Airway Inflammation Is Present during Clinical Remission of Atopic Asthma

Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness

1991 • 681 citations

Endogenous Airway Acidification

2000 • 644 citations

Airway Mucosal Inflammation Even in Patients with Newly Diagnosed Asthma

1993 • 543 citations

Dissociation between Airway Inflammation and Airway Hyperresponsiveness in Allergic Asthma

1998 • 525 citations

Nitric oxide and asthmatic inflammation

1995 • 514 citations

Quantitation of Mast Cells and Eosinophils in the Bronchial Mucosa of Symptomatic Atopic Asthmatics and Healthy Control Subjects Using Immunohistochemistry

1990 • 463 citations

Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid

1998 • 441 citations

The human mast cell☆☆☆★

1997 • 351 citations

Tenascin Is Increased in Airway Basement Membrane of Asthmatics and Decreased by an Inhaled Steroid

1997 • 347 citations

Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics

1993 • 336 citations

Airway Inflammation in Mild Intermittent and in Persistent Asthma

1998 • 322 citations

Combined Use of Exhaled Hydrogen Peroxide and Nitric Oxide in Monitoring Asthma

1998 • 253 citations

The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway

1997 • 246 citations

Inhaled corticosteroids decrease subepithelial collagen deposition by modulation of the balance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 expression in asthma☆☆☆

1999 • 217 citations

Airway inflammation and remodeling in asthma

2000 • 197 citations

Adolescents in Clinical Remission of Atopic Asthma Have Elevated Exhaled Nitric Oxide Levels and Bronchial Hyperresponsiveness

2000 • 196 citations

Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness.

1993 • 190 citations

Adult patients may outgrow their asthma: a 25-year follow-up study.

1997 • 178 citations

Exhaled nitric oxide and sputum eosinophil markers of inflammation in asthmatic children

1999 • 165 citations

Bronchial responsiveness to distilled water and methacholine and its relationship to inflammation and remodeling of the airways in asthma.

1996 • 150 citations

Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma

2000 • 142 citations

Airway remodeling in asthma amplifies heterogeneities in smooth muscle shortening causing hyperresponsiveness

1999 • 130 citations

T Cells and Chronic Asthma

1999 • 127 citations

Variation in the measurements of basement membrane thickness and inflammatory cell number in bronchial biopsies

1998 • 117 citations

Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma?

1997 • 104 citations

Application of monoclonal antibodies against major basic protein (BMK‐13) and eosinophil cationic protein (EG1 and EG2) for quantifying eosinophils in bronchial biopsies from atopic asthma

1992 • 95 citations

Bronchial biopsy findings in intermittent or "early" asthma☆☆☆

1996 • 88 citations

Airway Basophil and Mast Cell Density in Patients with Bronchial Asthma: Relationship to Bronchial Hyperresponsiveness

1996 • 81 citations

The natural history of asthma

1998 • 77 citations

Asthma: A disease of inflammation and repair

2000 • 70 citations

Experimental and theoretical study of strain-induced AlGaAs/GaAs quantum dots using a self-organized GaSb island as a stressor

1999 • 66 citations

Increased expression of tissue inhibitor of metalloproteinase-1 and loss of correlation with matrix metalloproteinase-9 by macrophages in asthma.

1999 • 63 citations

Inflammatory and T-cell profile of asthmatic airways 6 hours after local allergen provocation.

1996 • 47 citations

Structural consequences of airway inflammation in asthma

2000 • 43 citations

Does the Mast Cell Still Have a Key Role in Asthma?*

1997 • 39 citations

Cellular and mediator responses twenty-four hours after local endobronchial allergen challenge of asthmatic airways

1996 • 33 citations

Lung function in asthmatic children after year or more without symptoms or treatment.

1978 • 28 citations

Peripheral blood markers: evaluation of inflammation in asthma.

1998 • 26 citations

Atopy, lung function and bronchial responsiveness in symptom-free paediatric asthma patients

1997 • 26 citations

Eosinophils in the bronchial mucosa in relation to methacholine dose-response curves in atopic asthma

1999 • 24 citations

Structural alterations and inflammation of bronchi in asthma.

1998 • 23 citations

The immunopharmacology of mild asthma☆☆☆★

1996 • 21 citations

Objective indicators of severity of asthma

1994 • 19 citations

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