Factors Affecting Inverted Repeat Stimulation of Recombination and Deletion in Saccharomyces cerevisiae

[12] One-step gene disruption in yeast

1983 • 3,302 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

NONVIRAL RETROPOSONS: GENES, PSEUDOGENES, AND TRANSPOSABLE ELEMENTS GENERATED BY THE REVERSE FLOW OF GENETIC INFORMATION

1986 • 1,032 citations

On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletions

1982 • 690 citations

Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources.

1989 • 578 citations

A family of low and high copy replicative, integrative and single‐stranded S. cerevisiae/E. coli shuttle vectors

1991 • 533 citations

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

1985 • 453 citations

DNA double-strand breaks caused by replication arrest

1997 • 428 citations

A ubiquitous family of repeated DNA sequences in the human genome

1979 • 420 citations

Collapse and repair of replication forks in Escherichia coli

1995 • 374 citations

MEIOTIC RECOMBINATION HOTSPOTS

1995 • 362 citations

The nucleotide sequence of the ubiquitous repetitive DNA sequence B1 complementary to the most abundant class of mouse fold-back RNA

1980 • 326 citations

Molecular Basis of Genetic Instability of Triplet Repeats

1996 • 310 citations

Trinucleotide repeats associated with human disease

1997 • 288 citations

Repair of Site-Specific Double-Strand Breaks in a Mammalian Chromosome by Homologous and Illegitimate Recombination

1997 • 270 citations

A position effect on the time of replication origin activation in yeast

1992 • 263 citations

Holliday Junctions Accumulate in Replication Mutants via a RecA Homolog-Independent Mechanism

1997 • 262 citations

Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair

1994 • 259 citations

Structural intermediates of deletion mutagenesis: a role for palindromic DNA.

1984 • 251 citations

DNA synthesis dependent on genetic recombination: Characterization of a reaction catalyzed by purified bacteriophage T4 proteins

1986 • 250 citations

Palindromes in chromosomes

1974 • 247 citations

Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E. coli

1991 • 230 citations

Alu-Alu recombination deletes splice acceptor sites and produces secreted low density lipoprotein receptor in a subject with familial hypercholesterolemia.

1987 • 228 citations

The ADE2 gene from Saccharomyces cerevisiae: sequence and new vectors

1990 • 221 citations

Genome instability in a region of human DNA enriched in Alu repeat sequences

1982 • 220 citations

Stability of a CTG/CAG Trinucleotide Repeat in Yeast Is Dependent on Its Orientation in the Genome

1997 • 217 citations

Deletion mutations affecting autonomously replicating sequence ARS1 of Saccharomyces cerevisiae.

1984 • 210 citations

Three Tn10-associated excision events: Relationship to transposition and role of direct and inverted repeats

1981 • 204 citations

DNA replication in eukaryotic cells

1997 • 194 citations

In vivo biochemistry: Physical monitoring of recombination induced by site‐specific endonucleases

1995 • 191 citations

Human Chromosomal Fragile Site FRA16B Is an Amplified AT-Rich Minisatellite Repeat

1997 • 182 citations

Inverted DNA Repeats: a Source of Eukaryotic Genomic Instability

1993 • 180 citations

Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemia.

1986 • 168 citations

Substrate Length Requirements for Efficient Mitotic Recombination in Saccharomyces cerevisiae

1993 • 163 citations

Palindrome Resolution and Recombination in the Mammalian Germ Line

1997 • 160 citations

Occurrence of potential cruciform and H-DNA forming sequences in genomic DNA

1995 • 159 citations

The Expanding World of Trinucleotide Repeats

1996 • 157 citations

Single-stranded hexameric linkers: a system for in-phase insertion mutagenesis and protein engineering

1985 • 151 citations

Two types of replication proteins increase the rate at which T4 DNA polymerase traverses the helical regions in a single-stranded DNA template.

1981 • 147 citations

Excision of transposon Tn5 is dependent on the inverted repeats but not on the transposase function of Tn5.

1981 • 124 citations

Instability of Palindromic DNA in Escherichia coli

1981 • 120 citations

An electron microscope study of the DNA sequence organization of the human genome

1976 • 117 citations

Precise and nearly-precise excision of the symmetrical inverted repeats of Tn 5; common features of recA-independent deletion events in Escherichia coli

1982 • 116 citations

When replication forks stop

1994 • 115 citations

Replication Slippage between Distant Short Repeats in Saccharomyces cerevisiae Depends on the Direction of Replication and the RAD50 and RAD52 Genes

1995 • 114 citations

On the deletion of inverted repeated DNA in Escherichia coli: effects of length, thermal stability, and cruciform formation in vivo.

1991 • 114 citations

Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III

1983 • 111 citations

Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae.

1993 • 106 citations

DNA rearrangement mediated by inverted repeats.

1996 • 105 citations

Initiation at Closely Spaced Replication Origins in a Yeast Chromosome

1993 • 104 citations

Torsionally tuned cruciform and Z-DNA probes for measuring unrestrained supercoiling at specific sites in DNA of living cells

1991 • 92 citations

Instability of long inverted repeats within mouse transgenes.

1996 • 92 citations

Structural plasmid instability in Bacillus subtilis: Effect of direct and inverted repeats

1988 • 89 citations

Template-directed pausing in in vitro DNA synthesis by DNA polymerase a from Drosophila melanogaster embryos.

1982 • 87 citations

A 140-bp-Long Palindromic Sequence Induces Double-Strand Breaks During Meiosis in the Yeast Saccharomyces cerevisiae

1997 • 87 citations

Primate origin of the CMT1A-REP repeat and analysis of a putative transposon-associated recombinational hotspot

1996 • 85 citations

Local DNA Sequence Control of Deletion Formation in Escherichia coli Plasmid pBR322

1987 • 84 citations

Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes.

1992 • 77 citations

Insertion, Excision, and Inversion of Tn5

1981 • 73 citations

An electron microscopic study of mouse foldback DNA

1975 • 72 citations

Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli.

1996 • 67 citations

Gene conversions and crossing over during homologous and homeologous ectopic recombination in Saccharomyces cerevisiae.

1993 • 64 citations

Differential DNA secondary structure-mediated deletion mutation in the leading and lagging strands

1995 • 64 citations

Nearly precise excision: a new type of DNA alteration associated with the translocatable element Tn10

1979 • 62 citations

Recombination between short repeated sequences is more frequent in plasmids than in the chromosome of Bacillus subtilis

1987 • 58 citations

Cellular DNA Polymerases

1996 • 57 citations

Illegitimate Recombination in Bacteria

2014 • 54 citations

Transposition of a DNA sequence determining kanamycin resistance into the single-stranded genome of bacteriophage fd

1978 • 54 citations

Copy-choice illegitimate DNA recombination revisited.

1994 • 52 citations

Repetitive Elements form a Cruciform Structure that Regulates the Function of the Human CD8α T Cell-specific En hancer

1995 • 52 citations

Palindromy and the location of deletion endpoints in Escherichia coli.

1989 • 50 citations

Pauses at positions of secondary structure during in vitro replication of single-stranded fd Bacteriophage DNA by T4 DNA polymerase

1980 • 49 citations

Mutations in POL1 increase the mitotic instability of tandem inverted repeats in Saccharomyces cerevisiae.

1993 • 46 citations

Effect of base composition at the center of inverted repeated DNA sequences on cruciform transitions in DNA.

1988 • 44 citations

Structure and Expression of the Gene Encoding Secretor‐Type Galactoside 2‐α‐<scp>l</scp>‐fucosyltransferase (FUT2)

1997 • 43 citations

Genomic organization of the human PAX3 gene: DNA sequence analysis of the region disrupted in alveolar rhabdomyosarcoma

1995 • 39 citations

Instability of a plasmid-borne inverted repeat in Saccharomyces cerevisiae.

1993 • 36 citations

Altered Replication and Inverted Repeats Induce Mismatch Repair-Independent Recombination between Highly Diverged DNAs in Yeast

1997 • 34 citations

Mechanism of F factor-enhanced excision of transposon Tn5

1983 • 34 citations

Stimulation of precise excision and recombination by conjugal proficient F′ plasmids

1986 • 31 citations

A cruciform-dumbbell model for inverted dimer formation mediated by inverted repeats

1997 • 26 citations

Deletion of the C-terminal end of aspartylgiucosaminidase resulting in a lysosomal accumulation disease: evidence for a unique genomic rearrangement

1995 • 26 citations

The Organization of the Gene (EPB72) Encoding the Human Erythrocyte Band 7 Integral Membrane Protein (Protein 7.2b)

1995 • 23 citations

Effects of palindrome size and sequence on genetic stability in the bacteriophage φX174 genome

1987 • 21 citations

Yeast mutants with increased bacterial transposon Tn5 excision

1991 • 20 citations

Precise excision of bacterial transposon Tn 5 in yeast

1988 • 17 citations

Characterization of foldback sequences in hamster DNA using electron microscopy

1977 • 16 citations

DIR: a novel DNA rearrangement associated with inverted repeats

1997 • 13 citations

Structure and distribution of inverted repeats (palindromes)

1981 • 12 citations

The effects of central asymmetry on the propagation of palindromic DNA in bacteriophage lambda are consistent with cruciform extrusion in vivo.

1993 • 12 citations

Organisation of inverted repeat sequences in hamster cell nuclear DNA

1979 • 10 citations

Structure and distribution of inverted repeats (palindromes)

1981 • 10 citations

Localisation of foldback DNA sequences in nuclei and chromosomes of Scilla, Secale, and of mouse

1978 • 8 citations

The human mdr1 (multidrug-resistance) gene harbours a long homopyrimidine·homopurine sequence next to a cluster of Alu repeated sequences in intron 14

1995 • 8 citations

[Development of a system of intragenic mapping for molecular genetic analysis of mutations in the gene LYS2 of Saccharomyces yeasts].

1990 • 6 citations

Analysis of Inverted Repeat DNA in the Genome of Rhodomicrobium vannielii

1986 • 6 citations

[The recombination mechanism for precise excision of the IS50 mobile element in Escherichia coli K12 cells].

1994 • 3 citations

[The kidney in shock. A new experimental method for the induction of controlled shock. I].

1981 • 1 citations