Pathways of Spindle Pole Formation: Different Mechanisms; Conserved Components

Beyond self-assembly: From microtubules to morphogenesis

1986 • 1,334 citations

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

1996 • 978 citations

Nucleation of microtubule assembly by a γ-tubulin-containing ring complex

1995 • 851 citations

Microtubule assembly nucleated by isolated centrosomes

1984 • 775 citations

Mitotic spindle organization by a plus-end-directed microtubule motor

1992 • 643 citations

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.

1996 • 634 citations

A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly

1996 • 565 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

Cytoplasmic dynein is localized to kinetochores during mitosis

1990 • 486 citations

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.

1995 • 466 citations

Sites of microtubule assembly and disassembly in the mitotic spindle

1986 • 410 citations

A bipolar kinesin

1996 • 365 citations

Affinity Chromatography Demonstrates a Direct Binding between Cytoplasmic Dynein and the Dynactin Complex

1995 • 338 citations

Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization

1997 • 335 citations

Interpolar spindle microtubules in PTK cells.

1993 • 318 citations

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

1996 • 301 citations

Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein.

1991 • 300 citations

Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein.

1996 • 249 citations

NuMA is required for the organization of microtubules into aster-like mitotic arrays.

1995 • 242 citations

γ-Tubulin is present in acentriolar MTOCs during early mouse development

1993 • 238 citations

Xklp15 a chromosomal xenopus kinesin-like protein essential for spindle organization and chromosome positioning

1995 • 237 citations

Centrosomes and mitotic poles

1984 • 229 citations

Mitotic Spindle Poles are Organized by Structural and Motor Proteins in Addition to Centrosomes

1997 • 220 citations

The motor for poleward chromosome movement in anaphase is in or near the kinetochore.

1989 • 202 citations

Xklp2, a Novel Xenopus Centrosomal Kinesin-like Protein Required for Centrosome Separation during Mitosis

1996 • 159 citations

DNA binding and meiotic chromosomal localization of the drosophila nod kinesin-like protein

1995 • 147 citations

Chromokinesin: a DNA-binding, kinesin-like nuclear protein.

1995 • 132 citations

Monastral bipolar spindles: implications for dynamic centrosome organization

1997 • 84 citations

NuMA assembles into an extensive filamentous structure when expressed in the cell cytoplasm

1996 • 74 citations

Ability to organize microtubules in taxol-treated mitotic PtK2 cells goes with the SPN antigen and not with the centrosome

1992 • 59 citations

Mechanically cut mitotic spindles: clean cuts and stable microtubules

1989 • 51 citations

Microtubule dynamics investigated by microinjection of Paramecium axonemal tubulin: lack of nucleation but proximal assembly of microtubules at the kinetochore during prometaphase.

1989 • 46 citations

Nucleation of Microtubule Assembly

1986 • 11 citations