The Jak/Stat Pathway and Urokinase Receptor Signaling in Human Aortic Vascular Smooth Muscle Cells

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases

1991 • 848 citations

Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

1990 • 624 citations

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1991 • 578 citations

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes.

1990 • 480 citations

Migration of smooth muscle and endothelial cells. Critical events in restenosis.

1992 • 406 citations

Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness

1993 • 402 citations

Activation and Association of Stat3 with Src in v-Src-Transformed Cell Lines

1996 • 372 citations

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes.

1995 • 355 citations

The urokinase receptor is required for human monocyte chemotaxis in vitro.

1994 • 308 citations

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect.

1996 • 306 citations

Signal transduction through decay-accelerating factor. Interaction of glycosyl-phosphatidylinositol anchor and protein tyrosine kinases p56lck and p59fyn 1.

1992 • 286 citations

Upregulation of urokinase receptor expression on migrating endothelial cells

1993 • 277 citations

Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells.

1994 • 266 citations

Three-part inventions: intracellular signaling and induced proximity

1996 • 147 citations

JAK protein tyrosine kinases: their role in cytokine signalling

1994 • 125 citations

Differentiation of Vascular Smooth Muscle Cells and the Regulation of Protein Kinase C-α

1995 • 112 citations

Contrasting Effects of Plasminogen Activators, Urokinase Receptor, and LDL Receptor–Related Protein on Smooth Muscle Cell Migration and Invasion

1996 • 100 citations

Interaction of urokinase‐type plasminogenactivator (u‐PA) with its cellular receptor (u‐PAR) induces phosphorylation on tyrosine of a 38 kDa protein

1993 • 100 citations

JAKs and STATs branch out

1996 • 85 citations

Urokinase-Urokinase Receptor Interaction: Non-Mitogenic Signal Transduction in Human Epidermal Cells

1993 • 79 citations

Unique signal transduction of Eyk: constitutive stimulation of the JAK-STAT pathway by an oncogenic receptor-type tyrosine kinase.

1996 • 78 citations

High glucose concentrations and protein kinase C isoforms in vascular smooth muscle cells

1995 • 75 citations

Migrating Vascular Smooth Muscle Cells Polarize Cell Surface Urokinase Receptors after Injury in Vitro

1995 • 63 citations

Induction of c‐fos gene expression by urokinase‐type plasminogen activator in human ovarian cancer cells

1994 • 63 citations

Signal Transduction: Just another signalling pathway

1994 • 58 citations

Angiotensin II signalling events mediated by tyrosine phosphorylation

1996 • 56 citations

Jak1 kinase is required for cell migrations and anterior specification in zebrafish embryos

1997 • 52 citations

Extracellular proteolysis and the migrating vascular smooth muscle cell

1996 • 38 citations

PDGF Receptor-to-Nucleus Signaling of p91 (STAT1α) Transcription Factor in Rat Smooth Muscle Cells

1996 • 37 citations

Signal transduction via urokinase receptor: is a transmembrane adapter molecule really necessary?

1997 • 5 citations