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APIC guideline for selection and use of disinfectants

Data up to Jan 2025

Published1990
Citations569
References238

Total Citations Per Year

Abstract

References (238)

Manual of Clinical Microbiology.

1980 • 14,937 citations

Manual of Clinical Microbiology

1970 • 2,775 citations

Cecil Textbook of Medicine.

1985 • 2,154 citations

Disinfection, sterilization, and preservation

1983 • 1,751 citations

Nosocomial Acquisition ofClostridium difficileInfection

1989 • 1,367 citations

Disinfection, sterilization, and preservation

1991 • 972 citations

Effects of ozone, chlorine dioxide, chlorine, and monochloramine on Cryptosporidium parvum oocyst viability

1990 • 762 citations

Disinfection, Sterilization and Preservation

1969 • 721 citations

Prevention and Control of Nosocomial Infections.

1987 • 717 citations

The association for the advancement of medical instrumentation

1974 • 484 citations

Chemical disinfection of medical and surgical materials

1968 • 460 citations

Principles and practice of disinfection, preservation, and sterilization

1992 • 457 citations

CDC Guideline for Handwashing and Hospital Environmental Control, 1985

1986 • 394 citations

Stability and Inactivation of HTLV-III/LAV Under Clinical and Laboratory Environments

1986 • 380 citations

Disinfection and Inactivation of the Human T Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus

1985 • 371 citations

Increased bactericidal activity of dilute preparations of povidone-iodine solutions

1982 • 361 citations

Bacterial spores and chemical sporicidal agents

1990 • 352 citations

Infection control recommendations for the dental office and the dental laboratory

1988 • 318 citations

Unrecognized Human Immunodeficiency Virus Infection in Emergency Department Patients

1988 • 291 citations

Guideline for isolation precautions in hospitals

1984 • 285 citations

Guideline for use of topical antimicrobial agents

1988 • 253 citations

Disinfection and Sterilization

1965 • 252 citations

ACQUISITION OF CLOSTRIDIUM DIFFICILE FROM THE HOSPITAL ENVIRONMENT1

1988 • 248 citations

INACTIVATION OF LYMPHADENOPATHY ASSOCIATED VIRUS BY CHEMICAL DISINFECTANTS

1984 • 243 citations

URINARY INFECTION IN THE TWO SEXES

1966 • 235 citations

Efficacies of selected disinfectants against Mycobacterium tuberculosis

1990 • 212 citations

Physical and Biochemical Characterization of the qacA Gene Encoding Antiseptic and Disinfectant Resistance in Staphylococcus aureus

1989 • 203 citations

Guidelines for Prevention of Transmission of Human Immunodeficiency Virus and Hepatitis B Virus to Health-Care and Public-Safety Workers

1989 • 194 citations

Mycobacterium chelonaeCausing Otitis Media in an Ear-Nose-and-Throat Practice

1988 • 189 citations

Inactivation of hepatitis B virus by intermediate-to-high-level disinfectant chemicals

1983 • 189 citations

Institutional outbreaks of rotavirus diarrhoea: potential role of fomites and environmental surfaces as vehicles for virus transmission

1986 • 175 citations

Cleaning and disinfection of equipment for gastrointestinal flexible endoscopy: interim recommendations of a Working Party of the British Society of Gastroenterology.

1988 • 170 citations

Pseudobacteremia Attributed to Contamination of Povidone-Iodine with Pseudomonas cepacia

1981 • 168 citations

Scrapie infectious agent is virus-like in size and susceptibility to inactivation

1984 • 161 citations

Guideline for handwashing and hospital environmental control, 1985 supersedes guideline for hospital environmental control published in 1981

1986 • 160 citations

Newer Data on the Inactivation of Scrapie Virus or Creutzfeldt-Jakob Disease Virus in Brain Tissue

1986 • 159 citations

Chemical disinfection of hepatitis A virus on environmental surfaces

1990 • 157 citations

Depigmentation Caused by Phenolic Detergent Germicides

1970 • 156 citations

Efficacy of a variety of disinfectants against Listeria spp

1990 • 150 citations

Buffered Glutaraldehyde–A New Chemical Sterilizing Solution

1963 • 149 citations

Pseudobacteremia Caused by Povidone-Iodine Solution Contaminated withPseudomonas cepacia

1981 • 147 citations

Unsuspected Human Immunodeficiency Virus in Critically III Emergency Patients

1987 • 146 citations

Chemical Disinfection of Creutzfeldt–Jakob Disease Virus

1982 • 144 citations

Nosocomial infections from contaminated endoscopes: A flawed automated endoscope washer. An investigation using molecular epidemiology

1991 • 142 citations

A simple and effective method for inactivating virus infectivity in formalin‐fixed tissue samples from patients with Creutzfeldt‐Jakob disease

1990 • 140 citations

Disinfection studies with two strains of mouse-passaged scrapie agent

1983 • 133 citations

Cloning and expression of Staphylococcus aureus plasmid-mediated quaternary ammonium resistance in Escherichia coli

1985 • 132 citations

Bronchopulmonary Cross-Colonization and Infection Related to Mycobacterial Contamination of Suction Valves of Bronchoscopes

1989 • 128 citations

Disinfectants, their use and evaluation of effectiveness.

1981 • 128 citations

Anticipatics, handwashing, and handwashing facililties

1983 • 128 citations

Esophagoscopy as a Source of Pseudomonas Aeruginosa Sepsis in Patients with Acute Leukemia: the Need for Sterilization of Endoscopes

1974 • 126 citations

Biocidal Activities of Glutaraldehyde and Related Compounds

1967 • 126 citations

Catheter-associated bacteriuria. Failure to reduce attack rates using periodic instillations of a disinfectant into urinary drainage systems.

1984 • 120 citations

Water-Related Nosocomial Pneumonia Caused by Legionella pneumophila Serogroups 1 and 10

1985 • 118 citations

Susceptibility of hepatitis B virus to disinfectants or heat

1984 • 117 citations

Survival and Disinfectant Inactivation of the Human Immunodeficiency Virus: A Critical Review

1991 • 115 citations

Chemical colitis due to endoscope cleaning solutions: A mimic of pseudomembranous colitis

1988 • 114 citations

THE RELATIONSHIP OF CONCENTRATION AND GERMICIDAL EFFICIENCY OF ETHYL ALCOHOL

1950 • 114 citations

Decreased Incidence of Bacteriuria Associated with Periodic Instillations of Hydrogen Peroxide into the Urethral Catheter Drainage Bag

1980 • 113 citations

Precautions in handling tissues, fluids, and other contaminated materials from patients with documented or suspected Creutzfeldt-Jakob disease

1986 • 113 citations

Legionnaires' Disease Associated with a Hospital Water System: A Cluster of 24 Nosocomial Cases

1983 • 112 citations

Occupational dermatoses in hospital cleaning women

1983 • 111 citations

Elimination of high titre HIV from fibreoptic endoscopes.

1990 • 111 citations

Chemical inactivation of HIV on surfaces.

1989 • 111 citations

Two per cent glutaraldehyde

1982 • 110 citations

Aqueous Quaternary Ammonium Antiseptics and Disinfectants

1976 • 110 citations

The Effect of Currently Available Contact Lens Disinfection Systems on Acanthamoeba castellanii and Acanthamoeba polyphaga

1990 • 106 citations

Prevention and control of nosocomial infections

1987 • 106 citations

Asthma and Rhinitis after Exposure to Glutaraldehyde in Endoscopy Units

1986 • 105 citations

Contaminated Aqueous Benzalkonium Chloride

1976 • 104 citations

Salmonella newport infections transmitted by fiberoptic colonoscopy

1987 • 103 citations

BACTEREMIA CAUSED BY PSEUDOMONAS SP. FOLLOWING THE USE OF MATERIALS STORED IN SOLUTIONS OF A CATIONIC SURFACE-ACTIVE AGENT

1958 • 102 citations

Inactivation of Mycobacterium tuberculosis and Mycobacterium bovis by 14 hospital disinfectants

1991 • 102 citations

Contamination of Commercially Packaged Urinary Catheter Kits with the Pseudomonad EO-1

1970 • 101 citations

Alkalinized Glutaraldehyde, a New Antimicrobial Agent

1964 • 97 citations

Disinfection Practices for Endoscopes and Other Semicritical Items

1991 • 95 citations

Gram-negative water bacteria in hemodialysis systems.

1975 • 95 citations

Stability and inactivation of HTLV-III/LAV under clinical and laboratory environments

1986 • 95 citations

Outbreak of Serratia Marcescens Associated with the Flexible Fiberbronchoscope

1975 • 95 citations

PSEUDOMONAS AERUGINOSA PERITONITIS ASSOCIATED WITH CONTAMINATED POLOXAMER-IODINE SOLUTION

1982 • 94 citations

ANTIBIOTIC-SENSITIVE SERRATIA MARCESCENS INFECTIONS COMPLICATING CARDIOPULMONARY OPERATIONS: CONTAMINATED DISINFECTANT AS A RESERVOIR

1980 • 94 citations

Virucidal activity of disinfectants: studies with the poliovirus

1990 • 94 citations

Epidemic septic arthritis caused by Serratia marcescens and associated with a benzalkonium chloride antiseptic

1987 • 94 citations

Benzalkonium Chloride as a Source of Infection

1960 • 93 citations

Bactericidal activity of alkaline glutaraldehyde solution against a number of atypical mycobacterial species

1986 • 92 citations

Formaldehyde: evidence of carcinogenicity.

1981 • 91 citations

In-hospital evaluation of contamination of duodenoscopes: a quantitative assessment of the effect of drying

1991 • 85 citations

Serratia MarcescensMeningitis Associated With a Contaminated Benzalkonium Chloride Solution

1984 • 85 citations

Disinfecting endoscopes: how not to transmit Mycobacterium tuberculosis by bronchoscopy.

1980 • 83 citations

Cleaning and Disinfection of Fiberoptic Endoscopes: Evaluation of Glutaraldehyde Exposure Time and Forced-Air Drying

1982 • 81 citations

Benzalkonium Chloride—Source of Hospital Infection with Gram-Negative Bacteria

1961 • 80 citations

Disinfection, sterilization and preservation. 3rd edition.

1983 • 80 citations

The action of alcohols on rotavirus, astrovirus and enterovirus

1980 • 78 citations

Occupational contact dermatitis due to glutaraldehyde in health care workers

1988 • 78 citations

Antimicrobial and Other Properties of A New Stabilized Alkaline Glutaraldehyde Disinfectant/Sterilizer

1977 • 77 citations

Sporicidal activity of glutaraldehydes and hypochlorites and other factors influencing their selection for the treatment of medical equipment

1980 • 75 citations

Transposition of gentamicin resistance to staphylococcal plasmids encoding resistance to cationic agents

1984 • 75 citations

Recommendations for Preventing Transmission of Infection With Human T‐Lymphotropic Virus Type III/Lymphadenopathy‐Associated Virus in the Workplace

1986 • 74 citations

Mycobactericidal activity of glutaraldehyde solutions

1976 • 73 citations

The antibacterial properties of sodium hypochlorite and sodium dichloroisocyanurate as hospital disinfectants

1985 • 73 citations

Stability of sodium hypochlorite solutions

1982 • 72 citations

Modern Concept of Disinfection

1971 • 70 citations

Hydrogen peroxide enteritis: the “snow white” sign

1989 • 69 citations

Sterilization, disinfection, and antisepsis in the hospital

1991 • 68 citations

A more accurate method for measurement of tuberculocidal activity of disinfectants

1987 • 67 citations

Effect of methodology, dilution, and exposure time on the tuberculocidal activity of glutaraldehyde-based disinfectants

1990 • 67 citations

Occupational health services.

1972 • 61 citations

Proposal for a procedure for complete inactivation of the Creutzfeldt-Jakob disease agent

1991 • 59 citations

Tonometer disinfection and viruses.

1983 • 58 citations

Sterile Anesthesia Breathing Circuits Do Not Prevent Postoperative Pulmonary Infection

1981 • 58 citations

Types and Characteristics of Disinfectants

1967 • 57 citations

Guidelines for Hospital Environmental Control

1981 • 55 citations

Acquired immune deficiency syndrome (AIDS): precautions for clinical and laboratory staffs.

1982 • 54 citations

Disinfection of Goldmann Tonometers Against Human Immunodeficiency Virus Type 1

1989 • 53 citations

Sensitivity of methicillin‐resistant Staphylococcus aureus strains to some antibiotics, antiseptics and disinfectants

1988 • 53 citations

Ineffectiveness of Hospital Disinfectants Against Bacteria: A Collaborative Study

1987 • 53 citations

Epidemic Bloodstream Infections Associated with Pressure Transducers: A Persistent Problem

1989 • 53 citations

Manual Ventilation Bags as a Source for Bacterial Colonization of Intubated Patients

1990 • 52 citations

Epidemic Neonatal Hyperbilirubinemia and Use of a Phenolic Disinfectant Detergent

1978 • 52 citations

Industrial Sterilization

2013 • 51 citations

Prevalence of Antibody to Human Immunodeficiency Virus and Hepatitis B Surface Antigen in Blood Samples Submitted to a Hospital Laboratory

1987 • 50 citations

Rotavirus inactivation by chemical disinfectants and antiseptics used in hospitals

1983 • 50 citations

A comparison of hypochlorite and phenolic disinfectants for disinfection of clean and soiled surfaces and blood spillages

1989 • 47 citations

Recent advances in the cleaning and disinfection of fibrescopes

1981 • 47 citations

Iodine—Champagne in a Tin Cup

1982 • 46 citations

Epidemic Keratoconjunctivitis in a University Medical Center Ophthalmology Clinic; Need for Re-evaluation of the Design and Disinfection of Instruments

1989 • 46 citations

Comparison of sodium hypochlorite and sodium dichloroisocyanurate disinfectants: neutralization by serum

1988 • 45 citations

Infection Risks Associated with Spirometry

1991 • 45 citations

Efficacy of routine fiberoptic endoscope cleaning and disinfection for killing Clostridium difficile

1986 • 45 citations

Action of commonly used disinfectants against enteroviruses

1983 • 44 citations

Applanation Tonometer Tip Sterilization for Adenovirus Type 8

1987 • 43 citations

Quantitative neutralization assay of fungicidal activity of disinfectants

1987 • 43 citations

Use of membrane filters for measurement of mycobactericidal activity of alkaline glutaraldehyde solution

1987 • 42 citations

Mycobacterial cross-contamination of bronchoscopy specimens.

1982 • 41 citations

Sporicidal action of alkaline glutaraldehyde: factors influencing activity and a comparison with other aldehydes

1990 • 41 citations

A suspension method to determine reuse life of chemical disinfectants during clinical use

1988 • 41 citations

Disinfection of endoscopes

1986 • 40 citations

Laparoscopic procedures: The American Association of Gynecologic Laparoscopists' Membership Survey for 1975.

1977 • 39 citations

Alcohol as a Disinfectant against the Tubercle Bacillus

1947 • 39 citations

Viral transmission and fibreoptic endoscopy

1991 • 39 citations

Recovery of the human immunodeficiency virus from fibreoptic bronchoscopes.

1991 • 38 citations

FUNGICIDAL ACTION OF SOME COMMON DISINFECTANTS ON TWO DERMATOPHYTES

1933 • 38 citations

Bacteremia Following Cardiac Catheterization

1959 • 38 citations

Viability of Herpes Simplex Virus Type 1 on the Applanation Tonometer

1987 • 37 citations

Kinetics of the tuberculocidal response by alkaline glutaraldehyde in solution and on an inert surface

1986 • 37 citations

A comparison of sodium hypochlorite and sodium dichloroisocyanurate products

1985 • 37 citations

Potentiated acid 1,5 pentanedial solution--a new chemical sterilizing and disinfecting agent.

1974 • 36 citations

The activity of glutaraldehyde against Clostridium difficile

1985 • 36 citations

Contamination of endoscopes by species

1981 • 35 citations

Epistaxis Due to Glutaraldehyde Exposure

1989 • 35 citations

Analysis of plasmids mediating gentamicin resistance in methicillin-resistant Staphylococcus aureus

1984 • 35 citations

Inactivation of Human Immunodeficiency Virus by Betadine

1987 • 34 citations

Alcohol as a Surgical Disinfectant

1964 • 33 citations

Plasmid-Determined Resistance to Hexachlorophene in Pseudomonas aeruginosa

1978 • 33 citations

Acanthamoeba Keratitis and Contact Lens Wear

1990 • 32 citations

Evaluation of three disinfectants after in-use stress

1988 • 31 citations

The effects of some halogen‐containing compounds on Bacillus subtilis endospores

1991 • 31 citations

Sterilization of laparoscopes. Is soaking sufficient?

1979 • 31 citations

Influence of temperature on the synergistic sporicidal effect of peracetic acid plus hydrogen peroxide on Bacillus subtilis SA22 (NCA 72-52)

1984 • 31 citations

Bactericidal Effect of Hydrogen Peroxide on Spacecraft Isolates

1975 • 31 citations

Disinfection vs. sterilization of gynecologic laparoscopy equipment. The experience of the Phoenix Surgicenter.

1980 • 30 citations

Stability and Bactericidal Activity of Chlorine Solutions

1998 • 30 citations

Inactivation of the unconventional agents of scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease

1991 • 29 citations

Phenol and Neonatal Jaundice

1979 • 29 citations

Bacterial effect of hydrogen peroxide on urinary tract pathogens

1980 • 29 citations

Contaminated aqueous benzalkonium chloride. An unnecessary hospital infection hazard

1976 • 28 citations

Antitubercular Action of Disinfectants

1971 • 28 citations

A Complication from Alcohol-Swabbed Tonometer Tips

1988 • 28 citations

Comparison of the Activities and Stabilities of Alkaline Glutaraldehyde Sterilizing Solutions

1980 • 26 citations

Inactivation of human T-lymphotropic virus type III/lymphadenopathy-associated virus by formaldehyde-based reagents

1987 • 26 citations

Effectivity of Contact Lens Disinfection Systems Against Acanthamoeba culbertsoni

1991 • 26 citations

DISINFECTION OF VENTILATORS BY ULTRASONIC NEBULISATION

1968 • 26 citations

Disinfection of respirator tubing: a comparison of chemical versus hot water machine-assisted processing

1983 • 25 citations

Dialyser Reprocessing with Renalin®

1991 • 25 citations

A New Synergized Glutaraldehyde-Phenate Sterilizing Solution and Concentrated Disinfectant

1981 • 24 citations

Depigmentation caused by phenolic detergent germicides

1970 • 24 citations

Aqueous quaternary ammonium antiseptics and disinfectants. Use and misuse

1976 • 24 citations

The Bactericidal Effect of Surface-Active Agents on Tubercle Bacilli

1950 • 24 citations

A Note on the Fallacy of Using Alcohol for the Sterilization of Surgical Instruments

1923 • 23 citations

A Comparison of the Efficiency of Phenol, Liquor Cresolis, Formaldehyde, Sodium Hypochlorite and Sodium Hydroxide Against Eberthella Typhi at Various Temperatures

1936 • 22 citations

Disinfectant Testing Using a Modified Use-Dilution Method: Collaborative Study

1988 • 22 citations

Sensitization from contact with ethyl alcohol

1986 • 21 citations

An Efficacy Evaluation of a Synergized Glutaraldehyde-Phenate Solution in Disinfecting Respiratory Therapy Equipment Contaminated During Patient Use

1982 • 21 citations

Investigations on the sporicidal and fungicidal activity of disinfectants.

1985 • 21 citations

New technology for sterilization and disinfection

1991 • 20 citations

Virus transmission via fiberoptic endoscope: recommended disinfection.

1988 • 20 citations

Wescodyne: lack of activity against poliovirus in the presence of organic matter.

1978 • 19 citations

Investigations on rhinovirus inactivation by hydrogen peroxide.

1973 • 19 citations

Response of RP1+ and RP1− strains ofEscherichia coli to antibacterial agents and transfer of resistance toPseudomonas aeruginosa

1979 • 19 citations

Disinfection of Aerosolized Pathogenic Fungi on Laboratory Surfaces

1963 • 19 citations

INFECTION CONTROL IN INTENSIVE CARE

1976 • 19 citations

Epidermal toxicity of disinfectants.

1991 • 19 citations

Potentiated acid 1,5 pentanedial solution— a new chemical sterilizing and disinfecting agent

1974 • 19 citations

Studies on Disinfection of Clinical Thermometers

1953 • 18 citations

[Acute accidental poisoning with hospital disinfectant. 45 cases of which 13 with fatal outcome].

1991 • 18 citations

Hydrotherapy burn treatment: use of chloramine-T against resistant microorganisms.

1979 • 18 citations

Microbiologic evaluation of a new glutaraldehyde-based disinfectant for hemodialysis systems.

1982 • 18 citations

Disinfection of anaesthesia equipment by a mechanized pasteurization method

1975 • 17 citations

Guidelines for cleaning and disinfection of flexible fiberoptic endoscopes (FFE) used in Gl endoscopy

1978 • 17 citations

Dilution of glutaraldehyde by automatic endoscope machine washers: The need for a quality control program

1987 • 17 citations

Sterile Anesthesia Breathing Circuits Do Not Prevent Postoperative Pulmonary Infection

1982 • 17 citations

Evaluation of a New Disinfectant for Dialyzer Reuse

1989 • 17 citations

Comparison of dental surface disinfectants.

1987 • 17 citations

Use of sodium dichloroisocyanurate granules for spills of body fluids

1989 • 17 citations

Expanding Role of Hospital Epidemiology: Employee Health. Chemical Exposure in the Health Care Setting

1989 • 17 citations

A Comparative Investigation of the Bactericidal and Fungicidal Effects of Three Phenolic Disinfectants

1977 • 16 citations

70% Alcohol Disinfection of Transducer Heads: Experimental Trials

1985 • 16 citations

What standards should we use for the disinfection of large equipment?

1991 • 16 citations

Studies in sterilization of the laparoscope: II.

1979 • 16 citations

Effects of Disinfecting Solutions on Tonometer Tips

1990 • 16 citations

A hot water disinfection method for inhalation therapy equipment.

1969 • 16 citations

Disinfection of Aerosolized Pathogenic Fungi on Laboratory Surfaces

1963 • 16 citations

Studies on Disinfection of Clinical Thermometers

1953 • 15 citations

Assessment of ‘Cold Sterilog Glutaraldehyde Monitor’

1988 • 15 citations

An Examination of the Effect of Three Phenolic Disinfectants on Mycobacterium tuberculosis

1977 • 15 citations

Hazard: formaldehyde and hypochlorites

1977 • 15 citations

Infection control in intensive care

1988 • 15 citations

Bactericidal Effect of Hydrogen Peroxide on Spacecraft Isolates

1975 • 15 citations

A new method of disinfection of the flexible fibrebronchoscope.

1978 • 14 citations

The mycoplasmacidal properties of sodium hypochlorite

1985 • 14 citations

Disinfection of Immersion Tanks (Hubbard) in a Hospital Burn Unit

1974 • 14 citations

Bacteremia associated with reuse of disposable hollow-fiber hemodialyzers.

1986 • 14 citations

Clinical laboratory studies of disinfection with Sporicidin

1985 • 13 citations

Disinfection or sterilization?

1983 • 12 citations

Disinfection of Aerosolized Pathogenic Fungi on Laboratory Surfaces

1964 • 11 citations

Brief Report: Inactivation of Herpesvirus on CPR Manikins Utilizing a Currently Recommended Disinfecting Procedure

1985 • 10 citations

Safe and Cost-Effective Cleaning of Pressure-Monitoring Transducers

1988 • 9 citations

Laboratory Studies on Disinfection of Oral Thermometers

1952 • 8 citations

Clinical evaluation of ColdSpor, a glutaraldehyde-phenolic disinfectant.

1991 • 8 citations

[Transmissible formaldehyde resistance in Serratia marcescens].

1985 • 8 citations

Laboratory Studies on Disinfection of Rectal Thermometers

1953 • 7 citations

A discussion: laparoscopic instrument sterilization.

1977 • 7 citations

Inactivation of Human T-Cell Lymphotropic Retrovirus (HTLV-III) by LdTm

1985 • 7 citations

Occupational exposures to formaldehyde in dialysis units.

1986 • 6 citations

A hot water disinfection method for inhalation therapy equipment

1970 • 6 citations

Symptoms of irritation associated with exposure to glutaraldehyde--Colorado.

1987 • 5 citations

Recommendations for Decontaminating Manikins Used in Cardiopulmonary Resuscitation Training 1983 Update

1984 • 3 citations

Formaldehyde exposures in a gross anatomy laboratory--Colorado.

1983 • 3 citations

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APIC guideline for selection and use of disinfectants (1990) – American Journal of Infection Control | Metascience Observatory Explorer