Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture

Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication.

1979 • 1,136 citations

Nucleosides as Biological Probes

1979 • 218 citations

Purine metabolism in Leishmania donovani and Leishmania braziliensis

1978 • 204 citations

A Simple Monophasic Medium for Axenic Culture of Hemoflagellates

1976 • 201 citations

Pyrazolopyrimidine metabolism in the pathogenic trypanosomatidae

1983 • 107 citations

Purine metabolism in Trypanosoma cruzi

1981 • 83 citations

Biological action of inosine analogs in Leishmania and Trypanosoma spp

1984 • 73 citations

Purine nucleoside phosphorylase from human erythrocytes. 3. Inhibition by the inosine analog formycin B of the isolated enzyme and of nucleoside metabolism in intact erythrocytes and sarcoma 180 cells.

1968 • 68 citations

Influence of formycin B on polyadenosine diphosphoribose synthesis in vitro and in vivo.

1975 • 57 citations

Purine metabolism in the bloodstream forms of trypanosoma gambiense and Trypanosoma rhodesiense

1982 • 56 citations

Antileishmanial action of 4-thiopyrazolo (3,4-d)pyrimidine and its ribonucleoside

1982 • 46 citations

Purine metabolism in Trypanosoma brucei gambiense

1982 • 41 citations

Activity of purine analogs against Leishmania tropica within human macrophages in vitro

1983 • 35 citations

Monophosphates of formycin B and allopurinol riboside

1984 • 28 citations

Primary Murine Bone Marrow Cultures Support Continuous Growth of Infectious Human Trypanosomes

1983 • 26 citations

Pyrazolopyrimidine metabolism in African trypanosomes: Metabolic similarities to Trypanosoma cruzi and Leishmania spp.

1980 • 24 citations

Efficacy of Pyrazolopyrimidine Ribonucleosides Against Irypanosoma cruzi: Studies in Vitro and in Vivo with Sensitive and Resistant Strains

1984 • 22 citations

Metabolism of formycin B by Leishmania amastigotes in vitro. Comparative metabolism in infected and uninfected human macrophages.

1983 • 19 citations

Effects of 8-azaadenosine and formycin on cell lethality and the synthesis and methylation of nucleic acids in human colon carcinoma cells in culture

1982 • 15 citations