Light-Induced Conformational Changes of Rhodopsin Probed by Fluorescent Alexa594 Immobilized on the Cytoplasmic Surface

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

2000 • 5,539 citations

Molecular Basis of Visual Excitation

1968 • 1,002 citations

Cyanine dye labeling reagents: Sulfoindocyanine succinimidyl esters

1993 • 851 citations

Alexa Dyes, a Series of New Fluorescent Dyes that Yield Exceptionally Bright, Photostable Conjugates

1999 • 836 citations

Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin.

1989 • 663 citations

Tautomeric Forms of Metarhodopsin

1963 • 602 citations

Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes

1980 • 561 citations

Pre-Lumirhodopsin and the Bleaching of Visual Pigments

1963 • 520 citations

The structure of bovine rhodopsin

1983 • 513 citations

Effect of Carboxylic Acid Side Chains on the Absorption Maximum of Visual Pigments

1989 • 469 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

Two adjacent cysteine residues in the C‐terminal cytoplasmic fragment of bovine rhodopsin are palmitylated

1988 • 409 citations

Three cytoplasmic loops of rhodopsin interact with transducin.

1989 • 370 citations

Light‐induced binding of 48‐kDa protein to photoreceptor membranes is highly enhanced by phosphorylation of rhodopsin

1984 • 358 citations

Site of Attachment of Retinal in Rhodopsin

1967 • 352 citations

Light-regulated binding of rhodopsin kinase and other proteins to cattle photoreceptor membranes

1978 • 313 citations

Mechanism of rhodopsin kinase activation

1991 • 301 citations

Micropatterned immobilization of a G protein–coupled receptor and direct detection of G protein activation

1999 • 276 citations

Texas red, a hydrophilic, red-emitting flourophore for use with flourescein in dual parameter flow microfluorometric and fluorescence microscopic studies

1982 • 270 citations

Complex formation between metarhodopsin II and GTP‐binding protein in bovine protoreceptor membranes leads to a shift of the photoproduct equilibrium

1982 • 259 citations

Visual pigment: G-protein-coupled receptor for light signals

1998 • 243 citations

Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.

1993 • 235 citations

Progress in retinal research

1982 • 213 citations

THE ROLE OF SULFHYDRYL GROUPS IN THE BLEACHING AND SYNTHESIS OF RHODOPSIN

1952 • 211 citations

Kinetics, binding constant, and activation energy of the 48-kDa protein-rhodopsin complex by extra-metarhodopsin II

1989 • 193 citations

Mapping Light-Dependent Structural Changes in the Cytoplasmic Loop Connecting Helixes C and D in Rhodopsin: A Site-Directed Spin Labeling Study

1995 • 160 citations

Mutation of the Fourth Cytoplasmic Loop of Rhodopsin Affects Binding of Transducin and Peptides Derived from the Carboxyl-terminal Sequences of Transducin α and γ Subunits

2000 • 159 citations

The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction

1992 • 151 citations

Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state.

1993 • 148 citations

Resonance Raman studies of bovine metarhodopsin I and metarhodopsin II

1978 • 146 citations

Plasmon resonance spectroscopy: probing molecular interactions within membranes

1999 • 144 citations

Light-Induced Interaction between Rhodopsin and the GTP-Binding Protein. Metarhodopsin II Is the Major Photoproduct Involved

1982 • 142 citations

Palmitylation of a G-protein coupled receptor. Direct analysis by tandem mass spectrometry.

1992 • 134 citations

Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin

1993 • 120 citations

Signaling States of Rhodopsin

2000 • 92 citations

Structure and function in rhodopsin: Rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state

1997 • 89 citations

Structure and Function in Rhodopsin. Cysteines 65 and 316 Are in Proximity in a Rhodopsin Mutant As Indicated by Disulfide Formation and Interactions between Attached Spin Labels

1996 • 87 citations

Phosphorylation Modulates the Affinity of Light-Activated Rhodopsin for G Protein and Arrestin

2000 • 76 citations

Shift in the relation between flash‐induced metarhodopsin I and metarhodopsin II within the first 10% rhodopsin bleaching in bovine disc membranes

1981 • 70 citations

Binding of inositol phosphates to arrestin

1991 • 67 citations

Structure and Function in Rhodopsin: Effects of Disulfide Cross-Links in the Cytoplasmic Face of Rhodopsin on Transducin Activation and Phosphorylation by Rhodopsin Kinase^,

1999 • 64 citations

Photochemical and Biochemical Properties of Chicken Blue-Sensitive Cone Visual Pigment

1997 • 58 citations

Effects of Carboxy-Terminal Truncation on the Stability and G Protein-Coupling Activity of Bovine Rhodopsin

1994 • 56 citations

Comparative study on the chromophore binding sites of rod and red-sensitive cone visual pigments by use of synthetic retinal isomers and analogs

1990 • 53 citations

Difference in Molecular Properties between Chicken Green and Rhodopsin as Related to the Functional Difference between Cone and Rod Photoreceptor Cells

1995 • 51 citations

Interplay between hydroxylamine, metarhodopsin II and GTP-binding protein in bovine photoreceptor membranes

1983 • 50 citations

Binding of Arrestin to Cytoplasmic Loop Mutants of Bovine Rhodopsin

1999 • 44 citations

Circular Dichroism of Metaiodopsin II and Its Binding to Transducin: A Comparative Study between Meta II Intermediates of Iodopsin and Rhodopsin

1994 • 43 citations

[32] Intrinsic biophysical monitors of transducin activation: Fluorescence, UV-visible spectroscopy, light scattering, and evanescent field techniques

2000 • 43 citations

State-Dependent Disulfide Cross-Linking in Rhodopsin

1999 • 42 citations

Evidence for differently protonated forms of metarhodopsin II as intermediates in the decay of membrane-bound cattle rhodopsin

1978 • 37 citations

The structure of mammalian rod opsins

1984 • 37 citations

Structure and function in rhodopsin: covalent crosslinking of the rhodopsin (metarhodopsin II)-transducin complex--the rhodopsin cytoplasmic face links to the transducin alpha subunit.

1994 • 29 citations

Direct observation of the thermal equilibria among lumirhodopsin, metarhodopsin I, and metarhodopsin II in chicken rhodopsin

1994 • 28 citations

Intrahelical Arrangement in the Integral Membrane Protein Rhodopsin Investigated by Site-Specific Chemical Cleavage and Mass Spectrometry

2000 • 27 citations

The carboxyl terminus of bovine rhodopsin is not required for G protein activation.

1994 • 25 citations

Temperature and pH Dependence of the Metarhodopsin I−Metarhodopsin II Equilibrium and the Binding of Metarhodopsin II to G Protein in Rod Disk Membranes

1999 • 15 citations