Occurrence of components of fibrinolysis pathways in situ in neoplastic and nonneoplastic human breast tissue.

[Cancer of the breast].

1962 • 940 citations

The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type.

1986 • 466 citations

Mammary plasminogen activator: correlation with involution, hormonal modulation and comparison between normal and neoplastic tissue

1979 • 437 citations

The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining.

1986 • 347 citations

A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification.

1988 • 275 citations

Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.

1984 • 274 citations

Characterization of the Cellular Binding Site for the Urokinase-type Plasminogen Activator

1989 • 248 citations

Transfection of v- ras ^H DNA into MCF-7 Human Breast Cancer Cells Bypasses Dependence on Estrogen for Tumorigenicity

1985 • 185 citations

A sensitive assay for tissue plasminogen activator

1982 • 182 citations

ras p21 Expression in the progression of breast cancer

1987 • 172 citations

Specificity of a monoclonal antibody for the NH2-terminal region of fibrin

1984 • 141 citations

Proliferation of a human epidermal tumor cell line stimulated by urokinase

1987 • 132 citations

Prognostic significance of the expression of a ras protein with a molecular weight of 21,000 by human breast cancer.

1987 • 130 citations

Urokinase-related proteins in human urine. Isolation and characterization of single-chain urokinase (pro-urokinase) and urokinase-inhibitor complex.

1986 • 126 citations

Cellular Localisation in Placenta of Placental Type Plasminogen Activator Inhibitor

1986 • 126 citations

Plasminogen activator activity and composition in human breast cancer.

1982 • 123 citations

Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator.

1986 • 114 citations

The Role of Hemostasis and Fibrinolysis in the Metastatic Spread of Cancer

1984 • 105 citations

Tissue-type plasminogen activator, a new prognostic marker in breast cancer.

1988 • 88 citations

Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). Modulation by glucocorticoids.

1986 • 82 citations

Papers presented at the Eighth Annual Cancer Symposium of the James Ewing Society. Fibrinolytic activity of human tumors as measured by the Fibrin-plate method

1955 • 73 citations

Characterization of plasminogen activators from normal human breast and colon and from breast and colon carcinomas

1984 • 72 citations

Fibrinogen deposition without thrombin generation in primary human breast cancer tissue.

1991 • 72 citations

Do proteases play a role in cancer invasion and metastasis?

1987 • 65 citations

A monoclonal antibody with ability to distinguish between NH2-terminal fragments derived from fibrinogen and fibrin

1983 • 59 citations

Proteolytic Enzymes in Tumor Invasion and Degradation of Host Extracellular Matrices

1986 • 42 citations

Fibrinolysis in human malignant tumours.

1973 • 40 citations

The plasmin system in human adenocarcinomas and their metastases. A comparative immunofluorescence study

1987 • 39 citations

ras, c-myc and c-erbB-2 oncoproteins in human breast cancer.

1989 • 37 citations

Immunohistochemical characterization of fibrin(ogen)-related antigens in human tissues using monoclonal antibodies.

1989 • 37 citations

Relationship of membrane-bound tissue type and urokinase type plasminogen activators in human breast cancers to estrogen and epidermal growth factor receptors.

1988 • 34 citations

Modulation of Plasminogen Activator Systems by Matrix Components in Two Breast Cancer Cell Lines: MCF-7 and MDA-MB-231

1989 • 28 citations

Hormonal modulation of plasminogen activator: an approach to prediction of human breast tumor responsiveness.

1987 • 27 citations

Induction of urokinase activity and malignant phenotype in bladder carcinoma cells after transfection of the activated Ha-ras oncogene

1989 • 26 citations

Hemostatic alterations are unrelated to the stage of tumor in untreated malignant melanoma and breast carcinoma

1985 • 25 citations

Urokinase‐type plasminogen activator biosynthesis is induced by the EJ‐Ha‐ras oncogene in CL26 mouse colon carcinoma cells

1989 • 24 citations

Plasminogen activators in human breast cancer cell lines: Hormonal regulation and properties

1988 • 16 citations

Plasminogen activator expression and steroid hormone receptors in female breast cancer: A multifactorial study

1988 • 13 citations

In Vivo Measurements of Fibrin Formation and Fibrinolysis in Operable Breast Cancer

1989 • 11 citations

Fibrinolytic Activity in Human Tumor Tissues

1983 • 11 citations

Urokinase and tissue-type plasminogen activators are present in breast cyst fluids

1988 • 3 citations