Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

Ovarian development in Drosophila melanogaster

1970 • 1,436 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

Determination of Anteroposterior Polarity in Drosophila

1987 • 651 citations

The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4A

1988 • 625 citations

A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases

1988 • 602 citations

Characterization and cloning of fasciclin III: A glycoprotein expressed on a subset of neurons and axon pathways in Drosophila

1987 • 545 citations

Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophila

1986 • 463 citations

Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryo

1986 • 449 citations

tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster

1985 • 401 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Female sterile mutations on the second chromosome of Drosophila melanogaster. I. Maternal effect mutations.

1989 • 360 citations

The Drosophila posterior-group gene nanos functions by repressing hunchback activity

1989 • 301 citations

hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo

1987 • 289 citations

The segmentation and homeotic gene network in early Drosophila development

1987 • 286 citations

Fine structure of pole cells and polar granules in Drosophila melanogaster

1962 • 274 citations

POLYCOMBLIKE: A GENE THAT APPEARS TO BE REQUIRED FOR THE NORMAL EXPRESSION OF THE BITHORAX AND ANTENNAPEDIA GENE COMPLEXES OF DROSOPHILA MELANOGASTER

1982 • 258 citations

Polar granules of Drosophila. II. Ultrastructural changes during early embryogenesis

1968 • 250 citations

Identification of a component ofDrosophilapolar granules

1988 • 247 citations

cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo.

1989 • 246 citations

Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos

1989 • 222 citations

Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps

1988 • 217 citations

Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene

1989 • 198 citations

Structure of the Drosophila BicaudalD protein and its role in localizing the posterior determinant nanos

1989 • 185 citations

DOMINANT MATERNAL-EFFECT MUTATIONS OF DROSOPHILA MELANOGASTER CAUSING THE PRODUCTION OF DOUBLE-ABDOMEN EMBRYOS

1986 • 184 citations

Bicaudal-D, a Drosophila gene involved in developmental asymmetry: localized transcript accumulation in ovaries and sequence similarity to myosin heavy chain tail domains.

1989 • 178 citations

Accurate measurements of dynamics and reproducibility in small genetic networks

2013 • 174 citations

X-LINKED FEMALE-STERILE LOCI IN DROSOPHILA MELANOGASTER

1986 • 162 citations

Involvement of the pumilio gene in the transport of an abdominal signal in the Drosophila embryo

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Polar granules of Drosophila. IV. Cytochemical studies showing loss of RNA from polar granules during early stages of embryogenesis

1971 • 133 citations

Bicaudal, a genetic factor which affects the polarity of the embryo in Drosophila melanogaster

1966 • 132 citations

Dorsal—ventral embryonic pattern genes of Drosophila

1987 • 128 citations

Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis

1989 • 120 citations

Genetic analysis of pattern-formation in the embryo ofDrosophila melanogaster

1977 • 115 citations

THE GENETICS OF DOPA DECARBOXYLASE IN DROSOPHILA MELANOGASTER I. ISOLATION AND CHARACTERIZATION OF DEFICIENCIES THAT DELETE THE DOPA-DECARBOXYLASE-DOSAGE-SENSITIVE REGION AND THE α-METHYL-DOPA-HYPERSENSITIVE LOCUS

1976 • 100 citations

Developmental morphology of polar granules in Drosophila. Including observations on pole cell behavior and distribution during embryogenesis

1963 • 88 citations

A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster

1985 • 74 citations

Developmental analysis of the torso-like phenotype in Drosophila produced by a maternal-effect locus

1986 • 68 citations

Nitrocellulose-bound antigen repeatedly used for the affinity purification of specific polyclonal antibodies for screening DNA expression libraries

1988 • 60 citations

THE GENETICS OF A SMALL AUTOSOMAL REGION OF DROSOPHILA MELANOGASTER, INCLUDING THE STRUCTURAL GENE FOR ALCOHOL DEHYDROGENASE. V. CHARACTERIZATION OF X-RAY-INDUCED Adh NULL MUTATIONS

1982 • 58 citations

Three distinct distributions of F-actin occur during the divisions of polar surface caps to produce pole cells in Drosophila embryos.

1985 • 50 citations

The egg came first, of course!

1989 • 49 citations

Differentiation within the gonads of Drosophila revealed by immunofluorescence

1981 • 42 citations

Phenotypic comparison between maternal and zygotic genes controlling the segmental pattern of the Drosophila embryo

1988 • 36 citations

THE GENETICS OF A SMALL CHROMOSOME REGION OF DROSOPHILA MELANOGASTER CONTAINING THE STRUCTURAL GENE FOR ALCOHOL DEHYDROGENASE. IV: SCUTOID, AN ANTIMORPHIC MUTATION

1982 • 27 citations

TISSUE-SPECIFIC AND COMPLEX COMPLEMENTATION PATTERNS IN THE PUNCH LOCUS OF DROSOPHILA MELANOGASTER

1985 • 25 citations

Segmental polarity and identity in the abdomen of Drosophila is controlled by the relative position of gap gene expression

1989 • 18 citations