Cyclic AMP receptor protein functions as a repressor of the osmotically inducible promoter proP P1 in Escherichia coli

Experiments in molecular genetics

1972 • 28,260 citations

Escherichia coli and Salmonella :cellular and molecular biology

1996 • 8,124 citations

Improved single and multicopy lac-based cloning vectors for protein and operon fusions

1987 • 1,537 citations

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

1975 • 1,157 citations

Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°

1991 • 1,109 citations

TRANSCRIPTIONAL REGULATION BY cAMP AND ITS RECEPTOR PROTEIN

1993 • 819 citations

A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli

1988 • 719 citations

Cyclic AMP Receptor Protein: Role in Transcription Activation

1984 • 645 citations

A general method for rapid site-directed mutagenesis using the polymerase chain reaction

1990 • 642 citations

The cellular concentration of the sigma S subunit of RNA polymerase in Escherichia coli is controlled at the levels of transcription, translation, and protein stability.

1994 • 500 citations

Characterization of the cytoplasm of Escherichia coli K-12 as a function of external osmolarity

1991 • 478 citations

Transient accumulation of potassium glutamate and its replacement by trehalose during adaptation of growing cells of Escherichia coli K-12 to elevated sodium chloride concentrations

1988 • 389 citations

Dramatic changes in Fis levels upon nutrient upshift in Escherichia coli

1992 • 368 citations

Osmoregulation by potassium transport inEscherichia coli

1986 • 342 citations

Variability of the intracellular ionic environment of Escherichia coli. Differences between in vitro and in vivo effects of ion concentrations on protein-DNA interactions and gene expression.

1987 • 270 citations

Osmotic regulation of transcription: induction of the proU betaine transport gene is dependent on accumulation of intracellular potassium

1986 • 229 citations

Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: intracellular levels of sigma 70 and sigma 38

1995 • 219 citations

Origins of the osmoprotective properties of betaine and proline in Escherichia coli K-12

1992 • 218 citations

Interactions of the nucleoid-associated DNA-binding protein H-NS with the regulatory region of the osmotically controlled proU operon of Escherichia coli.

1994 • 213 citations

Identification of osmoresponsive genes in Escherichia coli: evidence for participation of potassium and proline transport systems in osmoregulation

1985 • 211 citations

The Escherichia coli nucleoid protein H-NS functions directly as a transcriptional repressor.

1993 • 196 citations

Binding protein dependent transport of glycine betaine and its osmotic regulation in Escherichia coli K12

1986 • 188 citations

The E.coli fis promoter is subject to stringent control and autoregulation.

1992 • 169 citations

Isolation and Sequencing of Escherichia coli Gene proP Reveals Unusual Structural Features of the Osmoregulatory Proline/Betaine transporter, ProP

1993 • 163 citations

Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation.

1993 • 146 citations

Proline transport and osmotic stress response in Escherichia coli K-12

1986 • 144 citations

[10] Footprinting protein-DNA complexes in Vivo

1991 • 129 citations

Proline porter II is activated by a hyperosmotic shift in both whole cells and membrane vesicles of Escherichia coli K12.

1988 • 126 citations

Complex transcriptional control of the sigma s-dependent stationary-phase-induced and osmotically regulated osmY (csi-5) gene suggests novel roles for Lrp, cyclic AMP (cAMP) receptor protein-cAMP complex, and integration host factor in the stationary-phase response of Escherichia coli

1993 • 122 citations

Osmotic regulation of L-proline transport in Salmonella typhimurium

1985 • 121 citations

Escherichia coli catabolite gene activator protein mutants defective in positive control of lac operon transcription

1991 • 103 citations

Fis activates the RpoS-dependent stationary-phase expression of proP in Escherichia coli

1995 • 85 citations

Osmotic control of proU transcription is mediated through direct action of potassium glutamate on the transcription complex.

1990 • 82 citations

Multiple mechanisms contribute to osmotic inducibility of proU operon expression in Escherichia coli: demonstration of two osmoresponsive promoters and of a negative regulatory element within the first structural gene

1991 • 81 citations

aldB, an RpoS-dependent gene in Escherichia coli encoding an aldehyde dehydrogenase that is repressed by Fis and activated by Crp

1995 • 75 citations

Two different Escherichia coli proP promoters respond to osmotic and growth phase signals

1995 • 73 citations

Osmoregulation of the maltose regulon in Escherichia coli

1986 • 66 citations

Rapid response to osmotic upshift by osmoregulated genes in Escherichia coli and Salmonella typhimurium

1988 • 63 citations

A transcriptional silencer downstream of the promoter in the osmotically controlled proU operon of Salmonella typhimurium.

1992 • 60 citations

Insertion proQ220::Tn5 alters regulation of proline porter II, a transporter of proline and glycine betaine in Escherichia coli

1989 • 60 citations

Compensating Effects of Opposing Changes in Putrescine (2+) and K+Concentrations onlacRepressor-lacOperator Binding:in VitroThermodynamic Analysis andin VivoRelevance

1996 • 57 citations

In an Escherichia coli coupled transcription-translation system, expression of the osmoregulated gene proU is stimulated at elevated potassium concentrations and by an extract from cells grown at high osmolality

1989 • 56 citations

proP-mediated proline transport also plays a role in Escherichia coli osmoregulation

1986 • 54 citations

Factors Reducing and Promoting the Effectiveness of Proline as an Osmoprotectant in Escherichia coli K12

1987 • 54 citations

Analysis of the promoters and transcripts involved in IS10 anti-sense RNA control

1988 • 53 citations

The Escherichia coli proU promoter element and its contribution to osmotically signaled transcription activation

1994 • 51 citations

Ion‐exchange reactions of proteins during DNA binding

1993 • 30 citations

Effects of anions on the binding of the cAMP receptor protein to the lactose promoter

1993 • 9 citations

Deleted Work

1955 • 0 citations