Virulence of protein A-deficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Experiments in molecular genetics

1972 • 28,260 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Advanced bacterial genetics

1980 • 2,388 citations

The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage

1983 • 1,315 citations

SEGREGATION OF NEW LYSOGENIC TYPES DURING GROWTH OF A DOUBLY LYSOGENIC STRAIN DERIVED FROM ESCHERICHIA COLI K12

1954 • 979 citations

High frequency transformation of Bacillus subtilis protoplasts by plasmid DNA

1979 • 977 citations

Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus

1967 • 742 citations

Regulation of exoprotein gene expression in Staphylococcus aureus by agr

1986 • 618 citations

Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications.

1984 • 571 citations

Protein A of Staphylococcus aureus and related immunoglobulin receptors produced by streptococci and pneumonococci.

1982 • 561 citations

Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies

1982 • 498 citations

A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes

1980 • 379 citations

Staphylococcal protein A consists of five IgG-binding domains

1986 • 362 citations

Identification of clones that encode chicken tropomyosin by direct immunological screening of a cDNA expression library.

1983 • 307 citations

Practical statistics for experimental biologists

1986 • 282 citations

Isolation and Composition of Staphylococcal Alpha Toxin

1963 • 277 citations

Gene for staphylococcal protein A.

1983 • 224 citations

A genetic system for analysis of staphylococcal nuclease

1983 • 218 citations

Inactivation of the alpha-haemolysin gene of Staphylococcus aureus 8325-4 by site-directed mutagenesis and studies on the expression of its haemolysins

1986 • 171 citations

Region X, the cell‐wall‐attachment part of staphylococcal protein A

1984 • 161 citations

Virulence of Staphylococcus aureus in a mouse mastitis model: studies of alpha hemolysin, coagulase, and protein A as possible virulence determinants with protoplast fusion and gene cloning

1985 • 155 citations

Localization of Protein A in the Bacteria

1972 • 152 citations

Expression of a cloned Staphylococcus aureus alpha-hemolysin determinant in Bacillus subtilis and Staphylococcus aureus

1983 • 94 citations

MUTANTS OFSTAPHYLOCOCCUS AUREUSAFFECTED IN THE REGULATION OF EXOPROTEIN SYNTHESIS

1980 • 89 citations

Lysogenic Conversion of Staphylococci to Loss of -Toxin

1965 • 89 citations

Evidence for a coordinate transcriptional control of alpha-toxin and protein a synthesis inStaphylococcus aureus

1986 • 81 citations

Effect immunization with highly purified alpha- and beta-toxins on staphylococcal mastitis in rabbits

1977 • 79 citations

Expression of a Gene for Glucan-binding Protein from Streptococcus mutans in Escherichia coli

1985 • 78 citations

The use of synthetic oligonucleotides with universal templates for rapid DNA sequencing: results with staphylococcal replicon pC221.

1985 • 77 citations

Expression of the gene encoding protein A in Staphylococcus aureus and coagulase-negative staphylococci

1984 • 73 citations

Cloning and expression in Escherichia coli and Staphylococcus aureus of the beta-lysin determinant from Staphylococcus aureus: evidence that bacteriophage conversion of beta-lysin activity is caused by insertional inactivation of the beta-lysin determinant

1986 • 72 citations

Molecular cloning and expression of the epidermolytic toxin A gene of Staphylococcus aureus

1986 • 51 citations

Effects of staphylococcal products on locomotion and chemotaxis of human blood neutrophils and monocytes

1976 • 48 citations

Expression of a plasmid borne ethidium resistance determinant fromStaphylococcusinEscherichiacoli: Evidence for an efflux system

1985 • 44 citations

SUSCEPTIBILITY TO ANTIMICROBIAL AGENTS AND ANALYSIS OF PLASMIDS IN GENTAMICIN- AND METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS FROM DUBLIN HOSPITALS

1985 • 38 citations

Binding of Microbial Pathogens to Connective Tissue Fibronectin: An Early Step in Localized and Invasive Infections

1985 • 36 citations

A histopathological study of the effects of highly purified staphylococcal alpha and beta toxins on the lactating mammary gland and skin of the rabbit

1979 • 31 citations

A Study on the Biosynthesis of Protein A in Staphylococcus aureus

1974 • 29 citations

Chromosomal map location of the alpha-hemolysin structural gene in Staphylococcus aureus NCTC 8325

1986 • 18 citations

Effects of streptomycin and novobiocin on Staphylococcus aureus gene expression

1978 • 16 citations

Staphylococci and Staphylococcal Infections: Vols 1 and 2

1985 • 11 citations

A pplications of genetics to studies of bacterial virulence

1983 • 8 citations