Contribution of organic anion transporting polypeptide to uptake of its possible substrates into rat hepatocytes.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1991 • 5,120 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Expression cloning of a rat liver Na(+)-independent organic anion transporter.

1994 • 535 citations

Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.

1991 • 479 citations

Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.

1994 • 444 citations

Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver

1995 • 419 citations

Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain

1997 • 396 citations

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport

1995 • 385 citations

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR

1997 • 294 citations

N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein.

1993 • 209 citations

Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile

1995 • 186 citations

Immunologic distribution of an organic anion transport protein in rat liver and kidney

1996 • 182 citations

Functional characterization of the basolateral rat liver organic anion transporting polypeptide

1994 • 158 citations

Na(+)-independent multispecific anion transporter mediates active transport of pravastatin into rat liver

1993 • 154 citations

Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver.

1996 • 152 citations

Regulation of 2‐acetylaminofluorene‐and 3‐methylcholanthrene‐mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver

1991 • 125 citations

Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes

1996 • 120 citations

Carrier-mediated transport of ouabain in isolated hepatocytes.

1978 • 116 citations

Parallel decrease of Na+ -taurocholate cotransport and its encoding mRNA in primary cultures of rat hepatocytes

1993 • 104 citations

Influence of Cl- on organic anion transport in short-term cultured rat hepatocytes and isolated perfused rat liver.

1987 • 88 citations

Transport Polarity of Hepatocytes

1988 • 88 citations

Estradiol 17 beta-D-glucuronide is a high-affinity substrate for oatp organic anion transporter

1996 • 79 citations

Contribution of sodium taurocholate co-transporting polypeptide to the uptake of its possible substrates into rat hepatocytes.

1998 • 76 citations

Kinetics of Hepatic Uptake of Unconjugated Bilirubin

1976 • 68 citations

Transport of dibromosulphthalein by isolated rat hepatocytes

1981 • 53 citations

Uptake of benzylpenicillin, cefpiramide and cefazolin by freshly prepared rat hepatocytes

1986 • 53 citations

Evaluation of the uptake of pravastatin by perfused rat liver and primary cultured rat hepatocytes.

1995 • 44 citations

Effects of inhibitors of Na+-coupled ion transport on bile acid uptake by isolated rat hepatocytes

1982 • 44 citations

Reconstitution of bile acid transport in the rat hepatoma McArdle RH- 7777 cell line

1996 • 36 citations

Novel Dual Inhibitors of 5-Lipoxygenase and Thromboxane A2 Synthetase: Synthesis and Structure-Activity Relationships of 3-Pyridylmethyl-Substituted 2-Amino-6-hydroxybenzothiazole Derivatives

1994 • 34 citations

ATP-dependent Efflux of 2,4-Dinitrophenyl-S-glutathione

1995 • 34 citations

Uptake of bumetanide into isolated rat hepatocytes and primary liver cell cultures

1989 • 27 citations

Carrier-mediated active transport of BQ-123, a peptidic endothelin antagonist, into rat hepatocytes.

1996 • 27 citations

Different relationships between cellular ATP and hepatic uptake among taurocholate, cholate, and organic anions

1993 • 26 citations

Multiple carriers for uptake of [3H]estradiol-17 beta(beta-D-glucuronide) in isolated rat hepatocytes.

1987 • 24 citations

Carrier-mediated active transport of the glucuronide and sulfate of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into rat liver: quantitative comparison of permeability in isolated hepatocytes, perfused liver and liver in vivo.

1997 • 20 citations

Effects of Organic Anions on the Uptake of 1-Anilino-8-naphthalenesulfonate by Isolated Liver Cells

1983 • 16 citations

What we have learned about bumetanide and the concept of multispecific bile acid/drug transporters from the liver.

1996 • 12 citations

Carrier-mediated electrogenic transport of estradiol-17 beta-glucuronide in rat liver BMV

1994 • 8 citations