Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

Angiogenesis in life, disease and medicine

2005 • 3,331 citations

Role of angiogenesis in tumor growth and metastasis

2002 • 2,412 citations

Role of angiogenesis in tumor growth and metastasis

2002 • 2,310 citations

IDENTIFICATION OF POLYMORPHISMS WITHIN THE VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) GENE: CORRELATION WITH VARIATION IN VEGF PROTEIN PRODUCTION

2000 • 731 citations

Barrett's Esophagus

2002 • 588 citations

A Common Polymorphism in the 5′-Untranslated Region of the VEGF Gene Is Associated With Diabetic Retinopathy in Type 2 Diabetes

2002 • 554 citations

A Common 936 C/T Mutation in the Gene for Vascular Endothelial Growth Factor Is Associated with Vascular Endothelial Growth Factor Plasma Levels

2000 • 545 citations

Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter.

2003 • 370 citations

A common 936 C/T gene polymorphism of vascular endothelial growth factor is associated with decreased breast cancer risk

2003 • 322 citations

Barrett's metaplasia

2000 • 321 citations

Epidemiology of esophageal adenocarcinoma

2005 • 294 citations

Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor121.

1995 • 257 citations

Association of the VEGF Gene With Proliferative Diabetic Retinopathy But Not Proteinuria in Diabetes

2004 • 199 citations

Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma

2002 • 162 citations

Nicotine and Cotinine Up-Regulate Vascular Endothelial Growth Factor Expression in Endothelial Cells

2002 • 155 citations

Nicotine Promotes Colon Tumor Growth and Angiogenesis through -Adrenergic Activation

2007 • 152 citations

Association of Genetic Polymorphisms in the VEGF Gene with Breast Cancer Survival

2005 • 151 citations

Accounting for haplotype uncertainty in matched association studies: A comparison of simple and flexible techniques

2005 • 139 citations

Vascular Endothelial Growth Factor Gene Polymorphisms and Risk of Primary Lung Cancer

2005 • 136 citations

Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes

2005 • 134 citations

Vascular endothelial growth factor in esophageal cancer

2004 • 134 citations

Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2

2004 • 124 citations

Vascular endothelial growth factor gene−460 C/T polymorphism is a biomarker for prostate cancer

2003 • 114 citations

Incipient Angiogenesis in Barrett’s Epithelium and Lymphangiogenesis in Barrett’s Adenocarcinoma

2002 • 108 citations

Vascular endothelial growth factor polymorphisms in gastric cancer development, prognosis, and survival

2006 • 106 citations

Population-Based Case-Control Study of VEGF Gene Polymorphisms and Breast Cancer Risk among Chinese Women

2006 • 98 citations

Angiogenesis in the neoplastic sequence of Barrett's oesophagus. Correlation with VEGF expression

2000 • 98 citations

VEGFR‐2 inhibition augments cigarette smoke‐induced oxidative stress and inflammatory responses leading to endothelial dysfunction

2008 • 88 citations

Vascular endothelial growth factor and basic fibroblast growth factor expression in esophageal adenocarcinoma and Barrett esophagus

2003 • 85 citations

Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in esophageal adenocarcinoma

2005 • 84 citations

Influence of VEGF‐A gene variation and protein levels in breast cancer susceptibility and severity

2007 • 77 citations

Vascular endothelial growth factor gene polymorphisms associated with prognosis for patients with gastric cancer

2007 • 75 citations

Vascular Endothelial Growth Factor Genotypes, Haplotypes, Gender, and the Risk of Non–Small Cell Lung Cancer

2008 • 68 citations

Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for oral cancer

2005 • 64 citations

A mechanistic study of colon cancer growth promoted by cigarette smoke extract

2005 • 61 citations

Nicotine-induced vascular endothelial growth factor release via the EGFR-ERK pathway in rat vascular smooth muscle cells

2007 • 58 citations

The ‘angiogenic switch’ in the progression from Barrett's metaplasia to esophageal adenocarcinoma

2003 • 54 citations

Prognostic significance and effect of chemoradiotherapy on microvessel density (angiogenesis) in esophageal Barrett's esophagus-associated adenocarcinoma and squamous cell carcinoma

1999 • 51 citations

Single Nucleotide Polymorphisms in the 3' Untranslated Region of Vascular Endothelial Growth Factor Gene in Japanese Population with or without Renal Cell Carcinoma.

2002 • 48 citations

An Anti-Human VEGF Monoclonal Antibody, MV833, That Exhibits Potent Anti-Tumor ActivityIn Vivo

1998 • 42 citations

Vascular endothelial growth factor (VEGF) gene (VEGFA) polymorphism can predict the prognosis in acute myeloid leukaemia patients

2007 • 37 citations

Clinical implication of vascular endothelial growth factor T-460C polymorphism in the risk and progression of prostate cancer

2007 • 33 citations

Vascular Endothelial Growth Factor Expression and Neovascularization in Barrett’s Carcinoma

2004 • 22 citations

Angiogenesis and neoplastic transformation of Barrett's epithelium

2004 • 4 citations