T Cell-Derived Antigen Binding Molecules (TABM): Molecular and Functional Properties

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

Immunoregulatory T-Cell Pathways

1983 • 308 citations

Regulation of IgE Synthesis

1984 • 301 citations

The Role of Antigen-Specific T Cell Factors in the Immune Response

1980 • 250 citations

Specific antigen—la activation of transfected human T cells expressing murine Ti αβ —human T3 receptor complexes

1987 • 247 citations

Predominant use of a Vα gene segment in mouse T-cell receptors for cytochrome c

1986 • 206 citations

T‐Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State

1987 • 190 citations

Sequence and expression of transcripts of the T-cell antigen receptor alpha-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma.

1986 • 118 citations

Rearrangement and transcription of a T-cell receptor beta-chain gene in different T-cell subsets.

1985 • 110 citations

Antigen-specific t lymphocyte clones. II. Purifcation and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells

1981 • 103 citations

Functional and molecular organisation of an antigen-specific suppressor factor from a T-cell hybridoma

1980 • 92 citations

Binding of antigen in the absence of histocompatibility proteins by arsonate-reactive T-cell clones

1984 • 86 citations

Mast cell activation and vascular alterations in immediate hypersensitivity-like reactions induced by a T cell-derived antigen-binding factor.

1984 • 82 citations

T cells produce an antigen-binding factor with in vivo activity analogous to IgE antibody.

1983 • 78 citations

Direct evidence for the existence of nominal antigen binding sites on T cell surface Ti α-β heterodimers of MHC-restricted T cell clones

1986 • 77 citations

CORRELATIONS BETWEEN PLASMA PROTEIN FRACTIONS, ANTIBODY TITERS, AND THE PASSIVE TRANSFER OF DELAYED AND IMMEDIATE CUTANEOUS REACTIVITY TO TUBERCULIN PPD AND TUBERCULOPOLYSACCHARIDES

1955 • 63 citations

An arthritogenic lymphokine in the rat.

1985 • 60 citations

Analysis of T cell hybridomas. I. Characterization of H-2 and Igh-restricted monoclonal suppressor factors.

1981 • 60 citations

Analysis of T cell hybridomas. II. Comparisons among three distinct types of monoclonal suppressor factors.

1981 • 51 citations

Reconstitution of antigen-specific suppressor activity with translation products of mRNA

1982 • 51 citations

Molecular composition of an antigen-specific, Ly-1 T suppressor inducer factor. One molecule binds antigen and is I-J-; another is I-J+, does not bind antigen, and imparts an Igh-variable region-linked restriction.

1982 • 48 citations

Epidermal cells in activation of suppressor lymphocytes: further characterization.

1987 • 43 citations

Genetically restricted antigen presentation for immunological tolerance and suppression

1984 • 43 citations

Isolation and characterization of a T suppressor factor by using a monoclonal antibody.

1985 • 37 citations

Purification and biochemical analysis of antigen-specific suppressor factors obtained from the supernatant, membrane, or cytosol of a T cell hybridoma.

1983 • 36 citations

Isolation and characterization of an antigen-specific suppressor inducer molecule from serum of hyperimmune mice by using a monoclonal antibody.

1986 • 35 citations

Reconstitution of an inactive antigen-specific T cell suppressor factor by incubation of the factor with prostaglandins.

1984 • 34 citations

Antigen‐specific suppressor factors produced by T cell hybridomas for delayed‐type hypersensitivity

1979 • 33 citations

Evidence for two suppressor factors secreted by a single cell suggests a solution to the J-locus paradox.

1983 • 33 citations

Transfer of an antigen-specific immediate hypersensitivity-like reaction with an antigen-binding factor produced by T cells.

1982 • 33 citations

IgE-binding factors from mouse T lymphocytes. III. Role of antigen-specific suppressor T cells in the formation of IgE-suppressive factor.

1984 • 31 citations

The I-J Puzzle

1987 • 30 citations

Equivalence of conventional anti-picryl T suppressor factor in the contact sensitivity system and monoclonal anti-NP TsF3: their final non-specific effect via the T acceptor cell.

1984 • 28 citations

Suppressor factor from a T cell hybrid inhibits delayed-type hypersensitivity responses to azobenzenearsonate.

1981 • 27 citations

I‐J as an Inducible T Cell Receptor for Self

1985 • 27 citations

Interactions between molecules (subfactors) released by different T cell sets that yield a complete factor with biological (suppressive) activity.

1982 • 25 citations

Major histocompatibility complex-restricted and unrestricted activation of helper T cell lines by liposome-bound antigens.

1986 • 25 citations

Immune serum from mice contact‐sensitized with picryl chloride contains an antigen‐specific T cell factor that transfers immediate cutaneous reactivity

1986 • 24 citations

Hapten-specific responses to the phenyltrimethylamino hapten. V. A single chain antigen-binding I-J+ first-order T suppressor factor requires antigen to induce anti-idiotypic second-order suppressor T cells.

1985 • 24 citations

Macrophage handling of a tolerogen and the role of IL 1 in tolerance induction in a helper T cell clone in vitro.

1987 • 23 citations

Interaction of antigen-specific T cell factors with unique "receptors" on the surface of mast cells: demonstration in vitro by an indirect rosetting technique.

1986 • 22 citations

Antigen-specific molecules from murine T lymphocytes and T cell hybridomas

1980 • 22 citations

Purification and characterization of TNP-specific immunoregulatory molecules produced by T cells sensitized by picrylchloride (PC1F).

1983 • 21 citations

Regulation of immune responses by I-J gene products. III. GT-specific suppressor factor is composed of separate I-J and idiotype-bearing chains.

1983 • 20 citations

An antigen-specific helper T cell hybridoma produces an antigen-specific suppressor inducer molecule with identical antigenic fine specificity. Implications for the antigen recognition and function of helper and suppressor inducer T cells.

1988 • 20 citations

Functional roles of two polypeptide chains that compose an antigen-specific suppressor T cell factor.

1984 • 20 citations

Chemical features of an antigen-specific suppressor T cell factor composed of two polypeptide chains.

1984 • 19 citations

STUDIES ON CYTOPHILIC ANTIBODIES

1970 • 19 citations

Production and purification of monoclonal T lymphocyte antigen binding molecules (TABM)

1984 • 18 citations

Messenger RNA for an antigen-specific binding molecule from an antigen-specific T-cell hybrid.

1984 • 18 citations

Igh variable region-restricted T cell interactions. Genetic restriction of an antigen-specific suppressor inducer factor is imparted by an I-J+ antigen-nonspecific molecule.

1983 • 18 citations

Quantitation of T cell antigen-binding molecules (TABM) in the sera of nonimmunized, immunized, and desensitized mice.

1987 • 18 citations

Isolation of an antigen-specific T suppressor factor that suppresses the in vivo response of DBA/2 mice to ferredoxin.

1987 • 17 citations

Analysis of hapten-specific T suppressor factors: genetic restriction of TsF1 activity analyzed with synthetic hybrid suppressor molecules.

1984 • 16 citations

Antigen-binding molecules of T-cells: Charge heterogeneity and structural lability

1985 • 16 citations

Antigen specific T cell factors

1980 • 16 citations

Effect of UV irradiation on expression of membrane IL 1 by rat macrophages.

1987 • 15 citations

Antigen-Binding T Cells: Dose Response and Kinetic Studies on the Development of Different Subsets

1979 • 15 citations

Immunoregulation of lysozyme‐specific suppression. II. Hen egg‐white lysozyme‐specific monoclonal suppressor T cell factor suppresses the afferent phase of delayed‐type hypersensitivity and induces second‐order suppressor T cells

1984 • 15 citations

Direct stimulation of T lymphocytes by antigen-conjugated beads.

1986 • 14 citations

Antigen-specific T cell receptors and factors

1987 • 14 citations

Partial purification and characterization of an antigen-specific helper factor synthesized by a T-cell continuous line.

1983 • 13 citations

Preparation of an antigen-binding fragment from murine T lymphocyte membranes

1980 • 11 citations

Induction of cytotoxic lymphocyte responses by antigen-specific helper factors.

1984 • 11 citations

Cellular interactions of L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)-specific suppressor factors. I. Inhibition of the activity of GAT-specific helper T cell clones by monoclonal GAT-specific suppressor T cell factors.

1986 • 10 citations

Information transfer between T cell subsets is directed by I-J+ antigen nonspecific molecules.

1985 • 10 citations

Isolation of antigen-binding membrane molecules from an antigen-specific T-cell hybrid

1986 • 9 citations

Production of an Antigen-Specific Component of Suppressor Inducer Factor by a Helper T-Cell Clone: Possible Role for IL-1 at the Interface of Immunity and Tolerance

1985 • 9 citations

The role of adherent accessory cells in the generation of effector suppressor T cells.

1986 • 8 citations

Immunosuppression by cell‐free translation products from monoclonal antigen‐specific suppressor T cell mRNA

1985 • 8 citations

A helper T cell clone produces an antigen-specific molecule (T-ABM) which functions in the induction of suppression.

1987 • 7 citations

Augmentation of the antibody response by antigen-specific glycosylation-enhancing factor.

1987 • 7 citations

Immunoregulatory pathways in adult responder mice. III. Establishment of a GAT-specific suppressor T cell clone from GAT-tolerant responders which afferently regulates DTH responses.

1985 • 6 citations

Composition of a Suppressor Factor That Inhibits the Immune Response to Lactate Dehydrogenase B

1984 • 6 citations

Identification and characterization of a suppressor T cell hybridoma specifically inducible by L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT).

1986 • 5 citations

Phenotypic similarity between T-cell antigen binding molecules.

1986 • 5 citations

ELISA Assay for the Detection of a Dextran‐Binding Product Secreted by a T‐Cell Hybrid Th 1

1987 • 4 citations

Antigen-specific non-immunoglobulin ‘antibody’-like molecules in rhesus monkey serum

1984 • 3 citations

Non-Proliferation Treaty Woes

1984 • 2 citations