Identification of human papillomavirus type 18 transforming genes in immortalized and primary cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.

1983 • 2,011 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

1985 • 1,481 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

1984 • 1,308 citations

Zinc fingers: Gilt by association

1988 • 799 citations

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

1987 • 760 citations

Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein.

1986 • 665 citations

The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A

1988 • 657 citations

The Physical State of Human Papillomavirus Type 16 DNA in Benign and Malignant Genital Tumours

1985 • 480 citations

The Approaching Era of the Tumor Suppressor Genes

1987 • 468 citations

Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes.

1986 • 440 citations

Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.

1987 • 351 citations

Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome

1987 • 341 citations

Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implications for cervical carcinogenesis.

1987 • 327 citations

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region.

1987 • 294 citations

Bovine papillomavirus contains multiple transforming genes.

1985 • 283 citations

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator

1987 • 278 citations

Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 18) in cervical carcinoma cells.

1987 • 272 citations

Human papillomavirus type 16 DNA-induced malignant transformation of NIH 3T3 cells

1986 • 235 citations

Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.

1987 • 230 citations

Human Papillomavirus in Clinically and Histologically Normal Tissue of Patients with Genital Cancer

1986 • 225 citations

The major human papillomavirus protein in cervical cancers is a cytoplasmic phosphoprotein

1987 • 203 citations

Identification of a second transforming region in bovine papillomavirus DNA.

1984 • 197 citations

Human papillomavirus types 6 and 11 mRNAs from genital condylomata acuminata

1987 • 197 citations

The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells

1987 • 180 citations

Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product

1987 • 173 citations

Human papillomaviruses and cancer

1986 • 154 citations

Human papillomavirus type 16 open reading frame E7 encodes a transforming gene for rat 3Y1 cells

1988 • 143 citations

Identification of Human Papillomavirus Type 18 E6 Polypeptide in Cells Derived from Human Cervical Carcinomas

1987 • 141 citations

Identification of the Protein Encoded by the E6 Transforming Gene of Bovine Papillomavirus

1985 • 136 citations

Upstream promoter element of the human metallothionein-IIA gene can act like an enhancer element.

1985 • 122 citations

Transforming activity of human papillomavirus type 16 DNA sequence in a cervical cancer.

1986 • 121 citations

Immortalization of primary rat cells by human papillomavirus type 16 subgenomic DNA fragments controlled by the SV40 promoter

1988 • 112 citations

Genital papillomavirus infections.

1985 • 110 citations

Enhancers and trans-acting E2 transcriptional factors of papillomaviruses

1987 • 102 citations

Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18

1988 • 94 citations

Regulation of human papillomavirus type 11 enhancer and E6 promoter by activating and repressing proteins from the E2 open reading frame: functional and biochemical studies

1988 • 93 citations

Functional mapping of the human papillomavirus type 11 transcriptional enhancer and its interaction with the trans-acting E2 proteins.

1988 • 93 citations

Intracellular localization and DNA-binding properties of human papillomavirus type 18 E6 protein expressed with a baculovirus vector

1989 • 63 citations

Study of the E2 gene product of the cottontail rabbit papillomavirus reveals a common mechanism of transactivation among papillomaviruses

1988 • 36 citations