Dicoumarol-induced prothrombins containing 6, 7, and 8 γ-carboxyglutamic acid residues: isolation and characterization

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane

1971 • 8,619 citations

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

Vitamin K Dependent Modifications of Glutamic Acid Residues in Prothrombin

1974 • 750 citations

The role of phospholipids and factor Va in the prothrombinase complex.

1980 • 672 citations

The contribution of bovine Factor V and Factor Va to the activity of prothrombinase.

1979 • 592 citations

The Mode of Action of Vitamin K

1974 • 527 citations

Two-stage Procedure For the Quantitative Determination of Prothrombin Concentration*

1949 • 379 citations

Primary structure of the vitamin K-dependent part of prothrombin

1974 • 289 citations

Differentiation of metal ion-induced transitions of prothrombin fragment 1.

1977 • 235 citations

Acquired Vitamin K-Dependent Carboxylation Deficiency in Liver Disease

1981 • 224 citations

Role of gamma-carboxyglutamic acid. Cation specificity of prothrombin and factor X-phospholipid binding.

1976 • 152 citations

Vitamin K and the Biosynthesis of Prothrombin

1972 • 146 citations

Plasma prothrombin during treatment with Dicumarol. II. Demonstration of an abnormal prothrombin fraction.

1968 • 145 citations

The Purification and Properties of an Abnormal Prothrombin Protein Produced by Dicumarol-treated Cows

1972 • 141 citations

The kinetics of activation of normal and gamma-carboxyglutamic acid-deficient prothrombins.

1985 • 131 citations

The Conversion of Prothrombin to Thrombin

1974 • 124 citations

Prothrombin requires two sequential metal-dependent conformational transitions to bind phospholipid. Conformation-specific antibodies directed against the phospholipid-binding site on prothrombin.

1986 • 124 citations

The Conversion of Prothrombin to Thrombin

1974 • 78 citations

Immunoassays of human prothrombin species which correlate with functional coagulant activities.

1983 • 77 citations

Conformation-specific antibodies as probes of the gamma-carboxyglutamic acid-rich region of bovine prothrombin. Studies of metal-induced structural changes.

1979 • 61 citations

Conformation-specific antibodies directed against the bovine prothrombin . calcium complex.

1980 • 59 citations

Metal and phospholipid binding properties of partially carboxylated human prothrombin variants.

1985 • 59 citations

Comparison of the native prothrombin antigen and the prothrombin time for monitoring oral anticoagulant therapy

1984 • 53 citations

Isolation and purification of bovine and canine prothrombin

1965 • 44 citations

Antibodies directed against a gamma-carboxyglutamic acid-rich region of bovine prothrombin. Preparation, isolation, and characterization.

1978 • 42 citations

Distribution of gamma-carboxyglutamic acid residues in partially carboxylated human prothrombins.

1986 • 41 citations

Rapid assay for γ-carboxyglutamic acid in urine and bone by precolumn derivatization and reversed-phase liquid chromatography

1984 • 35 citations

Human Coumarin Prothrombin

1973 • 24 citations

The relationship between protein-protein and protein-lipid interactions and the immunological properties of bovine prothrombin and several of its fragments.

1982 • 18 citations

Partially carboxylated prothrombins I. Comparison of activation properties and purification of 1- and 0-carboxyglutamyl variants

1982 • 18 citations

Atypical prothrombin in purified preparations from dicoumarol-treated steers

1972 • 15 citations

Structural and physiological relationships in blood clotting proteins: thrombin and prothrombin

1979 • 9 citations

Kinetic and equilibrium metal-ion-binding behaviour reflected in a metal-ion-dependent antigenic determinant in bovine prothrombin. Comparison with bovine prothrombin fragment 1

1981 • 8 citations

5 Mechanisms of vitamin K antagonism

1990 • 8 citations