PRIOR INDUCTION OF HEAT SHOCK PROTEINS BY A NITRIC OXIDE DONOR ATTENUATES CARDIAC ISCHEMIA/REPERFUSION INJURY IN THE RAT1

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes.

1972 • 3,187 citations

Nitric oxide: an endogenous modulator of leukocyte adhesion.

1991 • 3,079 citations

THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger Gases

1997 • 2,481 citations

Improved technique of heart transplantation in rats

1969 • 1,338 citations

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

1989 • 1,273 citations

Biosynthesis of nitric oxide from l-arginine

1989 • 1,220 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Isolation and Characterization of a cDNA from the Rat Brain that Encodes Hemoprotein Heme Oxygenase‐3

1997 • 834 citations

Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

1988 • 741 citations

The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression.

1992 • 525 citations

Heat-shock protein induction in rat hearts. A direct correlation between the amount of heat-shock protein induced and the degree of myocardial protection.

1994 • 364 citations

Role of the Tricuspid Annulus and the Eustachian Valve/Ridge on Atrial Flutter

1996 • 363 citations

Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels.

1995 • 340 citations

NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium

1996 • 326 citations

Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury

1992 • 312 citations

Thiol Compounds Interact with Nitric Oxide in Regulating Heme Oxygenase-1 Induction in Endothelial Cells

1997 • 297 citations

Heat-shock response and limitation of tissue necrosis during occlusion/reperfusion in rabbit hearts.

1993 • 278 citations

Cobalt Induction of Hepatic Heme Oxygenase; with Evidence That Cytochrome P -450 Is Not Essential for This Enzyme Activity

1974 • 261 citations

Nitrogen oxide‐induced autoprotection in isolated rat hepatocytes

1995 • 211 citations

Effects of acidosis on phosphorylation of phospholamban and troponin I in rat cardiac muscle

1996 • 209 citations

Superoxide Modulates the Oxidation and Nitrosation of Thiols by Nitric Oxide-derived Reactive Intermediates

1997 • 187 citations

Molecular adaptation of vascular endothelial cells to oxidative stress

1993 • 182 citations

Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin.

1995 • 170 citations

Inhibition of Nitric Oxide Limits Infarct Size in the in Situ Rabbit Heart

1993 • 160 citations

Nitric oxide induces heat-shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1.

1997 • 144 citations

Cardiac preservation is enhanced in a heterotopic rat transplant model by supplementing the nitric oxide pathway.

1994 • 141 citations

Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism

1971 • 131 citations

Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart

1994 • 123 citations

Myocardial protection after whole body heat stress in the rabbit is dependent on metabolic substrate and is related to the amount of the inducible 70-kD heat stress protein.

1994 • 120 citations

The balance between nitric oxide and superoxide determines apoptotic and necrotic death of rat mesangial cells.

1997 • 105 citations

Heme oxygenase-1 induction in skeletal muscle cells: hemin and sodium nitroprusside are regulators in vitro

1998 • 79 citations

Beneficial effects of SPM-5185, a cysteine-containing NO donor in myocardial ischemia-reperfusion

1992 • 74 citations

Nitric oxide protects endothelial cells from tumor necrosis factor‐α‐mediated cytotoxicity: possible involvement of cyclic GMP

1997 • 69 citations

Differential Accumulation of mRNA for Immediate Early Genes and Heat Shock Genes in Heart After Ischaemic Injury

1996 • 55 citations

Mitochondrial Mass and Membrane Potential in Celomocytes from the Earthworm Eisenia foetida: Studies with Fluorescent Probes in Single Intact Cells

1995 • 41 citations

Critical timing of nitric oxide supplementation in cardioplegic arrest and reperfusion.

1996 • 36 citations

Close correlation of the cardioprotective effect of FK409, a spontaneous NO releaser, with an increase in plasma cyclic GMP level

1994 • 27 citations

Common Antigenicity between Yersinia enterocolitica-Derived Heat-Shock Protein and the Retina, and Its Role in Uveitis

1996 • 18 citations

Effect of l-arginine cardioplegia on recovery of neonatal lamb hearts after 2 hours of cold ischemia

1995 • 15 citations

Nitric Oxide Release from the Liver Surface to the Intraabdominal Cavity during Acute Endotoxemia in Rats

1998 • 13 citations

Nitric oxide donor induces upregulation of stress proteins in cold ischemic rat hearts

1999 • 8 citations

FK409: A New Vasodilator with Nitric Oxide‐donating Ability

1994 • 8 citations

Beneficial Impact of FK 409 As Donor Pretreatment on Warm or Cold Ischemically Injured Hearts in the Rat

1998 • 4 citations