The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

Maximum Likelihood from Incomplete Data Via the EM Algorithm

1977 • 46,601 citations

Inflammation in atherosclerosis

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Coronary Plaque Disruption

1995 • 3,542 citations

Parametric and nonparametric linkage analysis: a unified multipoint approach.

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Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

A high-resolution recombination map of the human genome

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Allele-Sharing Models: LOD Scores and Accurate Linkage Tests

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Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

2002 • 942 citations

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Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

1990 • 777 citations

Prediction of the Risk of Myocardial Infarction from Polymorphisms in Candidate Genes

2002 • 657 citations

Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations

1987 • 630 citations

Arachidonate 5-Lipoxygenase Promoter Genotype, Dietary Arachidonic Acid, and Atherosclerosis

2003 • 620 citations

White Cell Telomere Length and Risk of Premature Myocardial Infarction

2003 • 584 citations

The gene encoding phosphodiesterase 4D confers risk of ischemic stroke

2003 • 569 citations

A Haplotype-Based Haplotype Relative Risk’ Approach to Detecting Allelic Associations

1992 • 502 citations

Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

2003 • 457 citations

Identification of 5-Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice

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Mutation of MEF2A in an Inherited Disorder with Features of Coronary Artery Disease

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World Heart Day 2002

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A Class of Tests for Linkage Using Affected Pedigree Members

1994 • 346 citations

A comprehensive linkage analysis for myocardial infarction and its related risk factors

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Leukotriene B4 in inflammation.

1990 • 294 citations

Single Nucleotide Polymorphisms in Multiple Novel Thrombospondin Genes May Be Associated With Familial Premature Myocardial Infarction

2001 • 291 citations

THE INTERACTION OF SELECTION AND LINKAGE. II. OPTIMUM MODELS

1964 • 281 citations

Changes in the endothelium of the aorta and the behaviour of macrophages in experimental atheroma of rabbits

1958 • 270 citations

A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27

2001 • 265 citations

Leukotriene B4 Receptor Antagonism Reduces Monocytic Foam Cells in Mice

2002 • 251 citations

Localization of a Susceptibility Gene for Common Forms of Stroke to 5q12

2002 • 204 citations

Angioplasty triggers intracoronary leukotrienes and lipoxin A4. Impact of aspirin therapy.

1992 • 194 citations

Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils.

1990 • 180 citations

Leukotrienes C4, D4 and E4: effects on human and guinea-pig cardiac preparations in vitro.

1982 • 178 citations

Two Loci on Chromosomes 2 and X for Premature Coronary Heart Disease Identified in Early- and Late-Settlement Populations of Finland

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Genome-Wide Linkage Analysis of the Acute Coronary Syndrome Suggests a Locus on Chromosome 2

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Fluorescence energy transfer detection as a homogeneous DNA diagnostic method

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Protection of privacy by third-party encryption in genetic research in Iceland

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THE EFFECTS OF INBREEDING AT LOCI WITH HETEROZYGOTE ADVANTAGE

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Release of Leukotriene A4 Leukotriene B4 from Human Polymorphonuclear Leukocytes

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Leukotriene C4 production by murine mast cells: evidence of a role for extracellular leukotriene A4.

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Studies on the mechanism of leukotriene induced coronary artery constriction

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Localization of a Gene for Peripheral Arterial Occlusive Disease to Chromosome 1p31

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Distribution of Tissue Plasminogen Activator Insertion/Deletion Polymorphism in Myocardial Infarction and Control Subjects

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Inflammatory infiltrates in human coronary atherosclerosis

1986 • 42 citations

Reduction in blood flow in normal and narrowed coronary arteries of dogs by leukotriene C4

1985 • 29 citations

Novel Polymorphism of the 5-Lipoxygenase Activating Protein (FLAP) Promoter Gene Associated with Asthma

1999 • 29 citations

Deleted Work

1955 • 0 citations