GENERAL PROBLEMS OF DRUG ACTIONS ON BIOELECTRIC PHENOMENA

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Measurement of current‐voltage relations in the membrane of the giant axon of Loligo

1952 • 1,655 citations

An analysis of the end‐plate potential recorded with an intra‐cellular electrode

1951 • 1,389 citations

Cholinergic and inhibitory synapses in a pathway from motor‐axon collaterals to motoneurones

1954 • 1,172 citations

On some physiological actions of ergot

1906 • 980 citations

THE IONIC BASIS OF ELECTRICAL ACTIVITY IN NERVE AND MUSCLE

1951 • 959 citations

The local electric changes associated with repetitive action in a non‐medullated axon

1948 • 743 citations

The pharmacological basis of therapeutics

1955 • 718 citations

SINGLE- AND MULTIPLE-UNIT ANALYSIS OF CORTICAL STAGE OF PYRAMIDAL TRACT ACTIVATION

1954 • 683 citations

The specific ionic conductances and the ionic movements across the motoneuronal membrane that produce the inhibitory post‐synaptic potential

1955 • 568 citations

The recording of potentials from motoneurones with an intracellular electrode

1952 • 565 citations

On the localization of acetylcholine receptors

1955 • 522 citations

PROCESSES OF EXCITATION IN THE DENDRITES AND IN THE SOMA OF SINGLE ISOLATED SENSORY NERVE CELLS OF THE LOBSTER AND CRAYFISH

1955 • 446 citations

The Pharmacology of Vascular Smooth Muscle

1996 • 435 citations

The effect on the isolated rabbit heart of vagal stimulation and its modification by cocaine, hexamethonium and ouabain

1956 • 397 citations

Correlation between membrane potential, spike discharge and tension in smooth muscle

1955 • 361 citations

VAGAL AND SYMPATHETIC EFFECTS ON THE PACEMAKER FIBERS IN THE SINUS VENOSUS OF THE HEART

1956 • 359 citations

The spread of activity in the cerebral cortex

1936 • 338 citations

Properties of the ‘slow’ skeletal muscle fibres of the frog*

1953 • 317 citations

Interpretation of action potentials evoked in the cerebral cortex

1951 • 289 citations

SYNAPTIC INHIBITION IN AN ISOLATED NERVE CELL

1955 • 285 citations

The Mode of Neuromuscular Block Caused by Acetylcholine, Nicotine, Decamethonium and Suecinylcholine¹

1955 • 283 citations

Neural Control of the Pituitary Gland

1956 • 278 citations

CAUDAL AND CEPHALIC INFLUENCES OF THE BRAIN STEM RETICULAR FORMATION

1950 • 269 citations

Microelectrode studies of the electrical activity of the cerebral cortex in the cat*

1953 • 269 citations

Reactions of denervated voluntary muscle, and their bearing on the mode of action of parasympathetic and related nerves

1930 • 264 citations

The effect of inhibitory nerve impulses on a crustacean muscle fibre

1953 • 259 citations

Depolarization of the motor end‐plate by decamethonium and acetylcholine

1951 • 246 citations

Membrane potentials in the electroplates of the electric eel

1953 • 243 citations

Pharmacological investigations on a central synapse operated by acetylcholine

1956 • 239 citations

INTRACELLULAR RECORDS FROM BETZ CELLS IN THE CAT

1956 • 236 citations

NATURE OF THE "ENDPLATE POTENTIAL" IN CURARIZED MUSCLE

1941 • 231 citations

The relationship between depolarization and block in the cat's superior cervical ganglion

1953 • 230 citations

The Supersensitivity of Denervated Structures: A Law of Denervation

2013 • 223 citations

Local activity at a depolarized nerve-muscle junction

1955 • 211 citations

DENDRITIC POTENTIAL OF CORTICAL NEURONS PRODUCED BY DIRECT ELECTRICAL STIMULATION OF THE CEREBRAL CORTEX

1951 • 210 citations

THE PHARMACOLOGY OF FLAXEDIL, WITH OBSERVATIONS ON CERTAIN ANALOGS

1951 • 200 citations

Physiological and Pharmacological Observations on Muscle Receptor Organs of the Crayfish, Cambarus Clarkii Girard

1953 • 198 citations

NATURE OF DENDRITIC POTENTIALS AND SYNAPTIC MECHANISMS IN CEREBRAL CORTEX OF CAT

1956 • 189 citations

The membrane change produced by the neuromuscular transmitter

1954 • 181 citations

FURTHER STUDY OF SOMA, DENDRITE, AND AXON EXCITATION IN SINGLE NEURONS

1955 • 177 citations

Elektrobiologie

1912 • 168 citations

LAMINAR MICROELECTRODE STUDIES OF SPECIFIC SOMATOSENSORY CORTICAL POTENTIALS

1956 • 164 citations

The Electrophysiology of the Submaxillary Gland of the Cat.

1955 • 162 citations

Electrolytes in biological systems

1955 • 162 citations

Functional Organization of the Dorsal Spino-Cerebellar Tract in the Cat

1956 • 158 citations

Biophysics of Junctional Transmission

1954 • 158 citations

The actions of acetylcholine on denervated mammalian and frog's muscle

1937 • 153 citations

SPECIFIC EXCITABILITY OF THE ENDPLATE REGION IN NORMAL AND DENERVATED MUSCLE

1943 • 152 citations

CYTIDINE AND URIDINE REQUIREMENT OF THE BRAIN*†

1956 • 146 citations

Unitary activity of spinal interneurones of cats

1956 • 137 citations

Properties of dendrites; apical dendrites of the cat cortex

1955 • 133 citations

Production of Membrane Potential Changes in the Frog's Heart by Inhibitory Nerve Impulses

1955 • 132 citations

Intracellular potentials recorded from a mammalian sympathetic ganglion

1955 • 129 citations

LAMINAR MICROELECTRODE ANALYSIS OF CORTICAL UNSPECIFIC RECRUITING RESPONSES AND SPONTANEOUS RHYTHMS

1956 • 128 citations

CHEMICAL EXCITATION OF NERVE

1946 • 121 citations

The cholinergic nature of the nerves to the electric organ of the Torpedo (Torpedo marmorata)

1942 • 113 citations

ORIGIN, CONDUCTION AND TERMINATION OF IMPULSES IN THE DORSAL SPINO-CEREBELLAR TRACT OF CATS

1942 • 107 citations

The excitant action of acetylcholine and other substances on cutaneous sensory pathways and its prevention by hexamethonium and d‐tubocurarine

1953 • 100 citations

The mode of action of drugs on cells

1933 • 94 citations

CORTICAL MOTOR THRESHOLD AND THE THRESHOLDS AND DISTRIBUTION OF EXCITED BETZ CELLS IN THE CAT

1956 • 90 citations

The Transmission of Nerve Impulses at Neuroeffector Junctions and Peripheral Synapses

1951 • 89 citations

Synaptic potentials and transmission in sympathetic ganglion

1943 • 89 citations

The action of the neuromuscular transmitter on the slow fibre membrane

1956 • 81 citations

Elektrophysiologie

1895 • 80 citations

Recherches Sur La Physiologie Et La Pharmacologie Du Système Nerveux Autonome

1936 • 75 citations

Nature of neuromuscular facilitation by sympathetic stimulation in the frog

1955 • 71 citations

Rhythmic activity in skeletal muscle fibres

1933 • 71 citations

INITIATION AND ABOLITION OF THE ACTION POTENTIAL OF A SINGLE NODE OF RANVIER

1956 • 67 citations

SIMILARITY IN ACTION BETWEEN CURARE AND STRYCHNINE ON CORTICAL NEURONS

1953 • 66 citations

ADRENERGIC INHIBITION AT SYMPATHETIC SYNAPSES

1939 • 65 citations

AN ELECTRICAL HYPOTHESIS OF SYNAPTIC AND NEURO‐MUSCULAR TRANSMISSION

1946 • 64 citations

Ion Transport Across Biological Membranes

1954 • 63 citations

The quantum efficiency of bleaching of rhodopsin in situ.

1955 • 60 citations

Über den direkt und indirekt erregten Aktionsstrom und die Funktion der motorischen Endplatte

1938 • 59 citations

ASCENDING FIBERS IN PYRAMIDAL TRACT OF CAT

1952 • 59 citations

ACTIVE TRANSPORT AND SECRETION

1955 • 59 citations

MECHANISMS OF DIRECT AND NEURAL EXCITABILITY IN ELECTROPLAQUES OF ELECTRIC EEL

1955 • 58 citations

THE ELECTRICAL ACTIVITIES OF SINGLE MOTONEURONES IN TOAD'S SPINAL CORD, RECORDED WITH INTRACELLULAR ELECTRODES

1952 • 57 citations

Rapport N° 1 Aspects Anatomiques de la Transmission Synaptique Ganglionnaire chez les Mammifères

1951 • 54 citations

The facilitatory effect of stimulation of an unspecific thalamic nucleus on cortical sensory neuronal responses

1956 • 52 citations

The electrical activity of the cerebellum and its functional significance

1938 • 52 citations

MECHANISMS OF BIOELECTRIC ACTIVITY IN ELECTRIC TISSUE

1953 • 51 citations

The Electrical and Mechanical Events of Neuro-Muscular Transmission in the Cockroach, Periplaneta Americana (L.)*

1950 • 50 citations

The excitable substances of amphibian muscle

1907 • 50 citations

Gesammelte Abhandlungen zur allgemeinen Muskel- und Nervenphysik Band 2

1877 • 48 citations

Correlation between steady transcortical potential and evoked response

1954 • 48 citations

The beginnings and the prospects of neurohumoral transmission.

1954 • 44 citations

EXPERIMENTAL ANALYSIS OF THE INHIBITORY ACTION OF LYSERGIC ACID DIETHYLAMIDE ON CORTICAL DENDRITIC ACTIVITY

1957 • 42 citations

Noradrenaline.

1956 • 41 citations

A reversed action of the vagus on the mammalian heart

1910 • 40 citations

The role of acetylcholine in synaptic transmission at parasympathetic ganglia

1953 • 40 citations

ACTION POTENTIAL OF INSECT MUSCLE EXAMINED WITH INTRA-CELLULAR ELECTRODE

1954 • 39 citations

A Link between ‘Models’ and Living Muscle

1954 • 38 citations

Reactions of avian muscle to acetylcholine and eserine

1938 • 37 citations

THE PHARMACOLOGY OF DECAMETHONIUM

1951 • 36 citations

Excitability of the single fibre nerve‐muscle complex

1932 • 35 citations

Central and sensory transmission.

1954 • 35 citations

Effects of close arterial injections of acetylcholine on the activity of the cervical spinal cord of the cat

1953 • 30 citations

ELECTRIC EXCITABILITY OF NERVE-MUSCLE FIBRE PREPARATIONS

1945 • 30 citations

Pharmacology of the neuromuscular junction.

1950 • 29 citations

Electrical activity in electric tissue III. Modifications of electrical activity by acetylcholine and related compounds

1955 • 29 citations

CURARIZATION OF DENERVATED MUSCLE

1951 • 29 citations

INFLUENCE OF ESTRONE ON THE ELECTRIC CHARACTERISTICS AND THE MOTILITY OF UTERINE MUSCLE

1941 • 28 citations

SYNTHETIC DRUGS INFLUENCING NEUROMUSCULAR ACTIVITY

1951 • 28 citations

ADRENERGIC MECHANISM OF VAGAL CARDIOSTIMULATION

1949 • 28 citations

Adaptation to constant concentrations of acetylcholine.

1956 • 27 citations

EFFECT OF CURARE ON CORTICAL RESPONSES EVOKED BY AFFERENT STIMULATION

1949 • 25 citations

THE ROLE OF HUMORAL AGENTS IN NERVOUS ACTIVITY

1955 • 23 citations

Physiology of Neuromuscular Transmission and Neuromuscular Block

1951 • 22 citations

Action and resting potentials of cortical neurones

1955 • 22 citations

Electrochemistry in Biology and Medicine.

1955 • 20 citations

Central and Synaptic Transmission (Pharmacological Aspects)

1956 • 20 citations

The interruption of neuromuscular transmission and some of its problems.

1954 • 18 citations

Croonian lecture.—On the origin and the causation of vital movement ( ueber die entstehung der vitalen bewegung )

1888 • 17 citations

Blockade of Cardiac Synapses by Succinylcholine

1956 • 16 citations

ON THE PREGNANCY-RESPONSE OF THE UTERUS OF THE CAT

1929 • 14 citations

Neural Transmission in Invertebrates

1953 • 13 citations

THE REVERSAL BY PROGESTIN OF RESPONSES OF THE NONPREGNANT UTERUS OF THE CAT

1936 • 13 citations

Studies on certain sensory and motor systems of decapod crustaceans

1955 • 12 citations

The discharge of individual electroplates in Raia clavata.

1953 • 12 citations

The Difference in Response of Monosynaptic Extensor and Monosynaptic Flexor Reflexes to d‐Tubocurarine and Adrenaline

1953 • 11 citations

CHELATING AGENTS IN THE STUDY OF RENAL ABSORPTION OF ALKALINE EARTH CATIONS

1956 • 11 citations

Slow and Fast Responses in Cockroach Leg Muscle

1954 • 11 citations

Physiology of neuro-muscular junctions.

1948 • 10 citations

PHYSICAL AND CHEMICAL ASPECTS OF NEUROMUSCULAR TRANSMISSION

1936 • 10 citations

Neurological Anatomy in Relation to Clinical Medicine

1949 • 8 citations

Electroencephalographic patterns following intraventricular injection of tubocurarine in the cat.

1955 • 8 citations

Two types of inhibition of cerebellar Purkinje cells.

1956 • 7 citations

Three excitable systems of the synaptic unit in the innervated electroplaque preparation.

1954 • 7 citations

Inexcitability of Cortical Dendrites to Electric Stimuli

1956 • 6 citations

Diversity of transmission processes as exemplified by specific synapses in electric organs

1952 • 5 citations

Excitatory and inhibitory effects of the chemical mediators

1950 • 3 citations