Human Dendritic Cells Produce TGF-β1 under the Influence of Lung Carcinoma Cells and Prime the Differentiation of CD4+CD25+Foxp3+ Regulatory T Cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

2002 • 5,109 citations

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 • 4,529 citations

Tumour-educated macrophages promote tumour progression and metastasis

2004 • 3,259 citations

Tolerogenic Dendritic Cells

2003 • 3,131 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Paradoxical roles of the immune system during cancer development

2006 • 2,213 citations

TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES

2005 • 2,075 citations

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Regulatory T cells, tumour immunity and immunotherapy

2006 • 2,009 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

The lineage decisions of helper T cells

2002 • 1,678 citations

Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer

2001 • 1,309 citations

Dendritic cells as therapeutic vaccines against cancer

2005 • 1,195 citations

Dendritic cells in a mature age

2006 • 1,147 citations

Mechanisms and functional significance of tumour-induced dendritic-cell defects

2004 • 995 citations

Regulation of T Cell Immunity by Dendritic Cells

2001 • 984 citations

Cross-Presentation, Dendritic Cells, Tolerance and Immunity

2001 • 894 citations

The IL-12 Family of Heterodimeric Cytokines

2003 • 889 citations

IL-6 switches the differentiation of monocytes from dendritic cells to macrophages

2000 • 879 citations

Dynamics of T Lymphocyte Responses: Intermediates, Effectors, and Memory Cells

2000 • 807 citations

Regulatory T cells in cancer

2006 • 717 citations

Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4+CD25+ regulatory T cell proliferation

2005 • 716 citations

Cutting Edge: Regulatory T Cells from Lung Cancer Patients Directly Inhibit Autologous T Cell Proliferation

2002 • 713 citations

Clinical significance of defective dendritic cell differentiation in cancer.

2000 • 694 citations

Mechanism of Transforming Growth Factor β–induced Inhibition of T Helper Type 1 Differentiation

2002 • 501 citations

Release of High Mobility Group Box 1 by Dendritic Cells Controls T Cell Activation via the Receptor for Advanced Glycation End Products

2005 • 498 citations

Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells

2004 • 482 citations

Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion.

1996 • 330 citations

The B7 Family and Cancer Therapy: Costimulation and Coinhibition

2007 • 326 citations

Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients

2006 • 302 citations

De novogeneration of antigen-specific CD4⁺CD25⁺regulatory T cells from human CD4⁺CD25^–cells

2005 • 284 citations

Immunoregulatory T cells in tumor immunity

2004 • 257 citations

Regulatory T cells and treatment of cancer

2008 • 253 citations

Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor

2003 • 241 citations

Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.

2003 • 229 citations

Dendritic cells with TGF-β1 differentiate naïve CD4⁺CD25⁻T cells into islet-protective Foxp3⁺regulatory T cells

2007 • 229 citations

CD28 ligation in T-cell activation: evidence for two signal transduction pathways

1990 • 173 citations

Prognostic molecular markers in non-small cell lung cancer

2001 • 94 citations

Brefeldin A, but not monensin, completely blocks CD69 expression on mouse lymphocytes:

1999 • 90 citations

Cutting Edge: Immature Human Dendritic Cells Express Latency-Associated Peptide and Inhibit T Cell Activation in a TGF-β-Dependent Manner

2007 • 86 citations

CD28 ligation in T-cell activation: evidence for two signal transduction pathways

1990 • 21 citations