Bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck.

Green Fluorescent Protein as a Marker for Gene Expression

1994 • 6,572 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1992 • 871 citations

Scrape-loading and dye transfer

1987 • 669 citations

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

1989 • 596 citations

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

1990 • 502 citations

In VitroEvidence That Metabolic Cooperation Is Responsible for the Bystander Effect Observed with HSVtkRetroviral Gene Therapy

1993 • 425 citations

Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins.

1996 • 418 citations

Intercellular calcium signaling via gap junctions in glioma cells.

1992 • 316 citations

Gap junctional communication and carcinogenesis

1990 • 310 citations

Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid

1986 • 302 citations

In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma.

1995 • 262 citations

Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus.

1994 • 247 citations

Gap junction function and cancer.

1993 • 214 citations

A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis

1994 • 195 citations

Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells.

1996 • 188 citations

The role of gap junction membrane channels in development

1996 • 158 citations

p53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy

1997 • 122 citations

Stable Expression of the Wild-Typep53Gene in Human Lung Cancer Cells after Retrovirus-Mediated Gene Transfer

1993 • 121 citations

Cell‐cell communication and growth control of normal and cancer cells: Evidence and hypothesis

1993 • 95 citations

Effect of Herpes Simplex Virus Thymidine Kinase Expression Levels on Ganciclovir-Mediated Cytotoxicity and the “Bystander Effect”

1995 • 92 citations

Phenotypic Expression of Transformation: Induction in Cell Culture by a Phorbol Ester

1967 • 90 citations

Bystander Tumoricidal Effect in the Treatment of Experimental Brain Tumors

1994 • 88 citations

Bystander effect caused by suicide gene expression indicates the feasibility of gene therapy for hepatocellular carcinoma

1995 • 64 citations

A tumor suppressor gene, Cx26, also mediates the bystander effect in HeLa cells.

1997 • 60 citations