemical mapping of cellular and subcellular distribution of 5-HT1A receptors in rat and human kidneys

1993 • 55 citations

Antipeptide antibodies against the 5-HT1A receptor

1992 • 51 citations

Immunolabeling of Central Serotonin 5‐HT_1Dβ Receptors in the Rat, Mouse, and Guinea Pig with a Specific Anti‐Peptide Antiserum

1995 • 51 citations

Serotonin Receptor Activation of Phosphoinositide Turnover in Uterine, Fundal, Vascular, and Tracheal Smooth Muscle

1987 • 46 citations

Production and characterization of polyclonal antibodies recognizing the intracytoplasmic third loop of the 5-hydroxytryptamine1A receptor

1994 • 39 citations

Neuronal localization of 5-HTIA receptor mRNA and protein in rat embryonic brain stem cultures

1994 • 37 citations

Evaluation of monoclonal antibodies to human plasma low density lipoproteins. A requirement for lipids to maintain antigenic structure

1982 • 37 citations

Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides

1995 • 36 citations

Production and characterization of a specific 5-HT2 receptor antibody

1993 • 34 citations

Immunological Characterization and Transmembrane Topology of 5‐Hydroxytryptamine₃ Receptors by Functional Epitope Tagging

1996 • 31 citations

Role of serotonin type 2 receptors in regulation of aldosterone production

1985 • 30 citations

Immunocytochemical localization of 5-HT1A receptors in the rat immature cerebellum

1993 • 25 citations

Identification of Serotonin Receptors Recognized by Anti‐Idiotypic Antibodies

1991 • 22 citations

Different Subcellular Localization of Muscarinic and Serotonin (S₂) Receptors in Human, Dog, and Rat Brain

1986 • 20 citations

5-Hydroxytryptamine2A receptors on cultured rat Schwann cells

1996 • 18 citations

Serotonin receptors expressed by myelinating Schwann cells in rat sciatic nerve

1997 • 15 citations

Characterization of Pharmacologically Active Anti‐Peptide Antibodies Directed Against the First and Second Extracellular Loops of the Serotonin 5‐HT_1A Receptor

1995 • 13 citations

Production of anti-peptide antibodies directed against the first and the second extracellular loop of the human serotonin 5-HT1A receptor

1994 • 6 citations

Production and characterization of an antibody directed against the mouse 5HT1B receptor

1995 • 6 citations

The Expression of Serotonin Receptors by Cultured Rat Schwann Cells Is a Function of Their Differentiation: Correlation with a Quiescent Myelinating Phenotype

1997 • 6 citations

Molecular Studies of 5‐HT Receptors^a

1990 • 5 citations

Characterisation of the human brain serotonin 5-HT1A receptor expressed in Chinese Hamster Ovary cells

1994 • 1 citations