HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei

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Applied Regression Analysis and Other Multivariable Methods

1989 • 8,685 citations

Analysis of Longitudinal Data

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Measurement of micronuclei in lymphocytes

1985 • 1,807 citations

The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations

1993 • 990 citations

The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes

1976 • 816 citations

The HUman MicroNucleus Project—An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans

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Applied Regression Analysis and Other Multivariable Methods

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Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. European Study Group on Cytogenetic Biomarkers and Health.

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Chromosomal aberrations in lymphocytes predict human cancer: a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH).

1998 • 487 citations

Analysis of Longitudinal Data.

1997 • 458 citations

Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment

1996 • 333 citations

Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults

1998 • 319 citations

A general model for the analysis of multilevel data

1988 • 241 citations

Important variables that influence base-line micronucleus frequency in cytokinesis-blocked lymphocytes—a biomarker for DNA damage in human populations

1998 • 199 citations

Age-related increase of baseline frequencies of sister chromatid exchanges, chromosome aberrations, and micronuclei in human lymphocytes.

1997 • 187 citations

The effect of donor age on spontaneous and induced micronuclei

1985 • 179 citations

Hepatogastroenterology

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Radiation induction of micronuclei in human lymphocytes

1988 • 167 citations

Folate, vitamin B12, homocysteine status and chromosome damage rate in lymphocytes of older men

1997 • 159 citations

Sister chromatid exchange and micronucleus frequency in human lymphocytes of 1,650 subjects in an Italian population: II. Contribution of sex, age, and lifestyle

1998 • 144 citations

Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesis-blocked lymphocytes

1994 • 134 citations

The relationship between micronuclei in human lymphocytes and plasma levels of vitamin C, Vitamin E, Vitamin B₁₂ and folic acid

1994 • 121 citations

Micronucleated lymphocytes in people occupationally exposed to potential environmental contaminants: the age effect

1991 • 112 citations

A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes

1992 • 107 citations

Cytogenetic analysis of a human population occupationally exposed to pesticides

1993 • 105 citations

Cytogenetic markers of susceptibility: influence of polymorphic carcinogen-metabolizing enzymes.

1997 • 100 citations

A Case Study Comparing a Meta-Analysis and a Pooled Analysis of Studies of Sinonasal Cancer among Wood Workers

1998 • 99 citations

Influence of sex on cytogenetic end points: evidence from a large human sample and review of the literature.

1995 • 93 citations

Micronuclei in Human Lymphocytes Irradiated in Vitro or in Vivo

1991 • 93 citations

Human lymphocytes micronucleus assay in Europe. An international survey

1997 • 89 citations

A cytogenetic study of radiological workers: effect of age, smoking and radiation burden on the micronucleus frequency

1996 • 88 citations

A more comprehensive application of the micronucleus technique for biomonitoring of genetic damage rates in human populations—experiences from the Chernobyl catastrophe

1997 • 82 citations

A Nordic data base on somatic chromosome damage in humans

1990 • 82 citations

Genetic effects of petroleum fuels: cytogenetic monitoring of gasoline station attendants

1995 • 75 citations

Cytogenetic effect of chronic low-dose, low-dose-rate γ-radiation in residents of irradiated buildings

1997 • 74 citations

Cytogenetic monitoring of occupational exposure to pesticides: Characterization ofGSTM1, GSTT1, andNAT2 genotypes

1996 • 70 citations

Influence of GSTM1 and GSTT1 polymorphisms on the frequency of chromosome aberrations in lymphocytes of smokers and pesticide-exposed greenhouse workers

1997 • 69 citations

A comparison of lymphocyte micronuclei and plasma micronutrients in vegetarians and non-vegetarians

1995 • 69 citations

Cytogenetic biomonitoring in traffic police workers: Micronucleus test in peripheral blood lymphocytes

1997 • 67 citations

Cytogenetic monitoring of fishermen with environmental mercury exposure

1994 • 67 citations

Simultaneous detection of X-chromosome loss and non-disjunction in cytokinesis-blocked human lymphocytes by in situ hybridization with a centromeric DNA probe; implications for the human lymphocyte in vitro micronucleus assay using cytochalasin B

1994 • 64 citations

Micronuclei-biological indicator for retrospective dosimetry after exposure to ionizing radiation

1998 • 64 citations

Vitamin-E supplements and their effect on vitamin-E status in blood and genetic damage rate in peripheral blood lymphocytes

1997 • 59 citations

Aging and Cellular Defense Mechanisms

1992 • 59 citations

Comparison between micronucleated lymphocyte rates observed in healthy subjects and cancer patients

1997 • 58 citations

Analysis of chromosome segregation by means of fluorescence in situ hybridization: application to cytokinesis-blocked human lymphocytes

1996 • 56 citations

Increased micronucleus formation in nurses with occupational nitrous oxide exposure in operating theaters

1996 • 52 citations

Sex chromosome loss and non-disjunction in women: Analysis of chromosomal segregation in binucleated lymphocytes

1996 • 51 citations

Lack of chromosomal aberration and micronucleus induction in human lymphocytes exposed to pulsed magnetic fields

1994 • 51 citations

The Cytokinesis-Block Micronucleus Technique

1996 • 50 citations

Indicators of genetic damage in alcoholics: reversibility after alcohol abstinence.

1999 • 49 citations

Radiosensitivity of Atomic Bomb Survivors as Determined with a Micronucleus Assay

1993 • 47 citations

50 Hz AC sinusoidal electric fields do not exert genotoxic effects (micronucleus formation) in human lymphocytes.

1993 • 44 citations

Micronuclei, a biomarker for chemoprevention trials: Results of a randomized study in oral pre‐malignancy

1994 • 42 citations

Micronuclei in lymphocytes of children from the vicinity of Chernobyl before and after 131I therapy for thyroid cancer

1996 • 40 citations

50 Hz AC Sinusoidal Electric Fields Do Not Exert Genotoxic Effects (Micronucleus Formation) in Human Lymphocytes

1993 • 38 citations

Age-related increase of mitomycin C-induced micronuclei in lymphocytes from Down's syndrome subjects

1990 • 36 citations

X-rays, microwaves and vinyl chloride monomer: their clastogenic and aneugenic activity, using the micronucleus assay on human lymphocytes

1992 • 35 citations

Frequency of micronuclei in lymphocytes from a group of floriculturists exposed to pesticides

1993 • 35 citations

Analysis of chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent damage resulting from low dose exposure to spindle poisons

1996 • 34 citations

Mutagenicity of vinyl chloride in man: comparison of chromosome aberrations with micronucleus and sister-chromatid exchange frequencies

1990 • 29 citations

Influence of serum micronutrients on the incidence of kinetochore-positive or -negative micronuclei in human peripheral blood lymphocytes

1998 • 26 citations

Sources of variability in the human lymphocyte micronucleus assay: A population‐based study

1995 • 26 citations

Radiation dose‐dependent variations of micronuclei production in cytochalasin B‐blocked human lymphocytes

1994 • 25 citations

Biomarker responses in human populations: towards a worldwide map

1999 • 24 citations

Biomonitoring of workers exposed to pesticides

1993 • 23 citations

Preservation of cytoplasm in the human lymphocyte micronucleus assay

1994 • 22 citations

Sister chromatid exchange and micronucleus frequency in human lymphocytes of 1,650 subjects in an Italian population: I. Contribution of methodological factors

1998 • 22 citations

Effect of blood storage on radiation-induced micronuclei in human lymphocytes

1999 • 20 citations

Interindividual variation in cytogenetic response to X-ray and colchicine measured with the cytokinesis-block micronucleus assay

1997 • 20 citations

The HUMN Project—An International Collaborative Study on the Use of the Micronucleus Technique for Measuring DNA Damage in Humans

2001 • 19 citations

A nine-year follow up study of a population occupationally exposed to vinyl chloride monomer

1996 • 18 citations

The sensitivity of the micronucleus assay for the detection of occupational exposure to vinyl chloride monomer

1994 • 16 citations

Heterogeneity of Chromosome Damage in β-thalassaemia Traits. An Evaluation of Spontaneous and γ-ray-induced Micronuclei and Chromosome Aberrations in Lymphocytesin Vitroafter G₀and G₂Phase Irradiation

1994 • 16 citations

In vitro micronucleus induction by polymethyl methacrylate bone cement in cultured human lymphocytes

1994 • 15 citations

Increased frequencies of sister chromatid exchanges and micronuclei in "in vitro" lymphocyte cultures treated with the fungicides thiram and ziram.

1997 • 12 citations

Monitoring human exposure to urban air pollutants

1993 • 12 citations

PERIPHERAL BLOOD -- Lymphocyte

1998 • 11 citations

Effects of Maillard reaction products on mutagen formation in boiled pork juice

1995 • 11 citations

Sources of variability in the determination of micronuclei in irradiated peripheral blood lymphocytes

1997 • 10 citations

Baseline Frequencies of Spontaneous Chromosome Aberrations, Sister Chromatid Exchanges and Micronuclei in Human Newborns.

1991 • 9 citations

Spontaneous and mitomycin-C-induced micronuclei in lymphocytes from subjects affected by Turner's syndrome

1996 • 9 citations

Assessment of two protocols for the human lymphocyte cytokinesis-blocked micronucleus assay

1995 • 8 citations

Reliability of finger stick capillary blood for the lymphocyte micronucleus assay

1997 • 6 citations

In vivo cytogenetic studies of the genotoxic effects of polymethyl methacrylate employed in orthopaedics.

1998 • 5 citations

Effects of dNTPs on the SCE frequency in plant root tip cells

1997 • 1 citations

P XIII.101 Late cytogenetic effects of chernobyl accident in humans

1997 • 1 citations

Influence of Age, Sex and Life Style Factors on the Spontaneous and Radiation Induced Micronuclei Frequencies

1996 • 1 citations