Atipamezole increases medetomidine clearance in the dog: an agonist—antagonist interaction

Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist

1988 • 676 citations

Pharmacological profiles of medetomidine and its antagonist, atipamezole.

1989 • 290 citations

PCNONLIN and NONLIN84: Software for the Statistical Analysis of Nonlinear Models

1986 • 164 citations

EVIDENCE FOR MEDETOMIDINE AS A SELECTIVE AND POTENT AGONIST α₂‐ADRENORECEPTORS

1986 • 145 citations

Xylazine-induced depression and its antagonism by alpha adrenergic blocking agents.

1981 • 121 citations

Sedative and analgesic effects of medetomidine in dogs

1989 • 113 citations

Introduction to the clinical pharmacology of medetomidine.

1989 • 104 citations

Pharmacokinetics of medetomidine.

1989 • 100 citations

Medetomidine, a new sedative‐analgesic for use in the dog and its reversal with atipamezole

1989 • 97 citations

The clinical effectiveness of atipamezole as a medetomidine antagonist in the dog

1990 • 57 citations

HYPOTENSIVE AND SEDATIVE EFFECTS OF α‐ADRENOCEPTOR AGONISTS: RELATIONSHIP TO α₁‐AND α₂‐ADRENOCEPTOR POTENCY

1981 • 45 citations

Picogram level determination of medetomidine in dog serum by capillary gas chromatography with negative ion chemical ionization mass spectrometry

1989 • 42 citations

Medetomidine, a new sedative and analgesic drug for dogs and cats: A Summary

1986 • 39 citations

Sedative action of the α₂‐agonist medetomidine in cats

1987 • 35 citations

Clinical effectiveness of atipamezole as a medetomidine antagonist in cats

1990 • 32 citations

Biotransformation of medetomidine in the rat

1990 • 31 citations

Hemodynamic and anesthetic effects of etomidate infusion in medetomidine-premedicated dogs

1994 • 26 citations

Pharmacokinetics of xylazine in ponies: influence of yohimbine.

1987 • 16 citations