Dendritic Anomalies in Disorders Associated with Mental Retardation

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

1999 • 4,776 citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1995 • 1,197 citations

Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

1997 • 1,019 citations

Histoanatomic observations of the brain in early infantile autism

1985 • 949 citations

Correlative Anatomy of the Nervous System

1962 • 821 citations

The Pathogenesis of Senile Plaques

1997 • 717 citations

Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth

1997 • 578 citations

Neuropathology of Infantile Autism

1998 • 574 citations

Dendritic Spine "Dysgenesis" and Mental Retardation

1974 • 520 citations

Analysis of neocortex in three males with the fragile X syndrome

1991 • 506 citations

Rett Syndrome and Beyond: Recurrent Spontaneous and Familial MECP2 Mutations at CpG Hotspots

1999 • 502 citations

Broad Thumbs and Toes and Facial Abnormalities

1963 • 501 citations

Dendritic injury is a pathological substrate for human immunodeficiency virus—related cognitive disorders

1997 • 470 citations

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1996 • 445 citations

Disorders of Neuronal Migration

1987 • 444 citations

Hippocampus in autism: a Golgi analysis

1995 • 373 citations

Bridging cognition, the brain and molecular genetics: evidence from Williams syndrome

1999 • 366 citations

Selective Dendritic Alterations in the Cortex of Rett Syndrome

1995 • 354 citations

Adult fragile X syndrome

1985 • 353 citations

Presence of soluble amyloid β–peptide precedes amyloid plaque formation in Down's syndrome

1996 • 328 citations

Autism and Mental Retardation

1980 • 315 citations

Abnormal neuronal development in the visual cortex of the human fetus and infant with down's syndrome. A quantitative and qualitative golgi study

1981 • 300 citations

Cerebral Morphologic Distinctions Between Williams and Down Syndromes

1993 • 296 citations

Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis

2005 • 295 citations

Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study

1972 • 286 citations

Pyramidal cell abnormalities in the motor cortex of a child with Down's syndrome. A Golgi study

1976 • 283 citations

Distortion of neuronal geometry and formation of aberrant synapses in neuronal storage disease

1976 • 278 citations

Dendritic atrophy in children with Down's syndrome

1986 • 275 citations

THE DENSITY OF SYNAPSES AND NEURONS IN NORMAL, MENTALLY DEFECTIVE AND AGEING HUMAN BRAINS

1975 • 223 citations

Dendritic development in neocortex of children with mental defect and infantile spasms

1974 • 216 citations

Rett syndrome

1994 • 215 citations

Growth and development of the brain in Down syndrome.

1991 • 209 citations

Development of the Superior Temporal Neocortex Is Anomalous in Trisomy 21

1994 • 208 citations

Towards the neural basis for hypersociability in a genetic syndrome

1999 • 208 citations

Pathology of Mental Retardation

1973 • 200 citations

Neuropathology of Rett syndrome

1988 • 199 citations

Down's dyndrome and Alzheimer's disease: dendritic spine counts in the hippocampus

1990 • 194 citations

Neuroanatomy of Rett syndrome: A volumetric imaging study

1993 • 190 citations

Dendritic differentiation in human cerebral cortex: normal and aberrant developmental patterns.

1975 • 186 citations

Spine distribution along the apical dendrites of the pyramidal neurons in Down's syndrome

1980 • 185 citations

Isolation of an FMRP-Associated Messenger Ribonucleoprotein Particle and Identification of Nucleolin and the Fragile X-Related Proteins as Components of the Complex

1999 • 179 citations

Cognitive impairment in neurofibromatosis type 1

1999 • 174 citations

Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome

1995 • 172 citations

The pattern of dendritic development in the cerebral cortex of the rat

1988 • 147 citations

Morphologic and histoanatomic observations of the brain in untreated human phenylketonuria

1982 • 145 citations

[The tropical localization and content of noradrenalin and dopamine (3-hydroxytyramine) in the substantia nigra of normal persons and patients with Parkinson's disease].

1963 • 143 citations

Structural correlates of information storage in the mammalian brain: a review and hypothesis

1984 • 139 citations

A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3"-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression

1999 • 134 citations

Decreased Dendritic Branching in Frontal, Motor and Limbic Cortex in Rett Syndrome Compared with Trisomy 21

1998 • 133 citations

Rett syndrome: A disorder affecting early brain growth

1997 • 132 citations

The Golgi Rapid Method in Clinical Neuropathology: The Morphologic Consequences of Suboptimal Fixation

1978 • 131 citations

Normal and Aberrant Neuronal Development in the Cerebral Cortex of Human Fetus and Young Infant

1975 • 130 citations

Dendrites, dementia and the down syndrome

1989 • 129 citations

Dendritic and histochemical development and ageing in patients with Down's syndrome

1994 • 123 citations

Cerebrocortical microdysgenesis in neurologically normal subjects

1989 • 115 citations

Neuropathology of rett syndrome

1986 • 114 citations

Structural organization of the cerebral cortex (motor area) in human chromosomal aberrations. A golgi study. I. D1 (13–15) trisomy, patau syndrome

1974 • 112 citations

A Perspective: The Role of Disordered Genetic Control of Neurogenesis in the Pathogenesis of Migration Disorders

1994 • 104 citations

Effects of nutrition on brain development in humans

1993 • 100 citations

Cytoarchitectonic anomalies in a genetically based disorder

1994 • 99 citations

Rubinstein-Taybi syndrome: A natural history study

2005 • 94 citations

Dendritic Spine Pathology in Infants With Severe Protein-Calorie Malnutrition

1999 • 94 citations

Molecular and cellular genetics of fragile X syndrome

1999 • 86 citations

Dendritic and synaptic pathology in mental retardation

1991 • 84 citations

Synaptic development in the human fetus: A morphometric analysis of normal and Down's syndrome neocortex

1984 • 79 citations

Association of Chiari I malformation and Williams syndrome

1995 • 79 citations

Golgi-Cox and Rapid Golgi Methods as Applied to Autopsied Human Brain Tissue

1982 • 78 citations

Abnormal Expression of Microtubule-Associated Protein 2 (MAP-2) in Neocortex in Rett Syndrome

1995 • 76 citations

Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome

1997 • 75 citations

Fine structure of cortical tubers in tuberous sclerosis: A Golgi study

1984 • 74 citations

THE EFFECT OF EARLY INTERVENTION AND PRE‐SCHOOL STIMULUS ON THE DEVELOPMENT OF THE DOWN'S SYNDROME CHILD

1979 • 73 citations

The Cellular Pathology of Neuronal Ceroid-Lipofuscinosis

1977 • 72 citations

Amelioration of fetal alcohol-related neurodevelopmental disorders in rats

2000 • 69 citations

Effects of prenatal malnutrition and postnatal nutritional rehabilitation on CA3 hippocampal pyramidal cells in rats of four ages

1994 • 67 citations

Effects of protein deprivation on pyramidal cells of the visual cortex in rats of three age groups

1990 • 66 citations

Ectopic dendritic growth in mature pyramidal neurones in human ganglioside storage disease

1978 • 66 citations

Consequences of Trisomy 16 for Mouse Brain Development: Corticogenesis in a Model of Down Syndrome

1996 • 66 citations

Cognitive deficits in normally intelligent patients with tuberous sclerosis

1999 • 64 citations

Microtubule disarray in cortical dendrites and neurobehavioral failure. I. Golgi and electron microscopic studies

1982 • 62 citations

No evidence for disruption of normal patterns of mRNA localization in dendrites or dendritic transport of recently synthesized mRNA in FMR1 knockout mice, a model for human fragile-X mental retardation syndrome

1998 • 59 citations

Newborn Basal Forebrain Lesions Disrupt Cortical Cytodifferentiation as Visualized by Rapid Golgi Staining

1991 • 57 citations

Cellular and molecular basis of cerebral dysgenesis

1997 • 53 citations

Longitudinal changes in cognitive and adaptive behavior in fragile X females: a prospective multicenter analysis.

1999 • 53 citations

Dendritic and Synaptic Development in Human Cerebral Cortex: Time Course and Critical Periods

1999 • 52 citations

Dendritic development in neocortex of infants with early postnatal life undernutrition

1993 • 51 citations

Abnormalities in neuronal maturation in Rett syndrome neocortex: preliminary molecular correlates.

1997 • 48 citations

Learning and memory in theFMR1 knockout mouse

1999 • 46 citations

Abnormal dendritic patterns and aberrant spine development in Bourneville's disease--a Golgi survey.

1984 • 42 citations

Neuropathologic findings in patients of a hospital for the mentally deficient. A survey of 359 cases.

1967 • 40 citations

Dendritic development and mental defect.

1970 • 38 citations

Nuclear calcium-activated gene expression: possible roles in neuronal plasticity and epileptogenesis

1999 • 32 citations

Expression Analysis and Protein Localization of the Human HPC-1/Syntaxin 1A, a Gene Deleted in Williams Syndrome

1999 • 31 citations

A Golgi study of the brain malformation in Zellweger's cerebro-hepato-renal disease

1981 • 31 citations

Rett Syndrome Studies of Natural History and Search for a Genetic Marker

1995 • 31 citations

Transgenic Mouse Models of Alzheimer's Disease and Amyotrophic Lateral Sclerosis

1998 • 30 citations

Origin and Roles of Nuclear Matrix Proteins. Specific Functions of the MAR-Binding Protein MeCP2/ARBP

1999 • 29 citations

The effect of hyperphenylalaninemia on size and density of synapses in rat neocortex

1979 • 29 citations

The growth of non-pyramidal neurons in the primary motor cortex of man: a Golgi study.

1997 • 27 citations

Tuberous sclerosis: a Golgi study of cortical tuber.

1984 • 27 citations

Rubinstein-Taybi syndrome: Cranial MR imaging findings

1995 • 25 citations

Thyroid hormone effects on neuronal differentiation during brain development.

1992 • 24 citations

A role for gene therapy in mental retardation

1995 • 22 citations

[Neurohistological findings in the parietal cortex of children with chromosome aberrations].

1992 • 21 citations

Prefrontal neocortical disturbances in mental retardation

1993 • 18 citations

Dendritic structure alterations induced by hypothyroidism in pyramidal neurons of the rat visual cortex

1986 • 18 citations

Microtubular disarray in cortical dendrites and neurobehavioral failure. II. Computer reconstruction of perturbed microtubular arrays

1982 • 17 citations

The Neuropathology of Williams Syndrome

1995 • 16 citations

Golgi and computer morphometric analysis of cortical dendrites in metabolic storage disease

1985 • 13 citations

Normalization of dendritic spine numbers in rat hippocampus after termination of phenylacetate injections (PKU model)

1985 • 13 citations

QUANTITATIVE DETERMINATION OF SYNAPTIC DENSITY AND THEIR MORPHOLOGY DURING THE POSTNATAL BRAIN DEVELOPMENT IN VISUAL CORTEX OF DOWN SYNDROME BRAIN

1985 • 13 citations

Rapid response genes as markers of cellular signaling during cortical histogenesis: Their potential in understanding mental retardation

1994 • 12 citations

Influence of Iodine Deficiency on Human Fetal Thyroid Gland and Brain

1989 • 12 citations

Neural activity and immediate early gene expression in the cerebral cortex

1999 • 11 citations

Paroxysmal Supraventricular Tachycardia in Infancy

1963 • 10 citations

Neuropathological findings in the rubinstein-taybi syndrome.

1973 • 9 citations

The neuroanatomy of Rett syndrome: Neuropathological and neuroimaging studies

1998 • 6 citations

[Quantitative study of the dendritic spins of lamina V pyramidal neurons of the frontal lobe in children with severe mental retardation].

1990 • 5 citations

The Effect of Early Experiences on the Development of Cortical Plasticity

1999 • 3 citations

Cytoskeletal Determinants of Dendritic Development and Function: Implications for Mental Retardation

1999 • 3 citations

Deleted Work

1955 • 0 citations