Evaluating the role of CD4‐lymphocyte counts as surrogate endpoints in human immunodeficiency virus clinical trials

Regression Models and Life-Tables

1992 • 27,454 citations

Cox's Regression Model for Counting Processes: A Large Sample Study

1982 • 4,101 citations

The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

1987 • 3,000 citations

Surrogate endpoints in clinical trials: Definition and operational criteria

1989 • 1,929 citations

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

1985 • 1,830 citations

The Toxicity of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

1987 • 1,134 citations

Covariate measurement errors and parameter estimation in a failure time regression model

1982 • 629 citations

The Safety and Efficacy of Zidovudine (AZT) in the Treatment of Subjects with Mildly Symptomatic Human Immunodeficiency Virus Type 1 (HIV) Infection

1990 • 598 citations

Predictors of the Acquired Immunodeficiency Syndrome Developing in a Cohort of Seropositive Homosexual Men

1987 • 520 citations

Statistical analysis of the stages of HIV infection using a Markov model

1989 • 305 citations

The Natural History of Kaposi's Sarcoma in the Acquired Immunodeficiency Syndrome

1985 • 251 citations

Surrogate endpoints in clinical trials: Cardiovascular diseases

1989 • 235 citations

Effect of T4 count and cofactors on the incidence of AIDS in homosexual men infected with human immunodeficiency virus

1987 • 220 citations

HIV Infection: The Clinical Picture

1988 • 172 citations

Surrogate endpoints in clinical trials: Cancer

1989 • 154 citations

Evaluating Serial Cancer Marker Studies in Patients at Risk of Recurrent Disease

1981 • 102 citations

Discussion: “The Measurement of Oil-Film Thickness in Gear Teeth” (MacConochie, I. O., and Cameron, A., 1960, ASME J. Basic Eng., 82, pp. 29–34)

1960 • 47 citations

Surrogate endpoints in clinical trials: Ophthalmologic disorders

1989 • 47 citations