Calcitriol regulates the expression of the genes encoding the three key vitamin D₃ hydroxylases and the drug‐metabolizing enzyme CYP3A4 in the human fetal intestine

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism

1999 • 1,235 citations

Vitamin D Receptor As an Intestinal Bile Acid Sensor

2002 • 1,100 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Extrarenal Expression of 25-Hydroxyvitamin D₃-1α-Hydroxylase¹

2001 • 847 citations

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

1997 • 767 citations

Influence of the Vitamin D-binding Protein on the Serum Concentration of 1,25-Dihydroxyvitamin D3

1981 • 507 citations

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

1990 • 487 citations

Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis.

1991 • 479 citations

Regulation of cytochrome P450 (CYP) genes by nuclear receptors

2000 • 447 citations

Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method.

2000 • 399 citations

Cloning of Human 25-Hydroxyvitamin D-1α-Hydroxylase and Mutations Causing Vitamin D-Dependent Rickets Type 1

1997 • 398 citations

Elevated 1,25-dihydroxyvitamin D plasma levels in normal human pregnancy and lactation.

1979 • 322 citations

Transcriptional Control of Intestinal Cytochrome P-4503A by 1α,25-Dihydroxy Vitamin D₃

2001 • 321 citations

Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease.

1984 • 320 citations

Perinatal metabolism of vitamin D,,

2000 • 292 citations

Positive and Negative Regulations of the Renal 25-Hydroxyvitamin D3 1α-Hydroxylase Gene by Parathyroid Hormone, Calcitonin, and 1α,25(OH)2D3 in Intact Animals*

1999 • 291 citations

Extrarenal Expression of 25-Hydroxyvitamin D3-1 -Hydroxylase

2001 • 273 citations

Calcium, Vitamin D, and the Occurrence of Colorectal Cancer Among Women

1996 • 263 citations

Regulation of cytochrome P450 (CYP) genes by nuclear receptors

2000 • 260 citations

Inhibition of dietary fat-promoted colon carcinogenesis in rats by supplemental calcium or vitamin D₃

1988 • 215 citations

Human perinatal vitamin D metabolism I: 25-Hydroxyvitamin D in maternal and cord blood

1974 • 207 citations

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

2001 • 179 citations

Calcium and Vitamin D: Their Potential Roles in Colon and Breast Cancer Prevention

1999 • 156 citations

Isolation and expression of human 1,25-dihydroxyvitamin D3 24-hydroxylase cDNA.

1993 • 144 citations

Radioimmunoassay of the binding protein for vitamin D and its metabolites in human serum: concentrations in normal subjects and patients with disorders of mineral homeostasis.

1976 • 133 citations

Cloning of Human 25-Hydroxyvitamin D-1 -Hydroxylase and Mutations Causing Vitamin D-Dependent Rickets Type 1

1997 • 125 citations

Neonatal rickets in Asian immigrant population.

1973 • 113 citations

Biologic effects of epidermal growth factor in human fetal jejunum

1988 • 107 citations

Perinatal parathyroid hormone, vitamin D metabolites, and calcitonin in man

1980 • 103 citations

Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.

2001 • 100 citations

Expression of the gene encoding aromatase cytochrome P450 (CYP19) in fetal tissues.

1994 • 95 citations

Skeletal Changes during Pregnancy and Lactation: The Role of Vitamin D*

1980 • 89 citations

Placental transfer of vitamin D3 and 25-hydroxycholecalciferol in the rat.

1971 • 87 citations

Osteomalacia of the mother ?rickets of the newborn

1987 • 81 citations

Expression of the gene encoding aromatase cytochrome P450 (CYP19) in fetal tissues

1994 • 70 citations

Fetomaternal vitamin D relationships at term

1980 • 69 citations

Human Gastrointestinal Development

1990 • 68 citations

Expression of cytochrome P450b and P450e genes in small intestinal mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides.

1988 • 66 citations

25-Hydroxyvitamin D 1α-Hydroxylase: Structure of the Mouse Gene, Chromosomal Assignment, and Developmental Expression

2001 • 57 citations

Transfer of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 across the perfused human placenta

1984 • 56 citations

Concentrations of 24,25-dihydroxyvitamin D and 25-hydroxyvitamin D in paired maternal-cord sera

1978 • 49 citations

Expression of CYP27A, a gene encoding a vitamin D‐25 hydroxylase in human liver and kidney

2001 • 43 citations

Role of Fetal 1,25-Dihydroxyvitamin D Production in Intrauterine Phosphorus and Calcium Homeostasis

1985 • 42 citations

Expression of the 1,25-dihydroxyvitamin D3-24-hydroxylase gene in rat intestine: Response to calcium, vitamin D3 and calcitriol administration in vivo

1995 • 38 citations

Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6β‐hydroxylase

2001 • 33 citations

1,25-Dihydroxyvitamin D₃downregulates the rat intestinal vitamin D₃-25-hydroxylaseCYP27A

2001 • 31 citations

Effect of the Maternal Vitamin D Status at Parturition on the Vitamin D Status of the Neonatal Calf

1982 • 30 citations

Cell Proliferation in Developing Human Jejunum

1987 • 24 citations

Comparative in vivo expression of the calcitriol-24-hydroxylase gene in kidney and intestine

1997 • 23 citations

Effects of Calcitriol on Proliferation and Differentiation of Human Fetal Jejunum

1995 • 13 citations

Plasma vitamin D-binding protein and free 1,25-dihydroxyvitamin D3 index in pregnant ewes and their fetuses in the last month of gestation

1987 • 11 citations

Dietary calcium and phosphate restriction in guinea-pigs during pregnancy: fetal mineralization induces maternal hypocalcaemia despite increased 1 alpha,25-dihydroxycholecalciferol concentrations.

2000 • 11 citations

Metabolism rate of oxodipine in rats and humans: comparison of in vivo and in vitro data.

1992 • 10 citations

Renal reabsorption of inorganic phosphorus in pregnancy in relation to the calciotropic hormones

1998 • 10 citations

1,25(OH)2D and 24,25(OH)2D production in the developing kidney

1988 • 9 citations

Plasma Levels of Vitamin D Metabolites in Fetal and Pregnant Ewes

1987 • 9 citations

Dietary calcium and phosphate restriction in guinea-pigs during pregnancy: fetal mineralization induces maternal hypocalcaemia despite increased 1α,25-dihydroxycholecalciferol concentrations

2000 • 9 citations

Calcitriol Differentially Modulates mRNA Encoding Calcitriol Receptors and Calcium-Binding Protein 9 kDa in Human Fetal Jejunum

1996 • 8 citations

Contrôle génétique de la maturation du métabolisme des médicaments

2001 • 1 citations