Local recurrences and distant metastases after breast-conserving surgery and radiation therapy for early breast cancer

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

TNM Classification of Malignant Tumours

1987 • 16,209 citations

Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel-Haenszel Procedure

1963 • 2,648 citations

Five-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Segmental Mastectomy with or without Radiation in the Treatment of Breast Cancer

1985 • 2,186 citations

Eight-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Lumpectomy with or without Irradiation in the Treatment of Breast Cancer

1989 • 1,604 citations

Reanalysis and Results after 12 Years of Follow-up in a Randomized Clinical Trial Comparing Total Mastectomy with Lumpectomy with or without Irradiation in the Treatment of Breast Cancer

1995 • 1,480 citations

A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive Tumors

1989 • 1,471 citations

Histologic multifocality of tis, T1–2 breast carcinomas implications for clinical trials of breast-conserving surgery

1985 • 1,133 citations

Ten-Year Results of a Comparison of Conservation with Mastectomy in the Treatment of Stage I and II Breast Cancer

1995 • 890 citations

Radiotherapy after Breast-Preserving Surgery in Women with Localized Cancer of the Breast

1993 • 756 citations

Randomized Clinical Trial of Breast Irradiation Following Lumpectomy and Axillary Dissection for Node-Negative Breast Cancer: an Update

1996 • 585 citations

Ten-year results of a randomized trial comparing a conservative treatment to mastectomy in early breast cancer

1989 • 567 citations

Significance of ipsilateral breast tumour recurrence after lumpectomy

1991 • 556 citations

Prognostic factors of breast recurrence in the conservative management of early breast cancer: A 25-year follow-up

1989 • 514 citations

Local Recurrences and Distant Metastases After Conservative Breast Cancer Treatments: Partly Independent Events

1995 • 511 citations

Breast conservation is the treatment of choice in small breast cancer: Long-term results of a randomized trial

1990 • 501 citations

Age as prognostic factor in premenopausal breast carcinoma

1993 • 482 citations

The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy

1994 • 482 citations

The Sequencing of Chemotherapy and Radiation Therapy after Conservative Surgery for Early-Stage Breast Cancer

1996 • 450 citations

Randomized clinical trial to assess the value of breast-conserving therapy in stage I and II breast cancer, EORTC 10801 trial.

1992 • 447 citations

Local recurrence after breast-conserving surgery and radiotherapy. Frequency, time course, and prognosis

1989 • 424 citations

Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial

1996 • 418 citations

The importance of the lumpectomy surgical margin status in long term results of breast conservation

1995 • 414 citations

Quadrantectomy versus lumpectomy for small size breast cancer

1990 • 413 citations

Infiltrating lobular carcinoma of the breast: Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns

1996 • 410 citations

A Randomized Clinical Trial Evaluating Sequential Methotrexate and Fluorouracil in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor-Negative Tumors

1989 • 400 citations

Pathologic findings from the national surgical adjuvant breast project (protocol 6). Relation of local breast recurrence to multicentricity

1986 • 387 citations

Younger women with breast carcinoma have a poorer prognosis than older women

1996 • 357 citations

Sector Resection With or Without Postoperative Radiotherapy for Stage I Breast Cancer: Five-Year Results of a Randomized Trial

1994 • 351 citations

Breast recurrence following conservative surgery and radiation: patterns of failure, prognosis, and pathologic findings from mastectomy specimens with implications for treatment

1990 • 343 citations

Pathologic margin involvement and the risk of recurrence in patients treated with breast‐conserving therapy

1996 • 306 citations

Pathologic margin involvement and the risk of recurrence in patients treated with breast-conserving therapy

1996 • 287 citations

Risk factors in breast-conservation therapy.

1994 • 273 citations

Dose Specification for Reporting External Beam Therapy with Photons and Electrons

1979 • 258 citations

Ten year results of conservative surgery and irradiation for stage I and II breast cancer

1991 • 249 citations

The influence of young age on outcome in early stage breast cancer

1994 • 247 citations

Infiltrating lobular carcinoma. Is it different from infiltrating duct carcinoma?

1994 • 220 citations

The significance of the pathology margins of the tumor excision on the outcome of patients treated with definitive irradiation for early stage breast cancer

1991 • 216 citations

Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: Results from a randomized trial

1994 • 214 citations

The Impact of tumor size and histology on local control after breast-conserving therapy

1988 • 214 citations

Risk factors for breast recurrence in premenopausal and postmenopausal patients with ductal cancers treated by conservation therapy

1990 • 203 citations

Long-term outcome following breast-conserving surgery and radiation therapy

1995 • 193 citations

Ten-year results in 1070 patients with stages I and II breast cancer treated by conservative surgery and radiation therapy

1995 • 191 citations

The Paris System in Interstitial Radiation Therapy

1978 • 188 citations

Radical radiation therapy of breast cancer

1980 • 185 citations

The effect of young age on tumor recurrence in the treated breast after conservative surgery and radiotherapy

1988 • 184 citations

The prognostic significance of late local recurrence after breast-conserving therapy

1990 • 182 citations

Breast-conserving Therapy for Macroscopically Multiple Cancers

1990 • 181 citations

Tumor excision and radiotherapy as primary treatment of breast cancer. Analysis of patient and treatment parameters and local control

1987 • 176 citations

Prognosis following local recurrence in the conservatively treated breast cancer patient

1991 • 173 citations

Factors influencing local recurrence after excision and radiotherapy for primary breast cancer

1989 • 155 citations

Prognostic factors for breast recurrence after conservative breast surgery and radiotherapy: results from a randomised trial

1996 • 153 citations

Results of conservative surgery and radiation therapy for multiple synchronous cancers of one breast

1989 • 137 citations

Margin Status and Local Recurrence After Breast-Conserving Surgery

1994 • 136 citations

Inaccuracies in using the lumpectomy scar for planning electron boosts in primary breast carcinoma

1994 • 130 citations

Tumor margin assessment as a guide to optimal conservation surgery and irradiation in early stage breast carcinoma

1989 • 125 citations

Prognostic factors for recurrence and cosmesis in 393 patients after radiation therapy for early mammary carcinoma.

1989 • 120 citations

Local relapse and contralateral tumor rates in patients with breast cancer treated with conservative surgery and radiotherapy (institut gustave roussy 1970–1982)

1995 • 106 citations

Breast conservation treatment of early stage breast cancer: patterns of failure

1995 • 106 citations

Prognostic implications of age in breast cancer patients treated with tumorectomy and irradiation or with mastectomy

1988 • 103 citations

Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting

1993 • 102 citations

Conservative treatment of early breast cancer

1988 • 101 citations

Timing of radiotherapy and chemotherapy following breast-conserving surgery for patients with node-positive breast cancer

1996 • 96 citations

Outcome of conservative therapy for invasive breast cancer by histologic subtype

1992 • 93 citations

Conservative surgery and radiation in the treatment of synchronous ipsilateral breast cancers

1993 • 91 citations

Infiltrating Lobular Carcinoma

1984 • 89 citations

Early breast cancer: influence of type of boost (electrons vs iridium-192 implant) on local control and cosmesis after conservative surgery and radiation therapy

1995 • 85 citations

Patterns of dose variability in radiation prescription of breast cancer

1997 • 83 citations

Conservative treatment of early breast cancer: Prognostic value of the ductal in situ component and other pathological variables on local control and survival

1989 • 81 citations

Histologic features predictive of an increased risk of early local recurrence after treatment of breast cancer by local tumor excision and radical radiotherapy.

1989 • 77 citations

Breast preservation in stage I and II carcinoma of the breast: The University of Chicago experience

1996 • 76 citations

Relation between time-dose and local control of operable breast cancer treated by tumorectomy and radiotherapy or by radical radiotherapy alone

1978 • 70 citations

Results of salvage mastectomy for local recurrence after breast-conserving surgery without radiation therapy

1993 • 68 citations

Recurrence in the breast following conservative surgery and radiation therapy for early-stage breast cancer.

1992 • 64 citations

Prognostic significance of breast relapse after conservative treatment in node-negative early breast cancer

1990 • 61 citations

Infiltrating breast carcinoma in patients age 30 years and younger: Long term outcome for life, relapse, and second primary tumors

1992 • 60 citations

Relationship of tumor grade to other pathologic features and to treatment outcome of patients with early stage breast carcinoma treated with breast-conserving therapy

1996 • 60 citations

Conservative surgery and radiation therapy for infiltrating lobular carcinoma of the breast: The role of preoperative mammograms in guiding treatment

1994 • 60 citations

Quality assurance of the EORTC trial 22881/10882: “assessment of the role of the booster dose in breast conserving therapy”: the Dummy Run

1991 • 59 citations

Should multicentric disease be an absolute contraindication to the use of breast-conserving therapy?

1994 • 54 citations

Local recurrence after breast-conserving surgery for breast cancer.

1996 • 48 citations

The impact of radiation on early breast carcinoma survival: A Bayesian analysis

1996 • 41 citations

Local recurrence after breast-conserving surgery for breast cancer

1996 • 40 citations

Breast conservation: long-term australian data

1992 • 36 citations

Prognostic value of DNA flow cytometry in the locally recurrent, conservatively treated breast cancer patient.

1992 • 24 citations

How important is adequate radiotherapy for the long-term results of breast-conserving treatment?

1991 • 22 citations

An Evaluation of the Antiproteolytic Reaction of Serum as a Test for Malignant Neoplasia<xref ref-type="fn" rid="fn1"><sup>2</sup></xref><xref ref-type="fn" rid="fn2"><sup>3</sup></xref>

1950 • 17 citations

Pathological features predictive of local recurrence after management by conservation of invasive breast cancer: importance of non-invasive carcinoma

1992 • 14 citations

Disappearance of the in situ component: a criterion predictive of metastasis in breast cancer after local relapse

1992 • 5 citations

The Academy stumbles, then advances, under fire

1996 • 3 citations

Deleted Work

1955 • 0 citations