Stage-specific selection of alternative transcriptional initiation sites from the 5C actin gene of Drosophila melanogaster.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

1983 • 2,298 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

Repeated Genes in Eukaryotes

1980 • 1,383 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Multiple upstream AUG codons mediate translational control of GCN4

1986 • 654 citations

Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency

1985 • 645 citations

Intracellular localization of messenger RNAs for cytoskeletal proteins

1986 • 639 citations

c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

1984 • 601 citations

Three myosin heavy-chain isozymes appear sequentially in rat muscle development

1981 • 589 citations

The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.

1982 • 558 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation.

1979 • 501 citations

COMPLEX TRANSCRIPTIONAL UNITS: DIVERSITY IN GENE EXPRESSION BY ALTERNATIVE RNA PROCESSING

1986 • 486 citations

The actin genes of drosophila: a dispersed multigene family

1980 • 470 citations

Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver

1983 • 469 citations

Transcripts of the six Drosophila actin genes accumulate in a stage- and tissue-specific manner

1983 • 459 citations

Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22

1986 • 455 citations

Estrogen stabilizes vitellogenin mRNA against cytoplasmic degradation

1983 • 440 citations

The messenger RNA for alcohol dehydrogenase in Drosophila melanogaster differs in its 5′ end in different developmental stages

1983 • 415 citations

Alternative transcription and two modes of splicing result in two myosin light chains from one gene

1984 • 400 citations

[38] Nucleic acid hybridization in cytological preparations

1971 • 368 citations

Cell type-specific activation of actin genes in the early amphibian embryo

1984 • 354 citations

The actin genes of drosophila: Protein coding regions are highly conserved but intron positions are not

1981 • 322 citations

Intricate combinatorial patterns of exon splicing generate multiple regulated troponin T isoforms from a single gene

1985 • 314 citations

A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternate splicing.

1985 • 305 citations

Repeated Gene Families in Drosophila melanogaster

1978 • 297 citations

The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader

1985 • 291 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions

1980 • 286 citations

The SV40 early region TATA box is required for accurate in vitro initiation of transcription

1981 • 269 citations

Fast skeletal muscle myosin light chains 1 and 3 are produced from a single gene by a combined process of differential RNA transcription and splicing.

1984 • 265 citations

A single locus in the mouse encodes both myosin light chains 1 and 3, a second locus corresponds to a related pseudogene

1984 • 256 citations

Transcription termination at the trp operon attenuators of Escherichia coli and Salmonella typhimurium: RNA secondary structure and regulation of termination.

1977 • 232 citations

Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogaster.

1986 • 223 citations

The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segments

1986 • 187 citations

Cell lineage-specific programs of expression of multiple actin genes during sea urchin embryogenesis

1986 • 178 citations

Molecular and Cell Isoforms During Development

1983 • 172 citations

Highly conserved sequencim in the 3′ untranslated region of mRNAs coding for homologous proteins in distantly related species

1985 • 155 citations

Multiple actin-related sequences in the Drosophila melanogaster genome

1980 • 154 citations

An Improved strategy for rapid direct sequencing of both strands of long DNA molecules cloned in a plasmid

1983 • 153 citations

Heterogeneity at the 5' termini of mouse dihydrofolate reductase mRNAs. Evidence for multiple promoter regions.

1985 • 145 citations

Multigene families encoding actin and tubulin

1981 • 132 citations

Differential expression and 5′ end mapping of actin genes in Dictyostelium

1981 • 127 citations

Tissue-specific expression of two mRNA species transcribed from a single vimentin gene

1983 • 123 citations

Two Drosophila actin genes in detail gene structure, protein structure and transcription during development

1983 • 107 citations

Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5' untranslated region.

1985 • 104 citations

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

1983 • 103 citations

Evolution of the human sarcomeric-actin genes: Evidence for units of selection within the 3′ untranslated regions of the mRNAs

1984 • 100 citations

Multiple origins of transcription in the 4.5 Kb upstream of the ϵ-globin gene

1983 • 98 citations

The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species.

1986 • 97 citations

Regulatory elements involved in Drosophila Adh gene expression are conserved in divergent species and separate elements mediate expression in different tissues.

1986 • 89 citations

Structure and complete nucleotide sequence of the chicken alpha-smooth muscle (aortic) actin gene. An actin gene which produces multiple messenger RNAs.

1986 • 79 citations

Molecular structure of the human argininosuccinate synthetase gene: occurrence of alternative mRNA splicing.

1984 • 68 citations

The human albumin gene. Characterization of the 5‘ and 3‘ flanking regions and the polymorphic gene transcripts.

1986 • 66 citations

The untranslated regions of β-globin mRNA evolve at a functional rate in higher primates

1981 • 44 citations

Different rates of mRNA translation balance the expression of the two human alpha-globin loci.

1982 • 36 citations

Molecular cloning of the gene sequences of a major apoprotein in avian very low density lipoproteins

1980 • 34 citations

Roles of the 5′ leader region of the ompA mRNA

1984 • 34 citations

Three sea urchin actin genes show different patterns of expression: muscle specific, embryo specific, and constitutive.

1984 • 34 citations

Transcription attenuation in Salmonella typhimurium: the significance of rare leucine codons in the leu leader.

1986 • 32 citations

Actin gene expression is modulated by ecdysterone in a Drosophila cell line

1983 • 28 citations

The size of poly(A)-containing RNAs in Drosophila melanogaster embryos

1976 • 26 citations