Augmented pulmonary IL-4 and IL-13 receptor subunit expression in idiopathic interstitial pneumonia

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias

2002 • 3,947 citations

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1999 • 1,715 citations

Idiopathic Pulmonary Fibrosis

1998 • 1,255 citations

Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1

2001 • 896 citations

Histopathologic Variability in Usual and Nonspecific Interstitial Pneumonias

2001 • 652 citations

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2–dominated inflammatory response

1999 • 601 citations

A Preliminary Study of Long-Term Treatment with Interferon Gamma-1b and Low-Dose Prednisolone in Patients with Idiopathic Pulmonary Fibrosis

1999 • 585 citations

Utility of a Lung Biopsy for the Diagnosis of Idiopathic Pulmonary Fibrosis

2001 • 553 citations

Idiopathic Nonspecific Interstitial Pneumonia: Prognostic Significance of Cellular and Fibrosing Patterns

2000 • 527 citations

Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4.

1992 • 498 citations

Thin-section CT obtained at 10-mm increments versus limited three-level thin-section CT for idiopathic pulmonary fibrosis: correlation with pathologic scoring.

1997 • 440 citations

Costimulation of Fibroblast Collagen and Transforming Growth Factor β1 Gene Expression by Monocyte Chemoattractant Protein-1 via Specific Receptors

1996 • 427 citations

A Histologic Pattern of Nonspecific Interstitial Pneumonia Is Associated with a Better Prognosis Than Usual Interstitial Pneumonia in Patients with Cryptogenic Fibrosing Alveolitis

1999 • 388 citations

Clinical significance of histological classification of idiopathic interstitial pneumonia

2002 • 371 citations

Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.

1998 • 353 citations

Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis.

1996 • 331 citations

The Relationship between Individual Histologic Features and Disease Progression in Idiopathic Pulmonary Fibrosis

2002 • 295 citations

The Contribution of Interleukin (IL)-4 and IL-13 to the Epithelial–Mesenchymal Trophic Unit in Asthma

2001 • 269 citations

Production of Interleukin 13 by Alveolar Macrophages from Normal and Fibrotic Lung

1998 • 266 citations

Idiopathic Pulmonary Fibrosis

2000 • 265 citations

Fibroblastic Foci in Usual Interstitial Pneumonia

2003 • 246 citations

Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts.

2000 • 217 citations

The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for interleukin-13–induced signal transduction through the STAT6 pathway

2001 • 216 citations

A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA)

1995 • 204 citations

IL-13-Induced Chemokine Responses in the Lung: Role of CCR2 in the Pathogenesis of IL-13-Induced Inflammation and Remodeling

2002 • 196 citations

IL-4 and IL-13 specifically increase adhesion molecule and inflammatory cytokine expression in human lung fibroblasts

1998 • 186 citations

Steroids in idiopathic pulmonary fibrosis: a prospective assessment of adverse reactions, response to therapy, and survival∗∗Access the “Journal Club” discussion of this paper at http://www.elsevier.com/locate/ajmselect/

2001 • 180 citations

Interleukin-13 Induces Dramatically Different Transcriptional Programs in Three Human Airway Cell Types

2001 • 169 citations

Idiopathic Pulmonary Fibrosis: Current Concepts

1998 • 166 citations

The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor.

1997 • 157 citations

Therapeutic Effect of IL-13 Immunoneutralization During Chronic Experimental Fungal Asthma

2001 • 151 citations

Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122.

1991 • 145 citations

Structure of and signal transduction through interleukin-4 and interleukin-13 receptors (review).

1998 • 139 citations

Differential Monocyte Chemoattractant Protein-1 and Chemokine Receptor 2 Expression by Murine Lung Fibroblasts Derived from Th1- and Th2-Type Pulmonary Granuloma Models

1999 • 138 citations

Structure of IL-13 Receptor: Analysis of Subunit Composition in Cancer and Immune Cells

1997 • 134 citations

Interstitial fibrosis and growth factors.

2000 • 129 citations

IL-4 Upregulates Tenascin Synthesis in Scleroderma and Healthy Skin Fibroblasts

1996 • 92 citations

Altered accessory cell function of alveolar macrophages: a possible mechanism for induction of Th2 secretory profile in idiopathic pulmonary fibrosis

1997 • 88 citations

Different cytokine profiles in cryptogenic fibrosing alveolitis and fibrosing alveolitis associated with systemic sclerosis A quantitative study of open lung biopsies

1999 • 87 citations

Receptor for Interleukin (IL) 13 Does Not Interact with IL4 but Receptor for IL4 Interacts with IL13 on Human Glioma Cells

1996 • 86 citations

Immunoreactive interleukin 4 and interferon-? expression by type II alveolar epithelial cells in interstitial lung disease

1999 • 80 citations

Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure

2002 • 60 citations

Classification of idiopathic interstitial pneumonias: making sense of the alphabet soup

2002 • 59 citations

IL-13 Fusion Cytotoxin Ameliorates Chronic Fungal-Induced Allergic Airway Disease in Mice

2001 • 58 citations

In vitroproduction of B cell growth factor and B cell differentiation factor by peripheral blood mononuclear cells and bronchoalveolar lavage T lymphocytes from patients with idiopathic pulmonary fibrosis

1990 • 48 citations

Cryptogenic fibrosing alveolitis/idiopathic pulmonary fibrosis

2001 • 45 citations

Increased interleukin-1 receptor antagonist in idiopathic pulmonary fibrosis. A compartmental analysis.

1995 • 39 citations

Respiratory Bronchiolitis Associated With Severe Dyspnea, Exertional Hypoxemia, and Clubbing

2000 • 39 citations

Interleukin-13 Fusion Cytotoxin Arrests Schistosoma mansoni Egg-Induced Pulmonary Granuloma Formation in Mice

2002 • 22 citations

In search of a cause of cryptogenic fibrosing alveolitis (CFA): one initiating factor or many?

1998 • 21 citations

Deleted Work

1955 • 0 citations

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