Increased Levels of Nitrate and Surfactant Protein A Nitration in the Pulmonary Edema Fluid of Patients with Acute Lung Injury

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

1998 • 1,494 citations

Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.

1991 • 647 citations

Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

1994 • 599 citations

Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells.

1994 • 595 citations

Intact Epithelial Barrier Function Is Critical for the Resolution of Alveolar Edema in Humans

1990 • 588 citations

Factors Determining the Selectivity of Protein Tyrosine Nitration

1999 • 313 citations

Human monocytes/macrophages: NO or no NO?

1994 • 282 citations

Nitric Oxide and Nitrotyrosine in the Lungs of Patients with Acute Respiratory Distress Syndrome

2001 • 262 citations

Inactivation of .alpha.1-proteinase inhibitor by peroxynitrite

1992 • 253 citations

Deficiency of Alveolar Fluid Glutathione in Patients with Sepsis and the Adult Respiratory Distress Syndrome

1991 • 252 citations

3-Nitrotyrosine in the proteins of human plasma determined by an ELISA method

1998 • 244 citations

Oxidized Glutathione Is Increased in the Alveolar Fluid of Patients with the Adult Respiratory Distress Syndrome

1993 • 206 citations

Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: Evidence for neutrophil-mediated hydroxylation, nitration, and chlorination

1999 • 167 citations

Alveolar epithelial fluid transport and the resolution of clinically severe hydrostatic pulmonary edema

1999 • 159 citations

Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia

1985 • 157 citations

Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome

2000 • 151 citations

Nitric oxide inhibits Na⁺absorption across cultured alveolar type II monolayers

1998 • 129 citations

Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome.

1990 • 121 citations

Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat.

1998 • 118 citations

Autocatalytic oxidation of hemoglobin induced by nitrite: Activation and chemical inhibition

1985 • 81 citations

Urine Hydrogen Peroxide During Adult Respiratory Distress Syndrome in Patients With and Without Sepsis

1994 • 76 citations

Nitration of Proteins in Bronchoalveolar Lavage Fluid from Patients with Acute Respiratory Distress Syndrome Receiving Inhaled Nitric Oxide

1999 • 71 citations

Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages

2000 • 69 citations

[16] Measurement and significance of free and protein-bound 3-nitrotyrosine, 3-chlorotyrosine, and free 3-nitro-4-hydroxyphenylacetic acid in biologic samples: A high-performance liquid chromatography method using electrochemical detection

1999 • 65 citations

Inhibition of β-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock

1999 • 64 citations

Inhaled nitric oxide injures the pulmonary surfactant system of lambs in vivo

1996 • 62 citations

Nitration of Surfactant Protein A (SP-A) Tyrosine Residues Results in Decreased Mannose Binding Ability

1996 • 61 citations

The interplay of nitric oxide and peroxynitrite with signal transduction pathways: Implications for disease

1997 • 55 citations

Upregulation of alveolar liquid clearance after fluid resuscitation for hemorrhagic shock in rats

1997 • 52 citations

Nitrated SP-A does not enhance adherence ofPneumocystis cariniito alveolar macrophages

1998 • 45 citations

Ascorbate and glutathione homeostasis in vascular smooth muscle cells: cooperation with endothelial cells

1998 • 39 citations

Protein Nitration, Metabolites of Reactive Nitrogen Species, and Inflammation in Lung Allografts

2000 • 38 citations

Neutrophil-activating peptide-2 in patients with pulmonary edema from congestive heart failure or ARDS

1993 • 33 citations

DETANONOate, a Nitric Oxide Donor, Decreases Amiloride-sensitive Alveolar Fluid Clearance in Rabbits

2000 • 27 citations